Search Results - "Dou, Yuhui"
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The human ZC3H3 and RBM26/27 proteins are critical for PAXT-mediated nuclear RNA decay
Published in Nucleic acids research (18-03-2020)“…Abstract Recruitment of the human ribonucleolytic RNA exosome to nuclear polyadenylated (pA+) RNA is facilitated by the Poly(A) Tail eXosome Targeting (PAXT)…”
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Temporal-iCLIP captures co-transcriptional RNA-protein interactions
Published in Nature communications (08-02-2023)“…Dynamic RNA-protein interactions govern the co-transcriptional packaging of RNA polymerase II (RNAPII)-derived transcripts. Yet, our current understanding of…”
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NCBP3 positively impacts mRNA biogenesis
Published in Nucleic acids research (09-10-2020)“…Abstract The nuclear Cap-Binding Complex (CBC), consisting of Nuclear Cap-Binding Protein 1 (NCBP1) and 2 (NCBP2), associates with the nascent 5′cap of RNA…”
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ARS2 instructs early transcription termination-coupled RNA decay by recruiting ZC3H4 to nascent transcripts
Published in Molecular cell (06-07-2023)“…The RNA-binding ARS2 protein is centrally involved in both early RNA polymerase II (RNAPII) transcription termination and transcript decay. Despite its…”
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Affinity proteomic dissection of the human nuclear cap-binding complex interactome
Published in Nucleic acids research (09-10-2020)“…Abstract A 5′,7-methylguanosine cap is a quintessential feature of RNA polymerase II-transcribed RNAs, and a textbook aspect of co-transcriptional RNA…”
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