Search Results - "Douglass, Larry E."

Transcription factors WT1 and p53 combined: a prognostic biomarker in ovarian cancer by Carter, Julia H., Deddens, James A., Mueller, Gretchen, Lewis, Thomas G., Dooley, Mariah K., Robillard, Michelle C., Frydl, Molly, Duvall, Lydia, Pemberton, Jackson O., Douglass, Larry E.

“…Background New approaches to ovarian cancer are needed to improve survival. Wilms’ tumour 1 (WT1) is a tumour-associated antigen expressed in many ovarian…”
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Therapeutic suppression of translation initiation factor eIF4E expression reduces tumor growth without toxicity by Graff, Jeremy R, Konicek, Bruce W, Vincent, Thomas M, Lynch, Rebecca L, Monteith, David, Weir, Spring N, Schwier, Phil, Capen, Andrew, Goode, Robin L, Dowless, Michele S, Chen, Yuefeng, Zhang, Hong, Sissons, Sean, Cox, Karen, McNulty, Ann M, Parsons, Stephen H, Wang, Tao, Sams, Lillian, Geeganage, Sandaruwan, Douglass, Larry E, Neubauer, Blake Lee, Dean, Nicholas M, Blanchard, Kerry, Shou, Jianyong, Stancato, Louis F, Carter, Julia H, Marcusson, Eric G

“…Expression of eukaryotic translation initiation factor 4E (eIF4E) is commonly elevated in human and experimental cancers, promoting angiogenesis and tumor…”
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Pak-1 Expression Increases with Progression of Colorectal Carcinomas to Metastasis by CARTER, Julia H, DOUGLASS, Larry E, DEDDENS, James A, COLLIGAN, Bruce M, BHATT, Tejal R, PEMBERTON, Jackson O, KONICEK, Susan, HOM, Joanne, MARSHALL, Mark, GRAFF, Jeremy R

“…Purpose: The p21-activated kinase-1 (Pak-1) promotes cell motility and invasiveness. Pak-1 is activated by the Rac, Rho, and Cdc42 small GTPases in response to…”
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Int7G24A Variant of Transforming Growth Factor-β Receptor Type I Is Associated with Invasive Breast Cancer by TAIPING CHEN, JACKSON, Chad R, LINK, Andrew, MARKEY, Michael P, COLLIGAN, Bruce M, DOUGLASS, Larry E, PEMBERTON, Jackson O, DEDDENS, James A, GRAFF, Jeremy R, CARTER, Julia H

“…Purpose: The transforming growth factor-β (TGF-β) signaling pathway has been frequently implicated in breast cancer. An intronic variant ( Int7G24A ) of TGF-β…”
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Phosphorylation of eIF4E serine 209 is associated with tumour progression and reduced survival in malignant melanoma by Carter, Julia H, Deddens, James A, Spaulding IV, Nelson Reed, Lucas, Denise, Colligan, Bruce M, Lewis, Thomas Grant, Hawkins, Elyse, Jones, Jordan, Pemberton, Jackson O, Douglass, Larry E, Graff, Jeremy R

“…Background: Melanoma is a disease that primarily arises in the skin but is a derivative of the neural crest. Eukaryotic translation initiation factor 4E…”
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eIF4E Activation Is Commonly Elevated in Advanced Human Prostate Cancers and Significantly Related to Reduced Patient Survival by GRAFF, Jeremy R, KONICEK, Bruce W, HURST, Bernadette M, DEDDENS, James A, NEUBAUER, Blake L, STANCATO, Louis F, CARTER, Harry W, DOUGLASS, Larry E, CARTER, Julia H, LYNCH, Rebecca L, DUMSTORF, Chad A, DOWLESS, Michele S, MCNULTY, Ann M, PARSONS, Stephen H, BRAIL, Leslie H, COLLIGAN, Bruce M, KOOP, Jonathan W

“…Elevated eukaryotic translation initiation factor 4E (eIF4E) function induces malignancy in experimental models by selectively enhancing translation of key…”
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Abstract 2267: Alterations in TGFβ signaling in ovarian cancer patients with TGFβ receptor 1 variants by Carter, Julia H., Schaeper, James P., Chen, Taiping, Fritz, Diane W., Focke, Leah, Guy, Adrian, Deddens, James A., Douglass, Larry E.

“…Abstract Transforming growth factor β (TGFβ) signals through the TGFβ Receptor 1 (TGFβR1) and is implicated in many aspects of malignancy. TGFβR1 gene is…”
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Abstract 2653: Cell proliferation and Cathepsin L expression are inversely correlated in bladder cancer progression and patient survival by Douglass, Larry E., Robillard, Michelle C., Stelzer, Dan, Dooley, Mariah, Deddens, James A., Carter, Julia H.

“…Abstract In 2017 there will be an estimated 79,000 new cases of bladder cancer (UBC) resulting in 16,870 deaths. A better understanding of UBC progression and…”
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Abstract 747: Pak1, TGFα, Ki 67 and survival in human gastric and gastroesophageal junction adenocarcinomas by Douglass, Larry E., Parritt, Michael, Neltner, Adam, Dooley, Mariah, Robillard, Michelle, Frydl, Molly, Focke, Leah, Damen, Kyle, Deddens, James A., Carter, Julia H.

“…Abstract Stomach cancer is the third most common cause of cancer mortality worldwide. Most are adenocarcinomas. Adenocarcinomas of the stomach fall into two…”
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Abstract 2793: Evidence for WT1 as a potential target for immunotherapy of lethal ovarian cancer by Carter, Julia H., Deddens, James A., Mueller, Gretchen, Lewis, Thomas G., Dooley, Mariah K., Pemberton, Jackson O., Douglass, Larry E.

“…Abstract Epithelial ovarian cancer is the leading cause of death from gynecologic cancers with 22,280 new cases anticipated in 2016 and 14,240 deaths. Most…”
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Abstract 5130: Prognostic significance of loss of Cathepsin L expression in urinary bladder cancer progression by Carter, Julia H., Deddens, James A., Robillard, Michelle C., Dooley, Mariah K., Stelzer, Daniel, Taylor, Zachary S., Douglass, Larry E.

“…Abstract During 2021 there will be 83,730 new cases of urinary bladder cancer (UBC) in the US and 17,200 UBC deaths. Most UBC arise from the urothelial lining…”
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Vascular and tumor cell expression of VEGFR2 and molecular subtyping: An innovative biomarker approach in bladder cancer by Nasir, Aejaz, Falcon, Beverly L, Wang, Dan, Holzer, Timothy R., Nonte, Elizabeth M, Chen, Mia Yang, Fulford, Angie D, Carter, Julia H, Douglass, Larry E, Pytowski, Bronislaw, Bell-McGuinn, Katherine M, Walgren, Richard A., Schade, Andrew E, Chaudhry, Aafia

“…Abstract only 497 Background: Treatment approaches combining anti-angiogenic therapy with chemotherapy have shown promising clinical results in metastatic…”
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Abstract 3919: Phosphorylation of eIF4E is a critical factor in development and progression of breast cancer in women by Dumstorf, Chad A., Douglass, Larry E., Deddens, James A., Lewis, Thomas G., Darpel, Kyle, Gausvik, Christian, Graff, Jeremy R., Carter, Julia H.

“…Abstract Breast cancer survival rates vary according to stage, tumor grade, and receptor status. While some cancer patients respond well to targeted therapy…”
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Abstract A28: Eukaryotic initiation factor 4E phosphorylation in human malignant melanoma by Carter, Julia H., Spaulding, Reed, Deddens, James A., Colligan, Bruce M., Lewis, Grant, Pemberton, Jackson O., Graff, Jeremy R., Douglass, Larry E.

“…Abstract Malignant melanoma continues to be a challenge both in terms of understanding the biologic mechanisms behind its behavior, as well as applying that…”
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Abstract 22: Overexpression of PAK 1 is a favorable prognostic biomarker in malignant melanoma by Carter, Julia H., Spaulding, Nelson R., Colligan, Bruce M., Deddens, James A., Douglass, Larry E.

“…Abstract The incidence of malignant melanoma, the most lethal form of skin cancer, is increasing. Approximately 76,000 new cases of invasive melanoma and 9,000…”
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Abstract 4172: Overexpression of Cathepsin L is associated with prostate cancer development, progression, and reduced patient survival by Carter, Julia H., Douglass, Larry E., Deddens, James A., Colligan, Bruce M., Hurst, Bernadette M., Pullman, Janice, Richmond, Raymond E., Carter, Harry W.

“…Abstract Although an estimated 217,730 men will develop prostate cancer in 2010, only 15% (32,050) will die of this disease. To avoid overtreatment, new…”
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Abstract 1183: Association of germline variants of the TGFβR1 gene in colorectal cancer patients by Schaeper, James P., Murray, Kevin, DeBrosse, Jessica L., Vogt, Briana, Lucas, Denise, Colligan, Bruce M., Deddens, James A., Douglass, Larry E., Graff, Jeremy R., Carter, Julia H.

“…Abstract Colorectal cancer is the second leading cause of cancer death in the United States and approximately 147,000 new cases of colorectal cancer (CRC) were…”
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Acute varieties of melioidosis occurring in U. S. soldiers in Vietnam by Weber, D R, Douglass, L E, Brundage, W G, Stallkamp, T C

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