Search Results - "Dossou, Akpedje S"
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The Emerging Roles of mTORC1 in Macromanaging Autophagy
Published in Cancers (24-09-2019)“…Autophagy is a process of self-degradation that enables the cell to survive when faced with starvation or stressful conditions. The mechanistic target of…”
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Photophysical Characterization and In Vitro Evaluation of α-Mangostin-Loaded HDL Mimetic Nano-Complex in LN-229 Glioblastoma Spheroid Model
Published in International journal of molecular sciences (05-07-2024)“…Cytotoxic activity has been reported for the xanthone α-mangostin (AMN) against Glioblastoma multiforme (GBM), an aggressive malignant brain cancer with a poor…”
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3
Mannose-Coated Reconstituted Lipoprotein Nanoparticles for the Targeting of Tumor-Associated Macrophages: Optimization, Characterization, and In Vitro Evaluation of Effectiveness
Published in Pharmaceutics (01-06-2023)“…Reconstituted high-density lipoprotein nanoparticles (rHDL NPs) have been utilized as delivery vehicles to a variety of targets, including cancer cells…”
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Pharmacological Modulation of B16‐F10 Murine Melanoma‐Induced TAMs Functional Phenotype via Lipoprotein‐Based Nanoparticles
Published in The FASEB journal (01-05-2022)“…Tumor‐associated macrophages (TAMs) are one of the most abundant immune cells in the tumor microenvironment (TME). Their immunosuppressive phenotype (M2)…”
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5
Mannose-functionalization of reconstituted high-density lipoprotein nanoparticles improves payload delivery and enhances M2-to-M1 phenotype reprogramming of RAW 264.7 macrophages polarized by B16-F10 melanoma cells
Published in Frontiers in Drug Delivery (24-10-2023)“…The targeting and conversion of the immunosuppressive (M2) tumor-associated macrophages (TAMs) to an immunostimulatory (M1) phenotype can induce tumor…”
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Genome Sequences of Five Streptomyces Bacteriophages Forming Cluster BG
Published in Genome announcements (Washington, DC) (13-07-2017)“…Cluster BG of the actinobacteriophage was formed upon discovery of five novel bacteriophages isolated by enrichment from their host, subsp. strain ATCC 10137…”
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Journal Article -
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Optimization and In Vitro Evaluation of Mannose-Decorated Reconstituted High-Density Lipoprotein Nanoparticles for the Targeting of Tumor-Associated Macrophages
Published 01-01-2023“…In several types of cancer, tumor-associated macrophages (TAMs) are educated to an immunosuppressive (M2) phenotype. M2-TAMs contribute to aggressiveness of…”
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Dissertation