Search Results - "Doudet, D"

Dopamine release in ventral striatum of pathological gamblers losing money by Linnet, J., Peterson, E., Doudet, D. J., Gjedde, A., Møller, A.

“…Linnet J, Peterson E, Doudet DJ, Gjedde A, Møller A. Dopamine release in ventral striatum of pathological gamblers losing money. Objective:  To investigate…”
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Role of ICAM-1 in persisting inflammation in Parkinson disease and MPTP monkeys by Miklossy, J., Doudet, D.D., Schwab, C., Yu, S., McGeer, E.G., McGeer, P.L.

“…It has been established that neuroinflammation is present in the substantia nigra (SN) of Parkinson disease (PD) cases but the factors responsible are as yet…”
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Pten (phosphatase and tensin homologue gene) haploinsufficiency promotes insulin hypersensitivity by Wong, J. T, Kim, P. T. W, Peacock, J. W, Yau, T. Y, Mui, A. L.-F, Chung, S. W, Sossi, V, Doudet, D, Green, D, Ruth, T. J, Parsons, R, Verchere, C. B, Ong, C. J

“…Aims/hypothesis Insulin controls glucose metabolism via multiple signalling pathways, including the phosphatidylinositol 3-kinase (PI3K) pathway in muscle and…”
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PET imaging of implanted human retinal pigment epithelial cells in the MPTP-induced primate model of Parkinson's disease by Doudet, D.J., Cornfeldt, M.L., Honey, C.R., Schweikert, A.W., Allen, R.C.

“…Human retinal pigment epithelial (hRPE) cells produce l-dopa, are easily harvested and expanded in culture, and, attached to microcarriers, can survive in the…”
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Neurodegenerative disease by Doudet, D J

“…Issue Title: Special Issue: Molecular Imaging in the Evaluation of Neurodegenerative Diseases…”
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Preclinical studies of clinical courses of TBS at UBC by Doudet, D.

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Neuromodulation in a minipig MPTP model of Parkinson disease by Bjarkam, C. R., Nielsen, M. S., Glud, A. N., Rosendal, F., Mogensen, P., Bender, D., Doudet, D., Møller, A., Sørensen, J. C.

“…Large animal neuroscience enables the use of conventional clinical brain imagers and the direct use and testing of surgical procedures and equipment from the…”
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Comparison of reference-tissue methods for quantifying the binding of [ 11C]raclopride and [ 11C]NMSP in rat microPET studies by Østergaard, Søren D., Pedersen, K., Gjedde, A., Doudet, D.

“…Introduction The employment of dopamine D2-like receptor ligands in PET studies of behavioural, physiological and pharmacological effects on dopaminergic…”
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Dopamine and skin conductance response to gambling by Peterson, Ericka, Moeller, A., Linnet, J., Doudet, D., Hansen, K.V., Rodell, A., Gjedde, Albert

“…The role of SCR in relation to the dopamine system is important, as individuals suffering from addictive behaviors show abnormal behavior both in the SCR and…”
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Presynaptic Dopaminergic Deficits in Lesch–Nyhan Disease by Ernst, Monique, Zametkin, Alan J, Matochik, John A, Pascualvaca, Daisy, Jons, Peter H, Hardy, Kristina, Hankerson, James G, Doudet, Doris J, Cohen, Robert M

“…Lesch–Nyhan disease, a rare X-linked recessive disorder of purine synthesis, is characterized by the virtual absence of hypoxanthine–guanine…”
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Human vs Non human primates: practical tips by Aceves, L., Doudet, D.

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Evaluation of Dopaminergic Presynaptic Integrity: 6-[18F]Fluoro-L-Dopa Versus 6-[18F]Fluoro-L-m-Tyrosine by Doudet, D. J., Chan, G. L.-Y., Jivan, S., DeJesus, O. T., McGeer, E. G., English, C., Ruth, T. J., Holden, J. E.

“…The effectiveness of 6-[18F]fluoro-L-m-tyrosine (6FMT) to evaluate dopamine presynaptic integrity was compared to that of 6-[18F]fluoro-L-dopa (6FDOPA) in vivo…”
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P2.014 Gait analysis in a porcine model of progressive Parkinson disease established by chronic 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) intoxication by Mogensen, P, Nielsen, M.S, Glud, A.N, Møller, A, Bender, D, Doudet, D, Sørensen, J.C, Bjarkam, C.R

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3.122 Long term effects of implants of human retinal pigment epithelial cells on gelatin microcarriers (hRPE-GM) (Spheramine®) in MPTP-treated primates: Behavior and PET imaging by Doudet, D, Flores, J, O'Kusky, J, Mitrovic, B, Cornfeldt, M

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In-vivo occupancy studies with rat DTBZ+ data using a microPET® Focus 120 by Sossi, Vesna, Holden, J., Camborde, M.L., Kornelson, R., McCormick, S., Green, J., Studenov, A., Ruth, T., Doudet, D.

“…Attenuation and scatter corrected images were realigned to a digitized brain atlas (Rubins et al., 2003) used as guidance when placing regions of interest…”
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3.018 Survival and host immune response of implants of human retinal pigment epithelial cells on gelatin microcarriers (hRPE-GM) (Spheramine®) in animal models of Parkinson's disease (PD) by Flores, J, O'Kusky, J, Russ, K, Cornfeldt, M, Mitrovic, B, Doudet, D

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3.202 Survival and host immune response of implants of human retinal pigment epithelial cells on gelatin microcarriers (hRPE-GM) (Spheramine®) in animal models of Parkinson's disease (PD) by Flores, J, O'Kusky, J, Russ, K, Cornfeldt, M, Mitrovic, B, Doudet, D

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MRI and PET studies of manganese-intoxicated monkeys by SHINOTOH, H, SNOW, B. J, HEWITT, K. A, PATE, B. D, DOUDET, D, NUGENT, R, PERL, D. P, OLANOW, W, CALNE, D. B

“…Using MRI and PET, we investigated the consequences of manganese intoxication in a primate model of parkinsonism and dystonia. Three rhesus monkeys were…”
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Noradrenaline release: Potential antidepressant mechanism of brain stimulation? by Doudet, D.J., Dyve, S., Alstrup, A.K.O., Jakobsen, S., Simonsen, M., Moller, A., Videbech, Wegener, G., Gjedde, A., Landau, A.M.

“…Electroconvulsive therapy (ECT), a direct form of electrical brain stimulation, is the most effective antidepressant therapy known…”
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Stereotaxic intrastriatal implantation of human retinal pigment epithelial (hRPE) cells attached to gelatin microcarriers: a potential new cell therapy for Parkinson's disease by Watts, R L, Raiser, C D, Stover, N P, Cornfeldt, M L, Schweikert, A W, Allen, R C, Subramanian, T, Doudet, D, Honey, C R, Bakay, R A E

“…Human retinal pigment epithelial (hRPE) cells are dopaminergic support cells in the neural retina. Stereotaxic intrastriatal implantation of hRPE cells…”
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