Search Results - "Doudet, Doris J."

Evaluation of microglia activation related markers following a clinical course of TBS: A non-human primate study by Aceves-Serrano, Lucero, Neva, Jason L, Munro, Jonathan, Vavasour, Irene M, Parent, Martin, Boyd, Lara A, Doudet, Doris J

“…While the applicability and popularity of theta burst stimulation (TBS) paradigms remain, current knowledge of their neurobiological effects is still limited,…”
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Insight Into the Effects of Clinical Repetitive Transcranial Magnetic Stimulation on the Brain From Positron Emission Tomography and Magnetic Resonance Imaging Studies: A Narrative Review by Aceves-Serrano, Lucero, Neva, Jason L, Doudet, Doris J

“…Repetitive transcranial magnetic stimulation (rTMS) has been proposed as a therapeutic tool to alleviate symptoms for neurological and psychiatric diseases…”
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fMRI in Non-human Primate: A Review on Factors That Can Affect Interpretation and Dynamic Causal Modeling Application by Jovellar, D. Blair, Doudet, Doris J.

“…Dynamic causal modeling (DCM)—a framework for inferring hidden neuronal states from brain activity measurements (e. g., fMRI) and their context-dependent…”
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Direct intranigral administration of an ubiquitin proteasome system inhibitor in rat: Behavior, positron emission tomography, immunohistochemistry by Mackey, Scott, Jing, Yu, Flores, Joseph, Dinelle, Katie, Doudet, Doris J.

“…Several independent lines of research suggest that disruption of the ubiquitin proteasome system (UPS) may play a role in the pathophysiology of Parkinson's…”
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Letter to the editor: Chronic theta burst stimulation does not significantly modulate glial activity in the healthy non-human primate brain by Aceves-Serrano, Lucero, Andrushko, Justin W., Neva, Jason L., Boyd, Lara A., Doudet, Doris J.

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Dipeptidyl Peptidase IV Inhibition With MK0431 Improves Islet Graft Survival in Diabetic NOD Mice Partially via T-Cell Modulation by KIM, Su-Jin, NIAN, Cuilan, DOUDET, Doris J, MCINTOSH, Christopher H. S

“…Dipeptidyl Peptidase IV Inhibition With MK0431 Improves Islet Graft Survival in Diabetic NOD Mice Partially via T-Cell Modulation Su-Jin Kim 1 , Cuilan Nian 1…”
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Combined In Vivo Microdialysis and PET Studies to Validate [ 11 C]Yohimbine Binding as a Marker of Noradrenaline Release by Landau, Anne Marlene, Jakobsen, Steen, Thomsen, Majken Borup, Alstrup, Aage Kristian Olsen, Orlowski, Dariusz, Jacobsen, Jan, Wegener, Gregers, Mørk, Arne, Sørensen, Jens Christian Hedemann, Doudet, Doris J

“…The noradrenaline system attracts attention for its role in mood disorders and neurodegenerative diseases but the lack of well-validated methods impairs our…”
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Inhibition of Dipeptidyl Peptidase IV With Sitagliptin (MK0431) Prolongs Islet Graft Survival in Streptozotocin-Induced Diabetic Mice by KIM, Su-Jin, CUILAN NIAN, DOUDET, Doris J, MCLNTOSH, Christopher H. S

“…Inhibition of Dipeptidyl Peptidase IV With Sitagliptin (MK0431) Prolongs Islet Graft Survival in Streptozotocin-Induced Diabetic Mice Su-Jin Kim 1 , Cuilan…”
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Quantification of [11C]yohimbine Binding to α2 Adrenoceptors in Rat Brain in vivo by Phan, Jenny-Ann, Landau, Anne M, Wong, Dean F, Jakobsen, Steen, Nahimi, Adjmal, Doudet, Doris J, Gjedde, Albert

“…We quantified the binding potentials (BPND) of [11C]yohimbine binding in rat brain to alpha-2 adrenoceptors to evaluate [11C]yohimbine as an in vivo marker of…”
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Imaging of enzyme replacement therapy using PET by Phenix, Christopher P, Rempel, Brian P, Colobong, Karen, Doudet, Doris J, Adam, Michael J, Clarke, Lorne A, Withers, Stephen G

“…Direct enzyme replacement therapy (ERT) has been introduced as a means to treat a number of rare, complex genetic conditions associated with lysosomal…”
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Quantitative micro positron emission tomography (PET) imaging for the in vivo determination of pancreatic islet graft survival by McIntosh, Christopher H S, Kim, Su-Jin, Doudet, Doris J, Studenov, Andrei R, Nian, Cuilan, Ruth, Thomas J, Gambhir, Sanjiv Sam

“…Islet transplantation is an attractive approach for treating type-1 diabetes, but there is a massive loss of transplanted islets. It is currently only possible…”
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Continuous but not intermittent theta burst stimulation decreases striatal dopamine release and cortical excitability by Aceves-Serrano, Lucero, Neva, Jason L., Munro, Jonathan, Parent, Martin, Boyd, Lara A., Doudet, Doris J.

“…Dopamine modulation is thought to underpin some of the therapeutic effects associated with repetitive transcranial magnetic stimulation (rTMS). However,…”
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Comparison of Invasive and Non-invasive Estimation of [11C]PBR28 Binding in Non-human Primates by Aceves-Serrano, Lucero, Sossi, Vesna, Doudet, Doris J.

“…Purpose To identify a reliable alternative to the full blood [ 11 C]PBR28 quantification method that would be easily replicated in multiple research and…”
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Pathological gambling: Relation of skin conductance response to dopaminergic neurotransmission and sensation-seeking by Peterson, Ericka, Møller, Arne, Doudet, Doris J, Bailey, Christopher J, Hansen, Kim Vang, Rodell, Anders, Linnet, Jakob, Gjedde, Albert

“…Abstract Absent Skin Conductance Response (SCR) in pathological gambling (PG) may relate to dopaminergic mechanisms. We recruited equal numbers of PG subjects…”
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Modulation of Abnormal Metabolic Brain Networks by Experimental Therapies in a Nonhuman Primate Model of Parkinson Disease: An Application to Human Retinal Pigment Epithelial Cell Implantation by Peng, Shichun, Ma, Yilong, Flores, Joseph, Cornfeldt, Michael, Mitrovic, Branka, Eidelberg, David, Doudet, Doris J

“…Abnormal covariance pattern of regional metabolism associated with Parkinson disease (PD) is modulated by dopaminergic pharmacotherapy. Using high-resolution…”
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A Reversible Tracer Analysis Approach to the Study of Effective Dopamine Turnover by Sossi, Vesna, Doudet, Doris J., Holden, James E.

“…Changes in dopamine turnover resulting from disease states such as Parkinson's disease may be reflected in corresponding changes in the kinetics of the…”
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Elevated dopamine D1 receptor availability in striatum of Göttingen minipigs after electroconvulsive therapy by Landau, Anne M, Alstrup, Aage KO, Audrain, Helene, Jakobsen, Steen, Simonsen, Mette, Møller, Arne, Videbech, Poul, Wegener, Gregers, Gjedde, Albert, Doudet, Doris J

“…Electroconvulsive therapy (ECT), a direct form of brain stimulation, is an effective antidepressant. We hypothesized that the beneficial effects of ECT are…”
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Nigrostriatal proteasome inhibition impairs dopamine neurotransmission and motor function in minipigs by Lillethorup, Thea P., Glud, Andreas N., Alstrup, Aage K.O., Mikkelsen, Trine W., Nielsen, Erik H., Zaer, Hamed, Doudet, Doris J., Brooks, David J., Sørensen, Jens Christian H., Orlowski, Dariusz, Landau, Anne M.

“…Parkinson's disease (PD) is characterized by degeneration of dopaminergic neurons in the substantia nigra leading to slowness and stiffness of limb movement…”
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Intracerebroventricular Corticotropin-Releasing Factor Increases Limbic Glucose Metabolism and Has Social Context-Dependent Behavioral Effects in Nonhuman Primates by Strome, Elissa M., G. H. Trevor Wheler, Higley, J. Dee, Loriaux, D. Lynn, Suomi, Stephen J., Doudet, Doris J.

“…Corticotropin-releasing factor (CRF) is a neuropeptide involved in integrating the behavioral, autonomic, and hormonal responses to stress within the central…”
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Quantitative in vitro phosphor imaging using [3H] and [18F] radioligands: the effects of chronic desipramine treatment on serotonin 5-HT2 receptors by Strome, Elissa M, Jivan, Salma, Doudet, Doris J

“…Traditionally, autoradiography of neuroreceptors is performed in vitro using tritiated ligands and low sensitivity X-ray film, requiring long exposure times…”
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