Search Results - "Doughty, Emma L"

Longitudinal genomics reveals carbapenem-resistant Acinetobacter baumannii population changes with emergence of highly resistant ST164 clone by Liu, Haiyang, Moran, Robert A., Doughty, Emma L., Hua, Xiaoting, Snaith, Ann E., Zhang, Linghong, Chen, Xiangping, Guo, Feng, van Schaik, Willem, McNally, Alan, Yu, Yunsong

“…Carbapenem-resistant Acinetobacter baumannii (CRAB) is a persistent nosocomial pathogen that poses a significant threat to global public health, particularly…”
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Global emergence of a hypervirulent carbapenem-resistant Escherichia coli ST410 clone by Ba, Xiaoliang, Guo, Yingyi, Moran, Robert A., Doughty, Emma L., Liu, Baomo, Yao, Likang, Li, Jiahui, He, Nanhao, Shen, Siquan, Li, Yang, van Schaik, Willem, McNally, Alan, Holmes, Mark A., Zhuo, Chao

“…Carbapenem-resistant Escherichia coli (CREC) ST410 has recently emerged as a major global health problem. Here, we report a shift in CREC prevalence in Chinese…”
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Culture-independent detection and characterisation of Mycobacterium tuberculosis and M. africanum in sputum samples using shotgun metagenomics on a benchtop sequencer by Doughty, Emma L, Sergeant, Martin J, Adetifa, Ifedayo, Antonio, Martin, Pallen, Mark J

“…Tuberculosis remains a major global health problem. Laboratory diagnostic methods that allow effective, early detection of cases are central to management of…”
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Whole-genome sequencing illuminates the evolution and spread of multidrug-resistant tuberculosis in Southwest Nigeria by Senghore, Madikay, Otu, Jacob, Witney, Adam, Gehre, Florian, Doughty, Emma L, Kay, Gemma L, Butcher, Phillip, Salako, Kayode, Kehinde, Aderemi, Onyejepu, Nneka, Idigbe, Emmanuel, Corrah, Tumani, de Jong, Bouke, Pallen, Mark J, Antonio, Martin

“…Nigeria has an emerging problem with multidrug-resistant tuberculosis (MDR-TB). Whole-genome sequencing was used to understand the epidemiology of tuberculosis…”
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TheiaEuk: a species-agnostic bioinformatics workflow for fungal genomic characterization by Ambrosio, Frank J., Scribner, Michelle R., Wright, Sage M., Otieno, James R., Doughty, Emma L., Gorzalski, Andrew, Siao, Danielle Denise, Killian, Steve, Hua, Chi, Schneider, Emily, Tran, Michael, Varghese, Vici, Libuit, Kevin G., Pandori, Mark, Sevinsky, Joel R., Hess, David

“…Introduction The clinical incidence of antimicrobial-resistant fungal infections has dramatically increased in recent years. Certain fungal pathogens colonize…”
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Estimating the time-varying reproduction number of SARS-CoV-2 using national and subnational case counts by Abbott, Sam, Hellewell, Joel, Thompson, Robin N., Sherratt, Katharine, Gibbs, Hamish P., Bosse, Nikos I., Munday, James D., Meakin, Sophie, Doughty, Emma L., Chun, June Young, Chan, Yung-Wai Desmond, Finger, Flavio, Campbell, Paul, Endo, Akira, Pearson, Carl A. B., Gimma, Amy, Russell, Tim, Flasche, Stefan, Kucharski, Adam J., Eggo, Rosalind M., Funk, Sebastian

“…Background: Interventions are now in place worldwide to reduce transmission of the novel coronavirus. Assessing temporal variations in transmission in…”
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Transferable Acinetobacter baumannii plasmid pDETAB2 encodes OXA-58 and NDM-1 and represents a new class of antibiotic resistance plasmids by Liu, Haiyang, Moran, Robert A, Chen, Ying, Doughty, Emma L, Hua, Xiaoting, Jiang, Yan, Xu, Qingye, Zhang, Linghong, Blair, Jessica M A, McNally, Alan, van Schaik, Willem, Yu, Yunsong

“…Abstract Objectives To characterize a blaOXA-58- and blaNDM-1-containing MDR plasmid from a rare Acinetobacter baumannii lineage and compare it with related…”
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Evolution and dissemination of L and M plasmid lineages carrying antibiotic resistance genes in diverse Gram-negative bacteria by Blackwell, Grace A., Doughty, Emma L., Moran, Robert A.

“…Conjugative, broad host-range plasmids of the L/M complex have been associated with antibiotic resistance since the 1970s. They are found in Gram-negative…”
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Extended-Spectrum β-Lactamase Genes Traverse the Escherichia coli Populations of Intensive Care Unit Patients, Staff, and Environment by Moran, Robert A, Baomo, Liu, Doughty, Emma L, Guo, Yingyi, Ba, Xiaoliang, van Schaik, Willem, Zhuo, Chao, McNally, Alan

“…Over a 3-month period, we monitored the population of extended-spectrum β-lactam-resistant Escherichia coli (ESBL-EC) associated with the patients, staff, and…”
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Endemicity and diversification of carbapenem-resistant Acinetobacter baumannii in an intensive care unit by Doughty, Emma L., Liu, Haiyang, Moran, Robert A., Hua, Xiaoting, Ba, Xiaoliang, Guo, Feng, Chen, Xiangping, Zhang, Linghong, Holmes, Mark, van Schaik, Willem, McNally, Alan, Yu, Yunsong

“…Carbapenem-resistant Acinetobacter baumannii (CRAB) is a major public health concern globally. Often studied in the context of hospital outbreaks, little is…”
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GR13-type plasmids in Acinetobacter potentiate the accumulation and horizontal transfer of diverse accessory genes by Moran, Robert A., Liu, Haiyang, Doughty, Emma L., Hua, Xiaoting, Cummins, Elizabeth A., Liveikis, Tomas, McNally, Alan, Zhou, Zhihui, van Schaik, Willem, Yu, Yunsong

“…Carbapenem and other antibiotic resistance genes (ARGs) can be found in plasmids in Acinetobacter , but many plasmid types in this genus have not been…”
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Transmission of Staphylococcus aureus from Humans to Green Monkeys in The Gambia as Revealed by Whole-Genome Sequencing by Senghore, Madikay, Bayliss, Sion C, Kwambana-Adams, Brenda A, Foster-Nyarko, Ebenezer, Manneh, Jainaba, Dione, Michel, Badji, Henry, Ebruke, Chinelo, Doughty, Emma L, Thorpe, Harry A, Jasinska, Anna J, Schmitt, Christopher A, Cramer, Jennifer D, Turner, Trudy R, Weinstock, George, Freimer, Nelson B, Pallen, Mark J, Feil, Edward J, Antonio, Martin

“…Staphylococcus aureus is an important pathogen of humans and animals. We genome sequenced 90 S. aureus isolates from The Gambia: 46 isolates from invasive…”
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Accelerating bioinformatics implementation in public health by Libuit, Kevin G, Doughty, Emma L, Otieno, James R, Ambrosio, Frank, Kapsak, Curtis J, Smith, Emily A, Wright, Sage M, Scribner, Michelle R, Petit Iii, Robert A, Mendes, Catarina Inês, Huergo, Marcela, Legacki, Gregory, Loreth, Christine, Park, Daniel J, Sevinsky, Joel R

“…We have adopted an open bioinformatics ecosystem to address the challenges of bioinformatics implementation in public health laboratories (PHLs)…”
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Estimating the time-varying reproduction number of SARS-CoV-2 using national and subnational case counts by Abbott, Sam, Hellewell, Joel, Thompson, Robin N., Sherratt, Katharine, Gibbs, Hamish P., Bosse, Nikos I., Munday, James D., Meakin, Sophie, Doughty, Emma L., Chun, June Young, Chan, Yung-Wai Desmond, Finger, Flavio, Campbell, Paul, Endo, Akira, Pearson, Carl A. B., Gimma, Amy, Russell, Tim, Flasche, Stefan, Kucharski, Adam J., Eggo, Rosalind M., Funk, Sebastian

“…Background: Assessing temporal variations in transmission in different countries is essential for monitoring the epidemic, evaluating the effectiveness of…”
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Application of Whole Genome Sequencing and Metagenomics for Diagnosis of Tuberculosis by Doughty, Emma L

“…Globally, tuberculosis kills more people than any other infectious disease. Control of the epidemic is impeded by poor diagnostic approaches. My original…”
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