Search Results - "Dou, Yunxiao"
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DDAH-1 maintains endoplasmic reticulum-mitochondria contacts and protects dopaminergic neurons in Parkinson’s disease
Published in Cell death & disease (07-06-2024)“…The loss of dopaminergic neurons in the substantia nigra is a hallmark of pathology in Parkinson’s disease (PD). Dimethylarginine dimethylaminohydrolase-1…”
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Neurotransmitter-stimulated neuron-derived sEVs have opposite effects on amyloid β-induced neuronal damage
Published in Journal of nanobiotechnology (15-10-2021)“…The ratio of excitatory to inhibitory neurotransmitters is essential for maintaining the firing patterns of neural networks, and is strictly regulated within…”
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Repressor Element 1 Silencing Transcription Factor (REST) Governs Microglia-Like BV2 Cell Migration via Progranulin (PGRN)
Published in Neural plasticity (2020)“…Microglia activation contributes to Alzheimer’s disease (AD) etiology, and microglia migration is a fundamental function during microglia activation. The…”
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Aβ-Induced Repressor Element 1-Silencing Transcription Factor (REST) Gene Delivery Suppresses Activation of Microglia-Like BV-2 Cells
Published in Neural plasticity (22-09-2020)“…Compelling evidence from basic molecular biology has demonstrated the crucial role of microglia in the pathogenesis of Alzheimer’s disease (AD). Microglia were…”
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Presequence protease reverses mitochondria‐specific amyloid‐β‐induced mitophagy to protect mitochondria
Published in The FASEB journal (01-05-2023)“…Amyloid‐β (Aβ) peptide is accumulated in the mitochondria and has been shown to play a central role in the development of Alzheimer's disease (AD). It has been…”
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6
Activation of TRPV4 induces intraneuronal tau hyperphosphorylation via cholesterol accumulation
Published in Experimental neurology (01-06-2023)“…Transient receptor potential vanilloid 4 (TRPV4) is a non-selective cation channel, whose aberrant function in neurons has been reported to participate in the…”
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Osteocalcin improves outcome after acute ischemic stroke
Published in Aging (Albany, NY.) (05-01-2020)“…Osteocalcin is related to energy metabolism, memory and the acute stress response, suggesting a relationship between bone and the brain. The need to explore…”
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MiR‐132 down‐regulates high glucose‐induced β‐dystroglycan degradation through Matrix Metalloproteinases‐9 up‐regulation in primary neurons
Published in Journal of cellular and molecular medicine (01-08-2021)“…Cognitive dysfunction is one of the complications of diabetes. Unfortunately, there is no effective methods to block its progression currently. One of the…”
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Neurofilament Light Chain (NF-L) Stimulates Lipid Peroxidation to Neuronal Membrane through Microglia-Derived Ferritin Heavy Chain (FTH) Secretion
Published in Oxidative medicine and cellular longevity (2022)“…A part of the axonal cytoskeleton protein complex, neurofilament light chain (NF-L) has been suggested as a pathological hallmark in various neurological…”
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DDAH1/ADMA Regulates Adiponectin Resistance in Cerebral Ischemia via the ROS/FOXO1/APR1 Pathway
Published in Oxidative medicine and cellular longevity (2022)“…Dimethylarginine dimethylaminohydrolase 1 (DDAH1) protects against cerebral ischemia injury via regulating the level of asymmetric dimethylarginine (ADMA)…”
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11
Neurotransmitter-stimulated neuron-derived sEVs have opposite effects on amyloid [beta]-induced neuronal damage
Published in Journal of nanobiotechnology (15-10-2021)“…The ratio of excitatory to inhibitory neurotransmitters is essential for maintaining the firing patterns of neural networks, and is strictly regulated within…”
Get full text
Journal Article