Search Results - "Douglas, Lisa"

House dust mite allergens induce Ca2+ signalling and alarmin responses in asthma airway epithelial cells by Ouyang, Xuan, Reihill, James A., Douglas, Lisa E.J., Dunne, Orla M., Sergeant, Gerard P., Martin, S. Lorraine

“…Type 2 inflammation in asthma develops with exposure to stimuli to include inhaled allergens from house dust mites (HDM). Features include mucus hypersecretion…”
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Airborne indoor allergen serine proteases and their contribution to sensitisation and activation of innate immunity in allergic airway disease by Ouyang, Xuan, Reihill, James A, Douglas, Lisa E J, Martin, S Lorraine

“…Common airborne allergens (pollen, animal dander and those from fungi and insects) are the main triggers of type I allergic disorder in the respiratory system…”
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Furin as a therapeutic target in cystic fibrosis airways disease by Douglas, Lisa E J, Reihill, James A, Montgomery, Bethany M, Martin, S Lorraine

“…Clinical management of cystic fibrosis (CF) has been greatly improved by the development of small molecule modulators of the CF transmembrane conductance…”
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Modulation of Ion Transport to Restore Airway Hydration in Cystic Fibrosis by Reihill, James A, Douglas, Lisa E J, Martin, S Lorraine

“…Cystic fibrosis (CF) is a life-limiting genetic disorder caused by loss-of-function mutations in the gene which codes for the CF transmembrane conductance…”
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Mechanistic Dichotomy in Bacterial Trichloroethene Dechlorination Revealed by Carbon and Chlorine Isotope Effects by Lihl, Christina, Douglas, Lisa M, Franke, Steffi, Pérez-de-Mora, Alfredo, Meyer, Armin H, Daubmeier, Martina, Edwards, Elizabeth A, Nijenhuis, Ivonne, Sherwood Lollar, Barbara, Elsner, Martin

“…Tetrachloroethene (PCE) and trichloroethene (TCE) are significant groundwater contaminants. Microbial reductive dehalogenation at contaminated sites can…”
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An audit of the use of CT pituitary scans to exclude a pituitary macroadenoma by Douglas, Lisa, Caldwell, James, Bolland, Mark

“…Pituitary imaging is often required to exclude an adenoma suspected clinically or biochemically. Although magnetic resonance (MR) is the gold standard,…”
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A Novel Serine Protease Inhibitor PE-BBI Ameliorates Cockroach Extract-Mediated Airway Epithelial Barrier Dysfunction by Reihill, James A, Ouyang, Xuan, Yang, Zhixuan, Douglas, Lisa E J, Zhou, Mei, Chen, Tianbao, Martin, S Lorraine

“…Epithelial barrier dysfunction, characteristic of allergic airway disease may be, at least in part, due to the action of allergen-associated protease…”
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Comparison of Cervical Range-of-Motion Restriction and Craniofacial Tissue-Interface Pressure With 2 Adjustable and 2 Standard Cervical Collars by Tescher, Ann N, Rindflesch, Aaron B, Youdas, James W, Terman, Ross W, Jacobson, Therese M, Douglas, Lisa L, Miers, Anne G, Austin, Christine M, Delgado, Adriana M, Zins, Savannah M, Lahr, Brian D, Pichelmann, Mark A, Heller, Stephanie F, Huddleston, Paul M

“…STUDY DESIGN.Randomized controlled trial. OBJECTIVE.The aim of the study was to compare and contrast the restrictiveness and tissue-interface pressure (TIP)…”
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Association Between Elevated Whole Blood Epstein–Barr Virus (EBV)-encoded RNA EBV Polymerase Chain Reaction and Reduced Incidence of Acute Lung Allograft Rejection by Ahya, Vivek N., MD, Douglas, Lisa P., BSN, RN, Andreadis, Charalambos, MD, Arnoldi, Sharon, PhD, Svoboda, Jakub, MD, Kotloff, Robert M., MD, Hadjiliadis, Denis, MD, Sager, Jeffery S., MD, Woo, Y. Joseph, MD, Pochettino, Alberto, MD, Schuster, Stephen J., MD, Stadtmauer, Edward A., MD, Tsai, Donald E., MD, PhD

“…Background Accurate functional assessment of patient immunosuppression after solid-organ transplantation remains elusive. Despite therapeutic serum…”
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Enhancing Spatial Knowledge With Discrete Euclidean Virtual 3D Display Interfaces: Design Options by Saffell, Tiffany N., Colle, Herbert A., Bock, Ian M., Douglas, Lisa J.

“…Getting lost within Internet applications has been addressed with limited success by treating hypertext navigation as analogous to spatial navigation. One…”
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Comparing Magnetic Resonance Imaging and Contrast‐Enhanced Ultrasound (CEUS) for the Characterization of Nodules Found on Hepatocellular Carcinoma Surveillance by Burak, Kelly W., Douglas, Lisa, Congly, Stephen E.

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The Role of Patient Engagement in Surgical Site Infection Reduction: A Process Improvement Project by Cox, Jill, Douglas, Lisa, Wemmer, Valerie, Kaminsky, Kathleen

“…BACKGROUNDSurgical site infections (SSIs) are the second most common healthcare-associated infection, with prevention being a high-priority goal for all…”
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Patient Experience of Physical Restraint in the Acute Setting: A Systematic Review of the Qualitative Research Evidence by Douglas, Lisa, Donohue, Gráinne, Morrissey, Jean

“…The use of physical restraint is a contentious practice in the acute mental health setting. There are a plethora of guidelines surrounding the safe use of…”
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Comparing Magnetic Resonance Imaging and Contrast-Enhanced Ultrasound (CEUS) for the Characterization of Nodules Found on Hepatocellular Carcinoma Surveillance: CEUS is Our Clear Choice by Burak, Kelly W, Douglas, Lisa, Congly, Stephen E

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BOS-318 treatment enhances elexacaftor-tezacaftor-ivacaftor (ETI)-mediated improvements in airways hydration and mucociliary transport by Douglas, Lisa E.J., Reihill, James A., Martin, S. Lorraine

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Reducing Stress in Healthcare: Evidence from Using an Integration Design Model by Keefer, Robert, Douglas, Lisa

“…The rapid and broad adoption of electronic health record (EHR) systems has produced a technological burden that includes systems that have poor usability,…”
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Furin Inhibition as a Mechanism to Reduce Aberrant ENaC‐Mediated Sodium Transport and Rehydrate the Airways in Cystic Fibrosis Lung Disease by Douglas, Lisa E.J., Reihill, James A., Ho, Melisa W.‐Y., Axten, Jeffrey M., Martin, S. Lorraine

“…The epithelial sodium channel (ENaC) is found in a number of tissues including lung epithelia and is activated through proteolytic cleavage of its α and γ…”
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The effect of triple CFTR modulator therapy and azithromycin on ion channels and inflammation in cystic fibrosis by Melhim, Suhad Bani, Douglas, Lisa E.J., Reihill, James A., Downey, Damian G., Martin, S. Lorraine

“…Inflammation in cystic fibrosis (CF) airways is difficult to treat with well-established regimens often including azithromycin (AZ) as an immunomodulatory…”
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Characterization of Clozapine-Responsive Human T Cells by Ogese, Monday O, Lister, Adam, Jenkins, Rosalind E, Meng, Xiaoli, Alfirevic, Ana, Douglas, Lisa, Mcloughlin, Rachel, Silva, Edward, Park, B Kevin, Pirmohamed, Munir, Naisbitt, Dean J

“…Use of the atypical antipsychotic clozapine is associated with life-threatening agranulocytosis. The delayed onset and the association with HLA variants are…”
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Channel Activating Proteases : Molecular Targets for Correction of Sodium Channel Dysfunction in Cystic Fibrosis Airways Disease by Douglas, Lisa

“…Cystic fibrosis (CF) is an autosomal recessive disease, caused by mutations in the gene which codes for the CF transmembrane conductance regulator (CFTR)…”
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