Search Results - "Douglas, L L"

Diversity of molecular targets and signaling pathways for CBD by Almeida, Douglas L., Devi, Lakshmi A.

“…Cannabidiol (CBD) is the second most abundant component of the Cannabis plant and is known to have effects distinct from Δ9‐tetrahydrocannabinol (THC). Many…”
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Innate Immunity and the Failing Heart: The Cytokine Hypothesis Revisited by Mann, Douglas L.

“…Elevated levels of inflammatory mediators have been identified in patients with heart failure, including heart failure with reduced and preserved ejection…”
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Neurohormonal activation in heart failure with reduced ejection fraction by Hartupee, Justin, Mann, Douglas L.

“…Key Points Heart failure with reduced ejection fraction (HFrEF) is initiated when an 'index event' causes the pumping capacity of the heart to be impaired…”
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The Emerging Role of Innate Immunity in the Heart and Vascular System: For Whom the Cell Tolls by Mann, Douglas L

“…Recent studies suggest that the heart possesses an innate immune system that is intended to delimit tissue injury, as well as orchestrate homoeostatic…”
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A Practitioner's Guide to Cluster-Robust Inference by Cameron, A. Colin, Miller, Douglas L.

“…We consider statistical inference for regression when data are grouped into clusters, with regression model errors independent across clusters but correlated…”
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Exploring uncertainty measures in deep networks for Multiple sclerosis lesion detection and segmentation by Nair, Tanya, Precup, Doina, Arnold, Douglas L., Arbel, Tal

“…•Uncertainty enables deep learning frameworks to be adopted into clinical workflows.•Uncertainty reflects challenge of small lesion detection, lesion contour…”
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Reappraising the role of inflammation in heart failure by Adamo, Luigi, Rocha-Resende, Cibele, Prabhu, Sumanth D., Mann, Douglas L.

“…The observation that heart failure with reduced ejection fraction is associated with elevated circulating levels of pro-inflammatory cytokines opened a new…”
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The Emerging Field of Cardioimmunology: Past, Present and Foreseeable Future by Mann, Douglas L

“…Over the past 30 years, the field of cardioimmunology has moved from being dismissed as a field that was chasing an epiphenomenon of little biological…”
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Role of innate and adaptive immune mechanisms in cardiac injury and repair by Epelman, Slava, Liu, Peter P., Mann, Douglas L.

“…Key Points Cardiac injury can lead to cardiomyocyte death, intense inflammation, scar formation and, over time, adverse cardiac remodelling. Following injury,…”
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Designing the Next Generation of Chemical Separation Membranes by Gin, Douglas L., Noble, Richard D.

“…New materials can be prepared as membranes that may allow their performance to beat long-standing limits. Synthetic membranes are used in many separation…”
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Does paraquat cause Parkinson’s disease? A review of reviews by Weed, Douglas L.

“…•A review of reviews on paraquat and Parkinson’s disease was performed.•The available evidence does not support a causal conclusion.•Future research should…”
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Artificial Intelligence Discusses the Role of Artificial Intelligence in Translational Medicine: A JACC: Basic to Translational Science Interview With ChatGPT by Mann, Douglas L

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Endocrine Surgery at the NIH: History and Contributions by Fraker, Douglas L.

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Transcript Dynamics of Proinflammatory Genes Revealed by Sequence Analysis of Subcellular RNA Fractions by Bhatt, Dev M., Pandya-Jones, Amy, Tong, Ann-Jay, Barozzi, Iros, Lissner, Michelle M., Natoli, Gioacchino, Black, Douglas L., Smale, Stephen T.

“…Macrophages respond to inflammatory stimuli by modulating the expression of hundreds of genes in a defined temporal cascade, with diverse transcriptional and…”
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An Introductory Guide to Event Study Models by Miller, Douglas L.

“…The event study model is a powerful econometric tool used for the purpose of estimating dynamic treatment effects. One of its most appealing features is that…”
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A formal test of the theory of universal common ancestry by Theobald, Douglas L

“…Universal common ancestry (UCA) is a central pillar of modern evolutionary theory. As first suggested by Darwin, the theory of UCA posits that all extant…”
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Reviewing Residency Applications during the Pandemic by Hester, Douglas L.

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Causes, consequences, and cures for neuroinflammation mediated via the locus coeruleus: noradrenergic signaling system by Feinstein, Douglas L., Kalinin, Sergey, Braun, David

“…Aside from its roles in as a classical neurotransmitter involved in regulation of behavior, noradrenaline (NA) has other functions in the CNS. This includes…”
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Contribution of Relapse-Independent Progression vs Relapse-Associated Worsening to Overall Confirmed Disability Accumulation in Typical Relapsing Multiple Sclerosis in a Pooled Analysis of 2 Randomized Clinical Trials by Kappos, Ludwig, Wolinsky, Jerry S, Giovannoni, Gavin, Arnold, Douglas L, Wang, Qing, Bernasconi, Corrado, Model, Fabian, Koendgen, Harold, Manfrini, Marianna, Belachew, Shibeshih, Hauser, Stephen L

“…Accumulation of disability in multiple sclerosis may occur as relapse-associated worsening (RAW) or steady progression independent of relapse activity (PIRA),…”
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Elena Galea (1962–2023) by Feinstein, Douglas L.

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