Search Results - "Dougherty, Darin D."

A Randomized Sham-Controlled Trial of Deep Brain Stimulation of the Ventral Capsule/Ventral Striatum for Chronic Treatment-Resistant Depression by Dougherty, Darin D, Rezai, Ali R, Carpenter, Linda L, Howland, Robert H, Bhati, Mahendra T, O’Reardon, John P, Eskandar, Emad N, Baltuch, Gordon H, Machado, Andre D, Kondziolka, Douglas, Cusin, Cristina, Evans, Karleyton C, Price, Lawrence H, Jacobs, Karen, Pandya, Mayur, Denko, Timothey, Tyrka, Audrey R, Brelje, Tim, Deckersbach, Thilo, Kubu, Cynthia, Malone, Donald A

“…Abstract Background Multiple open-label trials of deep brain stimulation (DBS) for treatment-resistant depression (TRD), including those targeting the ventral…”
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Mapping the subcortical connectivity of the human default mode network by Li, Jian, Curley, William H., Guerin, Bastien, Dougherty, Darin D., Dalca, Adrian V., Fischl, Bruce, Horn, Andreas, Edlow, Brian L.

“…The default mode network (DMN) mediates self-awareness and introspection, core components of human consciousness. Therapies to restore consciousness in…”
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Closing the Loop on Deep Brain Stimulation for Treatment-Resistant Depression by Widge, Alik S, Malone, Jr, Donald A, Dougherty, Darin D

“…Major depressive episodes are the largest cause of psychiatric disability, and can often resist treatment with medication and psychotherapy. Advances in the…”
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Local and distant responses to single pulse electrical stimulation reflect different forms of connectivity by Crocker, Britni, Ostrowski, Lauren, Williams, Ziv M., Dougherty, Darin D., Eskandar, Emad N., Widge, Alik S., Chu, Catherine J., Cash, Sydney S., Paulk, Angelique C.

“…Measuring connectivity in the human brain involves innumerable approaches using both noninvasive (fMRI, EEG) and invasive (intracranial EEG or iEEG) recording…”
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Clinical Approach to the Differential Diagnosis Between Behavioral Variant Frontotemporal Dementia and Primary Psychiatric Disorders by Ducharme, Simon, Price, Bruce H., Larvie, Mykol, Dougherty, Darin D., Dickerson, Bradford C.

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Measuring Consciousness in the Intensive Care Unit by Edlow, Brian L., Fecchio, Matteo, Bodien, Yelena G., Comanducci, Angela, Rosanova, Mario, Casarotto, Silvia, Young, Michael J., Li, Jian, Dougherty, Darin D., Koch, Christof, Tononi, Giulio, Massimini, Marcello, Boly, Melanie

“…Early reemergence of consciousness predicts long-term functional recovery for patients with severe brain injury. However, tools to reliably detect…”
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Deep Brain Stimulation of the Ventral Capsule/Ventral Striatum for Treatment-Resistant Depression by Malone, Donald A, Dougherty, Darin D, Rezai, Ali R, Carpenter, Linda L, Friehs, Gerhard M, Eskandar, Emad N, Rauch, Scott L, Rasmussen, Steven A, Machado, Andre G, Kubu, Cynthia S, Tyrka, Audrey R, Price, Lawrence H, Stypulkowski, Paul H, Giftakis, Jonathon E, Rise, Mark T, Malloy, Paul F, Salloway, Stephen P, Greenberg, Benjamin D

“…Background We investigated the use of deep brain stimulation (DBS) of the ventral capsule/ventral striatum (VC/VS) for treatment refractory depression. Methods…”
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Perturbing fMRI brain dynamics using transcranial direct current stimulation by Tu, Yiheng, Cao, Jin, Guler, Seyhmus, Chai-Zhang, Thalia, Camprodon, Joan A., Vangel, Mark, Gollub, Randy L., Dougherty, Darin D., Kong, Jian

“…The dynamic nature of resting-state functional magnetic resonance imaging (fMRI) brain activity and connectivity has drawn great interest in the past decade…”
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Brain stimulation and brain lesions converge on common causal circuits in neuropsychiatric disease by Siddiqi, Shan H., Schaper, Frederic L. W. V. J., Horn, Andreas, Hsu, Joey, Padmanabhan, Jaya L., Brodtmann, Amy, Cash, Robin F. H., Corbetta, Maurizio, Choi, Ki Sueng, Dougherty, Darin D., Egorova, Natalia, Fitzgerald, Paul B., George, Mark S., Gozzi, Sophia A., Irmen, Frederike, Kuhn, Andrea A., Johnson, Kevin A., Naidech, Andrew M., Pascual-Leone, Alvaro, Phan, Thanh G., Rouhl, Rob P. W., Taylor, Stephan F., Voss, Joel L., Zalesky, Andrew, Grafman, Jordan H., Mayberg, Helen S., Fox, Michael D.

“…Damage to specific brain circuits can cause specific neuropsychiatric symptoms. Therapeutic stimulation to these same circuits may modulate these symptoms. To…”
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Model-based navigation of transcranial focused ultrasound neuromodulation in humans: Application to targeting the amygdala and thalamus by Daneshzand, Mohammad, Guerin, Bastien, Kotlarz, Parker, Chou, Tina, Dougherty, Darin D., Edlow, Brian L., Nummenmaa, Aapo

“…Transcranial focused ultrasound (tFUS) neuromodulation has shown promise in animals but is challenging to translate to humans because of the thicker skull that…”
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CLoSES: A platform for closed-loop intracranial stimulation in humans by Zelmann, Rina, Paulk, Angelique C., Basu, Ishita, Sarma, Anish, Yousefi, Ali, Crocker, Britni, Eskandar, Emad, Williams, Ziv, Cosgrove, G. Rees, Weisholtz, Daniel S., Dougherty, Darin D., Truccolo, Wilson, Widge, Alik S., Cash, Sydney S.

“…Targeted interrogation of brain networks through invasive brain stimulation has become an increasingly important research tool as well as therapeutic modality…”
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Transcranial focused ultrasound of the amygdala modulates fear network activation and connectivity by Chou, Tina, Deckersbach, Thilo, Guerin, Bastien, Sretavan Wong, Karianne, Borron, Benjamin M., Kanabar, Anish, Hayden, Ashley N., Long, Marina P., Daneshzand, Mohammad, Pace-Schott, Edward F., Dougherty, Darin D.

“…Current noninvasive brain stimulation methods are incapable of directly modulating subcortical brain regions critically involved in psychiatric disorders…”
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Local and distant cortical responses to single pulse intracranial stimulation in the human brain are differentially modulated by specific stimulation parameters by Paulk, Angelique C., Zelmann, Rina, Crocker, Britni, Widge, Alik S., Dougherty, Darin D., Eskandar, Emad N., Weisholtz, Daniel S., Richardson, R. Mark, Cosgrove, G. Rees, Williams, Ziv M., Cash, Sydney S.

“…Electrical neuromodulation via direct electrical stimulation (DES) is an increasingly common therapy for a wide variety of neuropsychiatric diseases…”
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DISSECTING OCD CIRCUITS: FROM ANIMAL MODELS TO TARGETED TREATMENTS by Ahmari, Susanne E., Dougherty, Darin D.

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Case Report of Dual-Site Neurostimulation and Chronic Recording of Cortico-Striatal Circuitry in a Patient With Treatment Refractory Obsessive Compulsive Disorder by Olsen, Sarah T, Basu, Ishita, Bilge, Mustafa Taha, Kanabar, Anish, Boggess, Matthew J, Rockhill, Alexander P, Gosai, Aishwarya K, Hahn, Emily, Peled, Noam, Ennis, Michaela, Shiff, Ilana, Fairbank-Haynes, Katherine, Salvi, Joshua D, Cusin, Cristina, Deckersbach, Thilo, Williams, Ziv, Baker, Justin T, Dougherty, Darin D, Widge, Alik S

“…Psychiatric disorders are increasingly understood as dysfunctions of hyper- or hypoconnectivity in distributed brain circuits. A prototypical example is…”
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Functional Connectivity Between Anterior Insula and Key Nodes of Frontoparietal Executive Control and Salience Networks Distinguish Bipolar Depression From Unipolar Depression and Healthy Control Subjects by Ellard, Kristen K., Zimmerman, Jared P., Kaur, Navneet, Van Dijk, Koene R.A., Roffman, Joshua L., Nierenberg, Andrew A., Dougherty, Darin D., Deckersbach, Thilo, Camprodon, Joan A.

“…Patients with bipolar depression are characterized by dysregulation across the full spectrum of mood, differentiating them from patients with unipolar…”
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Future directions in psychiatric neurosurgery: Proceedings of the 2022 American Society for Stereotactic and Functional Neurosurgery meeting on surgical neuromodulation for psychiatric disorders by Hitti, Frederick L., Widge, Alik S., Riva-Posse, Patricio, Malone, Donald A., Okun, Michael S., Shanechi, Maryam M., Foote, Kelly D., Lisanby, Sarah H., Ankudowich, Elizabeth, Chivukula, Srinivas, Chang, Edward F., Gunduz, Aysegul, Hamani, Clement, Feinsinger, Ashley, Kubu, Cynthia S., Chiong, Winston, Chandler, Jennifer A., Carbunaru, Rafael, Cheeran, Binith, Raike, Robert S., Davis, Rachel A., Halpern, Casey H., Vanegas-Arroyave, Nora, Markovic, Dejan, Bick, Sarah K., McIntyre, Cameron C., Richardson, R. Mark, Dougherty, Darin D., Kopell, Brian H., Sweet, Jennifer A., Goodman, Wayne K., Sheth, Sameer A., Pouratian, Nader

“…Objective. Despite advances in the treatment of psychiatric diseases, currently available therapies do not provide sufficient and durable relief for as many as…”
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Deep Brain Stimulation: Clinical Applications by Dougherty, Darin D

“…Deep brain stimulation has been used for decades in neurology to treat movement disorders. More recent work has focused on developing applications for deep…”
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Microstructural abnormalities in subcortical reward circuitry of subjects with major depressive disorder by Blood, Anne J, Iosifescu, Dan V, Makris, Nikos, Perlis, Roy H, Kennedy, David N, Dougherty, Darin D, Kim, Byoung Woo, Lee, Myung Joo, Wu, Shirley, Lee, Sang, Calhoun, Jesse, Hodge, Steven M, Fava, Maurizio, Rosen, Bruce R, Smoller, Jordan W, Gasic, Gregory P, Breiter, Hans C

“…Previous studies of major depressive disorder (MDD) have focused on abnormalities in the prefrontal cortex and medial temporal regions. There has been little…”
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Case Report: Deep Brain Stimulation to the Ventral Internal Capsule/Ventral Striatum Induces Repeated Transient Episodes of Voltage-Dependent Tourette-Like Behaviors by Camprodon, Joan A, Chou, Tina, Testo, Abigail A, Deckersbach, Thilo, Scharf, Jeremiah M, Dougherty, Darin D

“…Deep Brain Stimulation (DBS) is an invasive device-based neuromodulation technique that allows the therapeutic direct stimulation of subcortical and deep…”
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