Search Results - "Dougherty, Jonathan D."
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FAM134B, the Selective Autophagy Receptor for Endoplasmic Reticulum Turnover, Inhibits Replication of Ebola Virus Strains Makona and Mayinga
Published in The Journal of infectious diseases (15-10-2016)“…Selective autophagy of the endoplasmic reticulum (termed ER-phagy) is controlled by members of the FAMI34 reticulon protein family. Here we used mouse…”
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Poliovirus-Mediated Disruption of Cytoplasmic Processing Bodies
Published in Journal of Virology (01-01-2011)“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Multiple Poliovirus Proteins Repress Cytoplasmic RNA Granules
Published in Viruses (25-11-2015)“…We have previously shown that poliovirus (PV) infection induces stress granule (SG) formation early in infection and then inhibits the formation of SG and…”
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A Systems Approach Reveals MAVS Signaling in Myeloid Cells as Critical for Resistance to Ebola Virus in Murine Models of Infection
Published in Cell reports (Cambridge) (17-01-2017)“…The unprecedented 2013–2016 outbreak of Ebola virus (EBOV) resulted in over 11,300 human deaths. Host resistance to RNA viruses requires RIG-I-like receptor…”
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mRNA Decapping Enzyme 1a (Dcp1a)-induced Translational Arrest through Protein Kinase R (PKR) Activation Requires the N-terminal Enabled Vasodilator-stimulated Protein Homology 1 (EVH1) Domain
Published in The Journal of biological chemistry (14-02-2014)“…We have shown previously that poliovirus infection disrupts cytoplasmic P-bodies in infected mammalian cells. During the infectious cycle, poliovirus causes…”
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Alisporivir Has Limited Antiviral Effects Against Ebola Virus Strains Makona and Mayinga
Published in The Journal of infectious diseases (15-10-2016)“…Antiviral therapeutics with existing clinical safely profiles would be highly desirable in an outbreak situation, such as the 2013-2016 emergence of Ebola…”
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