Search Results - "Doty, Rosalinda A."

MEK Guards Proteome Stability and Inhibits Tumor-Suppressive Amyloidogenesis via HSF1 by Tang, Zijian, Dai, Siyuan, He, Yishu, Doty, Rosalinda A., Shultz, Leonard D., Sampson, Stephen Byers, Dai, Chengkai

“…Signaling through RAS/MAP kinase pathway is central to biology. ERK has long been perceived as the only substrate for MEK. Here, we report that HSF1, the…”
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Loss of TRP53 (p53) accelerates tumorigenesis and changes the tumor spectrum of SJL/J mice by Branca, Jane A., Low, Benjamin E., Saxl, Ruth L., Sargent, Jennifer K., Doty, Rosalinda A., Wiles, Michael V., Dumont, Beth L., Hasham, Muneer G.

“…Known as the guardian of the genome, transformation-related protein 53 (TRP53) is a well -known tumor suppressor. Here, we describe a novel TRP53 deficient…”
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A mouse Col4a4 mutation causing Alport glomerulosclerosis with abnormal collagen α3α4α5(IV) trimers by Korstanje, Ron, Caputo, Christina R, Doty, Rosalinda A, Cook, Susan A, Bronson, Roderick T, Davisson, Muriel T, Miner, Jeffrey H

“…A spontaneous mutation termed bilateral wasting kidneys (bwk) was identified in a colony of NONcNZO recombinant inbred mice. These mice exhibit a rapid…”
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Proliferative Typhlocolitis With Multinucleated Giant Cells: A Nonspecific Enteropathy in Immunodeficient Sentinel Mice by Casey, Kerriann M., Johnson, Amanda L., Hunrath, Melea N., Fraser, Jenelle K., McCowan, Nicole C., Wasson, Katherine, Doty, Rosalinda A., Griffey, Stephen M., Imai, Denise M.

“…Beginning in 2015, athymic nude sentinel mice from conventional, medium-, and high-security facilities presented to the Comparative Pathology Laboratory (CPL)…”
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Histological evaluation of intratumoral myxoma virus treatment in an immunocompetent mouse model of melanoma by Doty, Rosalinda A, Liu, Jia, McFadden, Grant, Roy, Edward J, MacNeill, Amy L

“…Two recombinant myxoma viruses (MYXV expressing a fluorescent protein [MYXV-Tred] and MYXV-Tred encoding murine interleukin-15 [MYXV-IL15]) were evaluated for…”
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An Interleukin‐15 Fusion Protein Enhances the Oncolytic Effects of Myxoma Virus in a Murine Melanoma Model by MacNeill, Amy L, Tosic, Vesna, Doty, Rosalinda A, Liu, Jia, McFadden, Grant, Roy, Edward J

“…Abstract only Myxoma virus (MYXV) has potential as an oncolytic virus, but is not fully effective as a single‐agent therapy. We hypothesized that intratumoral…”
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