Search Results - "Doub, James B"

A pilot study for evaluating the feasibility of using alpha-defensin to support the diagnosis of ventriculitis by Doub, James B.

“…•Conventional ventriculitis diagnostics lack sensitivity and specificity.•Alpha-defensins are a novel diagnostic that can aid in diagnosing…”
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Use of α-Defensins to Help Diagnose Nosocomial Ventriculitis by Doub, James B.

“…Ventriculitis is a severe complication of indwelling neurosurgical devices that is associated with significant morbidity and mortality. The incidence rate of…”
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Bacteriophage Therapy for Clinical Biofilm Infections: Parameters That Influence Treatment Protocols and Current Treatment Approaches by Doub, James B

“…Biofilm infections are extremely difficult to treat, which is secondary to the inability of conventional antibiotics to eradicate biofilms. Consequently,…”
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Concurrent COVID-19 and Pneumocystis jirovecii pneumonia in a severely immunocompromised 25-year-old patient by Bhat, Pavan, Noval, Mandee, Doub, James B., Heil, Emily

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Treatment of Recurrent Severe Cellulitis with a Pill in Pocket Approach by Doub, James B

“…Cellulitis is a common condition that plagues healthcare systems and is associated with significant healthcare costs and resource allocations. With ample…”
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Clinical Ramifications of Bacterial Aggregation in Pleural Fluid by Doub, James B., Putnam, Nicole

“…Background: Bacterial aggregation has been well described to occur in synovial fluid, but it is unknown if bacteria form aggregates in body fluids beyond the…”
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Successful Treatment of a Recalcitrant Staphylococcus epidermidis Prosthetic Knee Infection with Intraoperative Bacteriophage Therapy by Doub, James B, Ng, Vincent Y, Wilson, Eleanor, Corsini, Lorenzo, Chan, Benjamin K

“…Here, we present a case of a 79-year-old female with a recalcitrant prosthetic knee infection that was successfully treated with a single dose of adjuvant…”
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A rare case of extensive Staphylococcus aureus sternoclavicular septic arthritis treated without surgical intervention by Doub, James B.

“…This is a rare case of a 55 year-old immunocompetent female who developed Methicillin sensitive Staphylococcus aureus sternoclavicular septic arthritis. The…”
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Impact of Bacterial Phenotypic Variation with Bacteriophage therapy: A Pilot Study with Prosthetic Joint Infection Isolates by Doub, James B., Urish, Ken, Lee, Martin, Fackler, Joseph

“…•Phage therapy is a promising adjuvant therapeutic in treating prosthetic joint infections•The activity of phages can differ between in vivo S. aureus clinical…”
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Salphage: salvage bacteriophage therapy for a recalcitrant Klebsiella pneumoniae prosthetic shoulder infection - a case report by Doub, James B, Shishido, Akira, Srikumaran, Uma, Haskoor, John, Tran-Nguyen, Phuong, Lee, Myounghee, Würstle, Silvia, Lee, Alina, Kortright, Kaitlyn, Chan, Benjamin K

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Successful Use of Salvage Bacteriophage Therapy for a Recalcitrant MRSA Knee and Hip Prosthetic Joint Infection by Schoeffel, Jonathan, Wang, Elizabeth Wenqian, Gill, Dustin, Frackler, Joseph, Horne, Bri'Anna, Manson, Theodore, Doub, James B

“…Prosthetic joint infections are a serious complication of joint replacement surgery due to the significant morbidity and financial burden that is associated…”
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Salvage Bacteriophage Therapy for a Chronic MRSA Prosthetic Joint Infection by Doub, James B, Ng, Vincent Y, Johnson, Aaron J, Slomka, Magdalena, Fackler, Joseph, Horne, Bri'Anna, Brownstein, Michael J, Henry, Matthew, Malagon, Francisco, Biswas, Biswajit

“…This is a case of a 72 year old male with a chronic methicillin-resistant prosthetic joint infection. After the third intravenous dose of bacteriophage…”
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Retention of Minocycline Susceptibility When Gram-Positive Periprosthetic Joint Infection Isolates Are Non-Susceptible to Doxycycline by Doub, James B., Nandi, Sumon, Putnam, Nicole

“…Background: The treatment of hardware infections often utilizes chronic oral suppression antibiotics to prevent infection recurrence. However, when…”
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Salphage: Salvage bacteriophage therapy for a chronic Enterococcus faecalis prosthetic joint infection by Doub, James B., Chan, Benjamin, Johnson, Aaron J.

“…Chronic prosthetic joint infections are difficult to treat without conducting revision surgery because conventional antibiotics cannot eradicate bacteria that…”
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Salphage: Salvage Bacteriophage Therapy for Recalcitrant MRSA Prosthetic Joint Infection by Doub, James B, Ng, Vincent Y, Lee, Myounghee, Chi, Andrew, Lee, Alina, Würstle, Silvia, Chan, Benjamin

“…Prosthetic joint infections are a devastating complication of joint replacement surgery. Consequently, novel therapeutics are needed to thwart the significant…”
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Feasibility of Using Bacteriophage Therapy to Reduce Morbidity and Mortality Associated with Spinal Epidural Abscesses by Doub, James B, Tran, Jeremy, Smith, Ryan, Pease, Tyler, Koh, Eugene, Ludwig, Stephen, Lee, Alina, Chan, Ben

“…The aim of this study was to determine the feasibility of using bacteriophage therapeutics in spinal epidural abscess (SEA) by reviewing the causes and…”
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Tuberculosis the great masquerader by Wang, Elizabeth Wenqian, Okwesili, Christine N., Doub, James B.

“…With increased use of disease-modifying antirheumatic drugs, screening for latent tuberculosis infection is more important than ever. However, even with…”
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Bacteriophage therapy: are we running before we have learned to walk? by Doub, James B.

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The Location of Biofilms on Chronic Prosthetic Joint Infections and the Ramifications for Clinical Practice by Doub, James B., Parmiter, David, Brantner, Christine A., Moshyedi, Matthew, Hughes, Meghan, Kolevar, Matthew, Johnson, Aaron

“…Revision surgery is paramount to cure chronic prosthetic joint infections because these infections are associated with biofilms on prosthetics that…”
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Rifabutin Use in Staphylococcus Biofilm Infections: A Case Series by Doub, James B., Heil, Emily L., Ntem-Mensah, Afua, Neeley, Renaldo, Ching, Patrick R.

“…This is a case series of 10 patients who had staphylococcal biofilm infections that were treated with adjuvant rifabutin therapy instead of rifampin therapy…”
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