Search Results - "Douglas, Timothy E L"
-
1
Endothelialization of Whey Protein Isolate-Based Scaffolds for Tissue Regeneration
Published in Molecules (Basel, Switzerland) (01-10-2023)“…Background: Whey protein isolate (WPI) is a by-product from the dairy industry, whose main component is β-lactoglobulin. Upon heating, WPI forms a hydrogel…”
Get full text
Journal Article -
2
Whey Protein Isolate/Calcium Silicate Hydrogels for Bone Tissue Engineering Applications—Preliminary In Vitro Evaluation
Published in Materials (29-09-2023)“…Whey protein isolate (WPI) hydrogels are attractive biomaterials for application in bone repair and regeneration. However, their main limitation is low…”
Get full text
Journal Article -
3
The Effect of Chitosan on Physicochemical Properties of Whey Protein Isolate Scaffolds for Tissue Engineering Applications
Published in Polymers (23-09-2023)“…New scaffolds, based on whey protein isolate (WPI) and chitosan (CS), have been proposed and investigated as possible materials for use in osteochondral tissue…”
Get full text
Journal Article -
4
Generation of Pearl/Calcium Phosphate Composite Particles and Their Integration into Porous Chitosan Scaffolds for Bone Regeneration
Published in Journal of functional biomaterials (21-02-2024)“…Bone tissue engineering using osteoconductive scaffolds holds promise for regeneration, with pearl powder gaining interest for its bioactive qualities. This…”
Get full text
Journal Article -
5
Could Curdlan/Whey Protein Isolate/Hydroxyapatite Biomaterials Be Considered as Promising Bone Scaffolds?-Fabrication, Characterization, and Evaluation of Cytocompatibility towards Osteoblast Cells In Vitro
Published in Cells (Basel, Switzerland) (01-10-2022)“…The number of bone fractures and cracks requiring surgical interventions increases every year; hence, there is a huge need to develop new potential bone…”
Get full text
Journal Article -
6
Enzymatic Mineralization of Hydrogels for Bone Tissue Engineering by Incorporation of Alkaline Phosphatase
Published in Macromolecular bioscience (01-08-2012)“…Alkaline phosphatase (ALP), an enzyme involved in mineralization of bone, is incorporated into three hydrogel biomaterials to induce their mineralization with…”
Get full text
Journal Article -
7
The Enrichment of Whey Protein Isolate Hydrogels with Poly-γ-Glutamic Acid Promotes the Proliferation and Osteogenic Differentiation of Preosteoblasts
Published in Gels (01-01-2024)“…Osseous disease accounts for over half of chronic pathologies, but there is a limited supply of autografts, the gold standard; hence, there is a demand for new…”
Get full text
Journal Article -
8
WPI Hydrogels with a Prolonged Drug-Release Profile for Antimicrobial Therapy
Published in Pharmaceutics (04-06-2022)“…Infectious sequelae caused by surgery are a significant problem in modern medicine due to their reduction of therapeutic effectiveness and the patients’…”
Get full text
Journal Article -
9
Polylactide nanofibers with hydroxyapatite as growth substrates for osteoblast-like cells
Published in Journal of biomedical materials research. Part A (01-11-2014)“…Various types of nanofibers are increasingly used in tissue engineering, mainly for their ability to mimic the architecture of tissue at the nanoscale. We…”
Get full text
Journal Article -
10
Hierarchy of Hybrid Materials-The Place of Inorganics- in -Organics in it, Their Composition and Applications
Published in Frontiers in chemistry (04-04-2019)“…Hybrid materials, or hybrids incorporating both organic and inorganic constituents, are emerging as a very potent and promising class of materials due to the…”
Get full text
Journal Article -
11
Whey Protein Isolate as a Substrate to Design Calendula officinalis Flower Extract Controlled-Release Materials
Published in International journal of molecular sciences (13-05-2024)“…The use of natural active substances and the development of new formulations are promising directions in the cosmetic and pharmacy industries. The primary…”
Get full text
Journal Article -
12
Enzymatically induced mineralization of platelet-rich fibrin
Published in Journal of biomedical materials research. Part A (01-05-2012)“…Membranes of the autologous blood‐derived biomaterial platelet‐rich fibrin (PRF) were functionalized by incorporation of alkaline phosphatase (ALP), an enzyme…”
Get full text
Journal Article -
13
Dairy-Inspired Coatings for Bone Implants from Whey Protein Isolate-Derived Self-Assembled Fibrils
Published in International journal of molecular sciences (03-08-2020)“…To improve the integration of a biomaterial with surrounding tissue, its surface properties may be modified by adsorption of biomacromolecules, e.g., fibrils…”
Get full text
Journal Article -
14
Composites Based on Hydroxyapatite and Whey Protein Isolate for Applications in Bone Regeneration
Published in Materials (29-04-2021)“…Hydroxyapatite (HAp) is a bioactive ceramic with great potential for the regeneration of the skeletal system. However, its mechanical properties, especially…”
Get full text
Journal Article -
15
Heparin Enriched-WPI Coating on Ti6Al4V Increases Hydrophilicity and Improves Proliferation and Differentiation of Human Bone Marrow Stromal Cells
Published in International journal of molecular sciences (01-01-2022)“…Titanium alloy (Ti6Al4V) is one of the most prominent biomaterials for bone contact because of its ability to bear mechanical loading and resist corrosion. The…”
Get full text
Journal Article -
16
Effect of low-temperature plasma treatment of electrospun polycaprolactone fibrous scaffolds on calcium carbonate mineralisation
Published in RSC advances (22-11-2018)“…This article reports on a study of the mineralisation behaviour of CaCO 3 deposited on electrospun poly(-caprolactone) (PCL) scaffolds preliminarily treated…”
Get full text
Journal Article -
17
pH-Sensitive Dairy-Derived Hydrogels with a Prolonged Drug Release Profile for Cancer Treatment
Published in Materials (05-02-2021)“…A novel versatile biocompatible hydrogel of whey protein isolate (WPI) and two types of tannic acid (TAs) was prepared by crosslinking of WPI with TAs in a…”
Get full text
Journal Article -
18
Morphological, Mechanical and Mucoadhesive Properties of Electrospun Chitosan/Phospholipid Hybrid Nanofibers
Published in International journal of molecular sciences (02-08-2018)“…This study aimed to develop hybrid electrospun chitosan⁻phospholipid nanofibers and investigate the effect of phospholipid (P) content and chitosans (Ch)…”
Get full text
Journal Article -
19
Vaterite coatings on electrospun polymeric fibers for biomedical applications
Published in Journal of biomedical materials research. Part A (01-01-2017)“…The process of porous calcium carbonate (CaCO3) covering on electrospun poly(ε‐caprolactone) (PCL) fibers is described in this study. Uniform CaCO3 coatings,…”
Get full text
Journal Article -
20
Freeze-Dried Curdlan/Whey Protein Isolate-Based Biomaterial as Promising Scaffold for Matrix-Associated Autologous Chondrocyte Transplantation-A Pilot In-Vitro Study
Published in Cells (Basel, Switzerland) (14-01-2022)“…The purpose of this pilot study was to establish whether a novel freeze-dried curdlan/whey protein isolate-based biomaterial may be taken into consideration as…”
Get full text
Journal Article