Search Results - "Douglas, Alan W"

A practical process for the preparation of tetrahydro-1-methyl-3,3-diphenyl-1H,3H-pyrrolo[1,2-c][1,3,2]oxazaborole-borane. A highly enantioselective stoichiometric and catalytic reducing agent by Mathre, David J, Thompson, Andrew S, Douglas, Alan W, Hoogsteen, Karst, Carroll, James D, Corley, Edward G, Grabowski, Edward J. J

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Intramolecular Aromatic 1,5-Hydrogen Transfer in Free Radical Reactions 1. Unprecedented Rearrangements in Pschorr Cyclization, Sandmeyer, and Hydro-, Hydroxy-, and Iododediazoniation Reactions by Karady, Sandor, Abramson, N. Lee, Dolling, Ulf-H, Douglas, Alan W, McManemin, Gregory J, Marcune, Benjamin

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The behavior of indene oxide in the ritter reaction: A simple route to cis-aminoindanol by Senanayake, Chris H., Roberts, F.Edward, DiMichele, Lisa M., Ryan, Kenneth M., Liu, Ji, Fredenburgh, Laura E., Foster, Bruce S., Douglas, Alan W., Larsen, Robert D., Verhoeven, Thomas R., Reider, Paul J.

“…A regio- and stereoselective synthesis of cis-1-aminoindan-2-ol via a Ritter reaction is described. A regio- and stereoselective synthesis of chiral…”
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Practical Synthesis of Anti-Methicillin-Resistant Staphylococcus Aureus (MRSA) Carbapenem L-742,728 by Yasuda, Nobuyoshi, Huffman, Mark A, Ho, Guo-Jie, Xavier, Lyndon C, Yang, Chunhua, Emerson, Khateeta M, Tsay, Fuh-Rong, Li, Yulan, Kress, Michael H, Rieger, Dale L, Karady, Sandor, Sohar, Paul, Abramson, Newton L, DeCamp, Ann E, Mathre, David J, Douglas, Alan W, Dolling, Ulf-H, Grabowski, Edward J. J, Reider, Paul J

“…Anti-MRSA carbapenem, L-742,728, has been prepared in large quantity using the Suzuki−Miyaura cross-coupling as the key reaction. Three approaches have been…”
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Spirodioxolane intermediates in the reaction of 2-(trimethylsilyl)thiazole with aldehydes. Support for the 2-ylide mechanism by Dondoni, Alessandro, Douglas, Alan W, Shinkai, Ichiro

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A Highly Efficient Synthesis of Fibrinogen Receptor Antagonist L-734,217 via a Novel Chemoselective Silyl-Mediated Conjugate Addition of δ-Lactams to 4-Vinylpyridine by Chung, John Y. L, Hughes, David L, Zhao, Dalian, Song, Zhiguo, Mathre, David J, Ho, Guo-Jie, McNamara, James M, Douglas, Alan W, Reamer, R. A, Tsay, Fuh-Rong, Varsolona, Richard, McCauley, James, Grabowski, Edward J. J, Reider, Paul J

“…A highly practical chromatography-free six-step synthesis of L-734,217 suitable for large scale preparation is described. The key chiral pyridine acid…”
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Silylation-mediated oxidation of 4-aza-3-ketosteroids with DDQ proceeds via DDQ-substrate adducts by Bhattacharya, Apurba, DiMichele, Lisa M, Dolling, Ulf H, Douglas, Alan W, Grabowski, Edward J. J

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Stability and kinetics of degradation of imipenem in aqueous solution by Smith, G B, Dezeny, G C, Douglas, A W

“…In weakly acidic solution, the broad-spectrum antibiotic imipenem undergoes complex oligomerization initiated by intermolecular carboxyl group attack on the…”
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Iodotrimethylsilane-mediated 2-monohalogenation of 4-aza-5.alpha.-androstan-3-one steroids by King, Anthony O, Anderson, R. Kevin, Shuman, Richard F, Karady, Sandor, Abramson, N. Lee, Douglas, Alan W

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Biosynthesis of fluorothreonine and fluoroacetic acid by the thienamycin producer, Streptomyces cattleya by Sanada, M, Miyano, T, Iwadare, S, Williamson, J M, Arison, B H, Smith, J L, Douglas, A W, Liesch, J M, Inamine, E

“…An antimetabolite, THX, was isolated from fermentation broths of the thienamycin producer, Streptomyces cattleya, when the organism was grown in the presence…”
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Kinetics of a heterogeneous enzymic hydrolysis of a prochiral diester by Smith, George B, Bhupathy, Mahadevan, Dezeny, George C, Douglas, Alan W, Lander, Russel J

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Studies on the structures of imipenem, dehydropeptidase I-hydrolyzed imipenem, and related analogs by Ratcliffe, Ronald W, Wildonger, Kenneth J, Di Michele, Lisa, Douglas, Alan W, Hajdu, Richard, Goegelman, Robert T, Springer, James P, Hirshfield, Jordan

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In situ studies of chemical reactions by carbon-13 Fourier transform nuclear magnetic resonance. Application to the Fischer indole synthesis by Douglas, Alan W

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An unusual Fischer indole synthesis with 4-keto acids: an indole incorporating the terminal hydrazine nitrogen by Conn, Robin S. Eichen, Douglas, Alan W, Karady, Sandor, Corley, Edward G, Lovell, Alfred V, Shinkai, Ichiro

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Biosynthetic origin of the carbon skeleton and oxygen atoms of the avermectins by Cane, David E, Liang, Tzyy Chyau, Kaplan, Louis, Nallin, Mary K, Schulman, Marvin D, Hensens, Otto D, Douglas, Alan W, Albers-Schoenberg, Georg

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The structure of heneicomycin by Dewey, R S, Hensens, O D, Douglas, A W, Albers-Schönberg, G

“…The antibiotic heneicomycin (1), C44H62N2O11, was isolated from cultures of Streptomyces filipinensis as an amorphous yellow powder. Mass spectral and NMR…”
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Friedel-Crafts chemistry. A mechanistic study of the reaction of 3-chloro-4'-fluoro-2-methylpropiophenone with aluminum chloride and aluminum chloride-nitromethane by Pines, Seemon H, Douglas, Alan W

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Carbon-13 nuclear magnetic resonance spectroscopy of evolving reactions. Indanones via aluminum chloride- and sulfuric acid-catalyzed cyclialkylations by Pines, Seemon H, Douglas, Alan W

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The so-called hydroxymethylation reaction. Synthesis of 3-methoxy-2-methylpropiophenone by Pines, Seemon H, Douglas, Alan W

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Specific dealkylation of 3-benzyladenines in the presence of 9-benzyladenines by Weinstock, Leonard M, Tull, Roger J, Douglas, Alan W, Shinkai, Ichiro

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