Search Results - "Dougherty, W."
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1
Intestinal bacteria and colorectal cancer: etiology and treatment
Published in Gut microbes (31-12-2023)“…The etiology of colorectal cancer (CRC) is influenced by bacterial communities that colonize the gastrointestinal tract. These microorganisms derive essential…”
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2
Campylobacter jejuni promotes colorectal tumorigenesis through the action of cytolethal distending toxin
Published in Gut (01-02-2019)“…produces a genotoxin, cytolethal distending toxin (CDT), which has DNAse activity and causes DNA double-strand breaks. Although infection has been shown to…”
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3
Shining a Light on Colibactin Biology
Published in Toxins (12-05-2021)“…Colibactin is a secondary metabolite encoded by the gene island identified in several Enterobacteriaceae, including some pathogenic ( ) commonly enriched in…”
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4
Monounsaturated fats from plant and animal sources in relation to risk of coronary heart disease among US men and women
Published in The American journal of clinical nutrition (01-03-2018)“…Monounsaturated fatty acids (MUFAs) improve blood lipid profiles in intervention studies, but prospective evidence with regard to MUFA intake and coronary…”
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5
Loss-of-Function GAS8 Mutations Cause Primary Ciliary Dyskinesia and Disrupt the Nexin-Dynein Regulatory Complex
Published in American journal of human genetics (01-10-2015)“…Multiciliated epithelial cells protect the upper and lower airways from chronic bacterial infections by moving mucus and debris outward. Congenital disorders…”
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6
Motility of efferent duct cilia aids passage of sperm cells through the male reproductive system
Published in Molecular human reproduction (27-02-2021)“…Motile cilia line the efferent ducts of the mammalian male reproductive tract. Several recent mouse studies have demonstrated that a reduced generation of…”
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7
Imaging of Glial Cell Activation and White Matter Integrity in Brains of Active and Recently Retired National Football League Players
Published in JAMA neurology (01-01-2017)“…Microglia, the resident immune cells of the central nervous system, play an important role in the brain's response to injury and neurodegenerative processes…”
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8
Ciliary beat pattern and frequency in genetic variants of primary ciliary dyskinesia
Published in The European respiratory journal (01-12-2014)“…Primary ciliary dyskinesia (PCD) is a rare genetic disorder leading to recurrent respiratory tract infections. High-speed video-microscopy analysis (HVMA) of…”
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SPEF2- and HYDIN -Mutant Cilia Lack the Central Pair-associated Protein SPEF2, Aiding Primary Ciliary Dyskinesia Diagnostics
Published in American journal of respiratory cell and molecular biology (01-03-2020)“…Primary ciliary dyskinesia (PCD) is a genetically heterogeneous chronic destructive airway disease. PCD is traditionally diagnosed by nasal nitric oxide…”
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10
Networking behaviors and career outcomes: differences for men and women?
Published in Journal of organizational behavior (01-05-2004)“…Engaging in networking behaviors, by attempting to develop and maintain relationships with others who have the potential to provide work or career assistance,…”
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11
Gut microbiota maturation during early human life induces enterocyte proliferation via microbial metabolites
Published in BMC microbiology (11-07-2020)“…The intestinal tract undergoes a period of cellular maturation during early life, primarily characterized by the organization of epithelial cells into…”
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12
Spiking Improved Solution Phosphorus-31 Nuclear Magnetic Resonance Identification of Soil Phosphorus Compounds
Published in Soil Science Society of America journal (01-05-2009)“…Chemical characterization of soil organic P using 31P nuclear magnetic resonance (NMR) spectroscopy relies on the correct assignment of resonances. We examined…”
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13
Ciliary function and motor protein composition of human fallopian tubes
Published in Human reproduction (Oxford) (01-12-2015)“…STUDY QUESTION What is the motor protein composition and function of human fallopian tube (FT) cilia? SUMMARY ANSWER Although the motor protein composition and…”
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14
Mitochondrial transcription factor A in RORγt+ lymphocytes regulate small intestine homeostasis and metabolism
Published in Nature communications (22-07-2021)“…RORγt + lymphocytes, including interleukin 17 (IL-17)-producing gamma delta T (γδT17) cells, T helper 17 (Th17) cells, and group 3 innate lymphoid cells…”
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15
The microbial genotoxin colibactin exacerbates mismatch repair mutations in colorectal tumors
Published in Neoplasia (New York, N.Y.) (01-09-2023)“…Certain Enterobacteriaceae strains contain a 54-kb biosynthetic gene cluster referred to as “pks” encoding the biosynthesis of a secondary metabolite,…”
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16
TTC25 Deficiency Results in Defects of the Outer Dynein Arm Docking Machinery and Primary Ciliary Dyskinesia with Left-Right Body Asymmetry Randomization
Published in American journal of human genetics (04-08-2016)“…Multiprotein complexes referred to as outer dynein arms (ODAs) develop the main mechanical force to generate the ciliary and flagellar beat. ODA defects are…”
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Homozygous loss-of-function mutations in MNS1 cause laterality defects and likely male infertility
Published in PLoS genetics (27-08-2018)“…The clinical spectrum of ciliopathies affecting motile cilia spans impaired mucociliary clearance in the respiratory system, laterality defects including heart…”
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Is the development of desalination compatible with sustainable development of the Arabian Gulf?
Published in Marine pollution bulletin (01-12-2021)“…The development of desalination has been essential to the rapid economic development of the countries bordering the Arabian Gulf. The current production…”
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Substance Use and Addiction in Athletes: The Case for Neuromodulation and Beyond
Published in International journal of environmental research and public health (01-12-2022)“…Substance use, misuse and use disorders continue to be major problems in society as a whole and athletes are certainly not exempt. Substance use has surrounded…”
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Rapid decomposition of phytate applied to a calcareous soil demonstrated by a solution ³¹P NMR study
Published in European journal of soil science (01-08-2010)“…myo-Inositol hexakisphosphate (phytate) is widely regarded as an abundant form of soil organic phosphorus (P) in many soils. Its abundance is believed to be…”
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