Search Results - "Douglas E. Smith"
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Effect of Process Parameters on Void Distribution, Volume Fraction, and Sphericity within the Bead Microstructure of Large-Area Additive Manufacturing Polymer Composites
Published in Polymers (24-11-2022)“…Short carbon fiber-reinforced composite materials produced by large-area additive manufacturing (LAAM) are attractive due to their lightweight, favorable…”
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Continuous Fiber Angle Topology Optimization for Polymer Composite Deposition Additive Manufacturing Applications
Published in Fibers (01-02-2019)“…Mechanical properties of parts produced with polymer deposition additive manufacturing (AM) depend on the print bead direction, particularly when short…”
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3
Nonequilibrium dynamics and ultraslow relaxation of confined DNA during viral packaging
Published in Proceedings of the National Academy of Sciences - PNAS (10-06-2014)“…Many viruses use molecular motors that generate large forces to package DNA to near-crystalline densities inside preformed viral proheads. Besides being a key…”
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Correlation of Microstructural Features within Short Carbon Fiber/ABS Manufactured via Large-Area Additive- Manufacturing Beads
Published in Journal of composites science (01-07-2024)“…Short carbon fiber-reinforced polymer composites are widely used in polymer extrusion additive manufacturing (AM), including large-area additive manufacturing…”
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Rheology Effects on Predicted Fiber Orientation and Elastic Properties in Large Scale Polymer Composite Additive Manufacturing
Published in Journal of composites science (01-03-2018)“…Short fiber-reinforced polymers have recently been introduced to large-scale additive manufacturing to improve the mechanical performances of printed-parts. As…”
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Onset of Non-Continuum Effects in Microrheology of Entangled Polymer Solutions
Published in Macromolecules (11-02-2014)“…Microrheology has emerged as a powerful approach for elucidating mechanical properties of soft materials and complex fluids, especially biomaterials. In this…”
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Diffusion of Isolated DNA Molecules: Dependence on Length and Topology
Published in Proceedings of the National Academy of Sciences - PNAS (09-05-2006)“…The conformation and dynamics of circular polymers is a subject of considerable theoretical and experimental interest. DNA is an important example because it…”
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Nucleotide-dependent DNA gripping and an end-clamp mechanism regulate the bacteriophage T4 viral packaging motor
Published in Nature communications (21-12-2018)“…ATP-powered viral packaging motors are among the most powerful biomotors known. Motor subunits arranged in a ring repeatedly grip and translocate the DNA to…”
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Continuous Allosteric Regulation of a Viral Packaging Motor by a Sensor that Detects the Density and Conformation of Packaged DNA
Published in Biophysical journal (20-01-2015)“…We report evidence for an unconventional type of allosteric regulation of a biomotor. We show that the genome-packaging motor of phage ϕ29 is regulated by a…”
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10
Biophysics of knotting
Published in Annual review of biophysics (01-01-2010)“…Knots appear in a wide variety of biophysical systems, ranging from biopolymers, such as DNA and proteins, to macroscopic objects, such as umbilical cords and…”
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11
Spontaneous knotting of an agitated string
Published in Proceedings of the National Academy of Sciences - PNAS (16-10-2007)“…It is well known that a jostled string tends to become knotted; yet the factors governing the "spontaneous" formation of various knots are unclear. We…”
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12
Strong effects of molecular topology on diffusion of entangled DNA molecules
Published in Proceedings of the National Academy of Sciences - PNAS (20-03-2007)“…When long polymers such as DNA are in a highly concentrated state they may become entangled, leading to restricted self-diffusion. Here, we investigate the…”
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13
Identification of a Rapidly Formed Nonnucleosomal Histone-DNA Intermediate that Is Converted into Chromatin by ACF
Published in Molecular cell (19-08-2011)“…Chromatin assembly involves the combined action of histone chaperones and ATP-dependent motor proteins. Here, we investigate the mechanism of nucleosome…”
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14
Single phage T4 DNA packaging motors exhibit large force generation, high velocity, and dynamic variability
Published in Proceedings of the National Academy of Sciences - PNAS (23-10-2007)“…Terminase enzyme complexes, which facilitate ATP-driven DNA packaging in phages and in many eukaryotic viruses, constitute a wide and potentially diverse…”
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15
The bacteriophage Φ29 portal motor can package DNA against a large internal force
Published in Nature (London) (01-10-2001)Get full text
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16
Prediction of the Fiber Orientation State and the Resulting Structural and Thermal Properties of Fiber Reinforced Additive Manufactured Composites Fabricated Using the Big Area Additive Manufacturing Process
Published in Journal of composites science (01-06-2018)“…Recent advances in Fused Filament Fabrication (FFF) include large material deposition rates and the addition of chopped carbon fibers to the filament…”
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17
Ionic effects on viral DNA packaging and portal motor function in bacteriophage φ29
Published in Proceedings of the National Academy of Sciences - PNAS (03-07-2007)“…In many viruses, DNA is confined at such high density that its bending rigidity and electrostatic self-repulsion present a strong energy barrier in viral…”
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Self-Diffusion of Entangled Linear and Circular DNA Molecules: Dependence on Length and Concentration
Published in Macromolecules (01-05-2007)“…Self-diffusion coefficients (D) of DNA molecules of varying length and concentration were measured by tracking the Brownian motion of individual fluorescently…”
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19
Direct measurement of the intermolecular forces confining a single molecule in an entangled polymer solution
Published in Physical review letters (21-09-2007)“…We use optical tweezers to directly measure the intermolecular forces acting on a single polymer imposed by surrounding entangled polymers (115 kbp DNA, 1…”
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20
Evidence for an electrostatic mechanism of force generation by the bacteriophage T4 DNA packaging motor
Published in Nature communications (17-06-2014)“…How viral packaging motors generate enormous forces to translocate DNA into viral capsids remains unknown. Recent structural studies of the bacteriophage T4…”
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