Search Results - "Douillet, Delphine"
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Uncoupling histone H3K4 trimethylation from developmental gene expression via an equilibrium of COMPASS, Polycomb and DNA methylation
Published in Nature genetics (01-06-2020)“…The COMPASS protein family catalyzes histone H3 Lys 4 (H3K4) methylation and its members are essential for regulating gene expression. MLL2/COMPASS methylates…”
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Right iliac deep vein thrombosis and pulmonary embolism associated with recreational nitrous oxide: a case report
Published in International journal of emergency medicine (04-11-2024)“…Background The recreational use of nitrous oxide is becoming increasingly common among teenagers and young adults. Since 2018, the use of nitrous oxide has…”
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Metabolomics and proteomics identify the toxic form and the associated cellular binding targets of the anti-proliferative drug AICAR
Published in The Journal of biological chemistry (18-01-2019)“…5-Aminoimidazole-4-carboxamide 1-β-d-ribofuranoside (AICAR, or acadesine) is a precursor of the monophosphate derivative 5-amino-4-imidazole carboxamide…”
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Point-of-care ultrasonography for risk stratification of non-critical suspected COVID-19 patients on admission (POCUSCO): A prospective binational study
Published in PloS one (26-04-2023)“…Background Lung point-of-care ultrasonography (L-POCUS) is highly effective in detecting pulmonary peripheral patterns and may allow early identification of…”
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Use of troponin assay after electrical injuries: a 15-year multicentre retrospective cohort in emergency departments
Published in Scandinavian journal of trauma, resuscitation and emergency medicine (26-09-2021)“…Abstract Background Patients with electrical injury are considered to be at risk of cardiac arrhythmia. Assessing the risk of developing a major adverse…”
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Point-of-care ultrasonography for risk stratification of non-critical suspected COVID-19 patients on admission (POCUSCO): A prospective binational study
Published in PloS one (26-04-2023)“…Lung point-of-care ultrasonography (L-POCUS) is highly effective in detecting pulmonary peripheral patterns and may allow early identification of patients who…”
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Evaluating the impact of a standardised intervention for announcing decisions of withholding and withdrawing life-sustaining treatments on the stress of relatives in emergency departments (DISCUSS): protocol for a stepped-wedge randomised controlled trial
Published in BMJ open (05-09-2024)“…IntroductionThe decisions of withholding or withdrawing life-sustaining treatments are difficult to make in the context of emergency departments (EDs) because…”
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Efficacy and safety of antibiotics targeting Gram-negative bacteria in nosocomial pneumonia: a systematic review and Bayesian network meta-analysis
Published in Annals of intensive care (25-04-2024)“…Background Multiple randomized controlled studies have compared numerous antibiotic regimens, including new, recently commercialized antibiotics in the…”
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How to Combat Over-Testing for Patients Suspected of Pulmonary Embolism: A Narrative Review
Published in Diagnostics (Basel) (01-04-2023)“…The diagnosis of PE remains difficult in 2023 because the signs and symptoms are not sensible nor specific. The consequences of potential diagnostic errors can…”
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Pulmonary Embolism and Respiratory Deterioration in Chronic Cardiopulmonary Disease: A Narrative Review
Published in Diagnostics (Basel) (01-01-2023)“…Patients with chronic cardiopulmonary pathologies have an increased risk of developing venous thromboembolic events. The worsening of dyspnoea is a frequent…”
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Thromboembolic risk stratification by TRiP(cast) score to rationalise thromboprophylaxis in patients with lower leg trauma requiring immobilisation: a study protocol of the casting stepped-wedge cluster randomised trial
Published in BMJ open (28-06-2021)“…IntroductionPatients with lower limb trauma requiring orthopaedic immobilisation may be at risk of venous thromboembolism but opinions differ about who may…”
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Clinical risk assessment model to predict venous thromboembolism risk after immobilization for lower-limb trauma
Published in EClinicalMedicine (01-03-2020)“…Patients with lower-limb trauma requiring immobilization have an increased risk of venous thromboembolism (VTE). While thromboprophylaxis for all patients…”
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Validation of risk assessment models predicting venous thromboembolism in acutely ill medical inpatients: A cohort study
Published in Journal of thrombosis and haemostasis (01-06-2020)Get full text
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Comparison between conventional duplex ultrasonography and the dual-gate Doppler mode for hemodynamic measurements of the carotid arteries
Published in Medical ultrasonography (01-04-2022)“…This study investigated the correlations of hemodynamic parameters measured to quantify stenosis between the gold-standard duplex ultrasonography and the…”
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Oxygen therapy in acute hypoxemic respiratory failure: guidelines from the SRLF-SFMU consensus conference
Published in Annals of intensive care (05-09-2024)“…Introduction Although largely used, the place of oxygen therapy and its devices in patients with acute hypoxemic respiratory failure (ARF) deserves to be…”
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Impact of a strategy based on unique blood culture sampling on contamination rate and detection of bloodstream infections in critically ill patients
Published in Annals of intensive care (03-03-2023)“…Background Unique blood culture (UBC) has been proposed to limit the number of venipuncture and to decrease the risk of BC contaminations (BCC) without…”
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Point-of-care ultrasonography for risk stratification of non-critical COVID-19 patients on admission (POCUSCO): a study protocol of an international study
Published in BMJ open (10-02-2021)“…IntroductionIn the context of the COVID-19 pandemic, early identification of patients who are likely to get worse is a major concern. Severity mainly depends…”
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Coordinated regulation of cellular identity-associated H3K4me3 breadth by the COMPASS family
Published in Science advances (01-06-2020)“…Set1A and Set1B, two members of the COMPASS family of methyltransferases that methylate the histone H3 lysine 4 (H3K4) residue, have been accredited as primary…”
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Prevalence and characterization of forgoing care: comparison of two prospective multicentre cohorts between pre-COVID-19 era and a lockdown period
Published in Archives of public health = Archives belges de santé publique (19-01-2022)“…Little is known about patients who forego healthcare, although it is an important provider of unfavorable health-related outcomes. Forgoing healthcare…”
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