Search Results - "Dougherty, P"

Intraepidermal nerve fiber loss corresponds to the development of Taxol-induced hyperalgesia and can be prevented by treatment with minocycline by Boyette-Davis, J., Xin, W., Zhang, H., Dougherty, P.M.

“…Loss of intraepidermal nerve fibers (IENFs) has been speculated to play a critical role in the development of various neuropathies. In this study, the density…”
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Clinical and preclinical perspectives on Chemotherapy-Induced Peripheral Neuropathy (CIPN): a narrative review by Flatters, S.J.L., Dougherty, P.M., Colvin, L.A.

“…This review provides an update on the current clinical and preclinical understanding of chemotherapy induced peripheral neuropathy (CIPN). The overview of the…”
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Protection against oxaliplatin-induced mechanical hyperalgesia and intraepidermal nerve fiber loss by minocycline by Boyette-Davis, J., Dougherty, P.M.

“…Treatment with the chemotherapeutic agent oxaliplatin produces a robust painful neuropathy similar to various other neuropathic conditions which result in loss…”
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Astrocytes, but not microglia, are activated in oxaliplatin and bortezomib-induced peripheral neuropathy in the rat by Robinson, C.R, Zhang, H, Dougherty, P.M

“…Highlights • Chemotherapy causes mechanical hypersensitivity and activated astrocytes. • Microglia were not activated by chemotherapy but were by spinal nerve…”
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Pharmaceutical therapies to recode nonsense mutations in inherited diseases by Lee, Hui-Ling Rose, Dougherty, Joseph P

“…Nonsense codons, generated from nonsense mutations or frameshifts, contribute significantly to the spectrum of inherited human diseases such as cystic…”
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Minocycline blocks lipopolysaccharide induced hyperalgesia by suppression of microglia but not astrocytes by Yoon, S.-Y, Patel, D, Dougherty, P.M

“…Highlights ► LPS hyperalgesia involves activation of microglial/macrophage activity in DRG and spinal cord. ► LPS-induced hyperalgesia is inhibited by…”
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Survey of Voyager plasma science ions at Jupiter: 3. Protons and minor ions by Bodisch, K. M., Dougherty, L. P., Bagenal, F.

“…When the Voyager 1 and 2 spacecraft flew through the Jovian system in March and July 1979, the Plasma Science instruments measured ions and electrons in the Io…”
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Comparing Lifestyle Modifications and the Magnitude of Their Associated Benefit on Cancer Mortality by Dougherty, Timothy P, Meyer, Joshua E

“…Many cancers are associated with poor diet, lack of physical activity, and excess weight. Improving any of these three lifestyle factors would likely reduce…”
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Protein Phosphatase 1 Down Regulates ZYG-1 Levels to Limit Centriole Duplication by Peel, Nina, Iyer, Jyoti, Naik, Anar, Dougherty, Michael P, Decker, Markus, O'Connell, Kevin F

“…In humans perturbations of centriole number are associated with tumorigenesis and microcephaly, therefore appropriate regulation of centriole duplication is…”
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Heterodimeric Bispecific Single Chain Variable Fragments (scFv) Killer Engagers (BiKEs) Enhance NK-cell Activity Against CD133+ Colorectal Cancer Cells by Schmohl, J. U., Gleason, M. K., Dougherty, P. R., Miller, J. S., Vallera, D. A.

“…Background Natural killer (NK) cells are potent cytotoxic lymphocytes that play a critical role in tumor immunosurveillance and control. Cancer stem cells…”
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Survey of Voyager plasma science ions at Jupiter: 1. Analysis method by Bagenal, F., Dougherty, L. P., Bodisch, K. M., Richardson, J. D., Belcher, J. M.

“…The Voyagers 1 and 2 spacecraft flew by Jupiter in March and July of 1979, respectively. The Plasma Science instrument (PLS) acquired detailed measurements of…”
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Changes in sensory processing in the spinal dorsal horn accompany vincristine-induced hyperalgesia and allodynia by WENG, H.-R, CORDELLA, J. V, DOUGHERTY, P. M

“…Abnormal sensation and pain are major dose-limiting factors in cancer chemotherapy with vincristine. In this study, we have adapted a model of this condition…”
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Peripheral neuropathic pain: signs, symptoms, mechanisms, and causes: are they linked? by Colvin, L.A., Dougherty, P.M.

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Core Stability and Its Relationship to Lower Extremity Function and Injury by Willson, John D, Dougherty, Christopher P, Ireland, Mary Lloyd, Davis, Irene McClay

“…Mr. Willson is Research Assistant, University of Delaware, Newark, DE. Dr. Dougherty is in private practice at Missouri Orthopedics and Sports Medicine,…”
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Spinal astrocyte gap junction and glutamate transporter expression contributes to a rat model of bortezomib-induced peripheral neuropathy by Robinson, C.R, Dougherty, P.M

“…Highlights • Bortezomib hyperalgesia is prevented by minocycline, carbenoxolone, and ceftriaxone. • Spinal GFAP expression is increased in rats with bortezomib…”
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The Universe We Think In by James V. Schall by Dougherty, Jude P

“…This paper is a review of the book: James V. Schall, The Universe We Think In (Washington, D.C.: The Catholic University of America Press, 2019). The author…”
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Western Culture: A Collective Achievement by Dougherty, Jude P

“…By examining selected works by Stephen Gaukroger, Alfred North Whitehead, Lynn White, Jr., Benjamin Farrington, and Paul Gans, the author discusses the…”
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Walter Kaufmann: Philosopher, Humanist, Heretic by Stanley Corngold by Dougherty, Jude P

“…This paper is a review of the book: Stanley Corngold, Walter Kaufmann: Philosopher, Humanist, Heretic (Princeton: Princeton University Press, 2018). The author…”
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Pharmacological and behavioral characterization of the 5-HT2A receptor in C57BL/6N mice by Dougherty, John P., Aloyo, Vincent J.

“…Rationale The serotonin (5-HT) 2A receptor is implicated in numerous psychiatric disorders, making it an important, clinically relevant target. Despite the…”
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Altered discharges of spinal wide dynamic range neurons and down-regulation of glutamate transporter expression in rats with paclitaxel-induced hyperalgesia by Cata, J.P., Weng, H.-R., Chen, J.-H., Dougherty, P.M.

“…Changes in the signaling of wide dynamic range neurons and the expression of glutamate transporters in the lumbar spinal dorsal horn of rats with Taxol-induced…”
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