Search Results - "Dossin, Fernando M"
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An image-based drug susceptibility assay targeting the placental sequestration of Plasmodium falciparum-infected erythrocytes
Published in PloS one (29-08-2012)“…Placental malaria is a significant cause of all malaria-related deaths globally for which no drugs have been developed to specifically disrupt its…”
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Quantum dots: a new tool for anti-malarial drug assays
Published in Malaria journal (09-05-2011)“…Malaria infects over 300 million people every year and one of the major obstacles for the eradication of the disease is parasite's resistance to current…”
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Automated nuclear analysis of Leishmania major telomeric clusters reveals changes in their organization during the parasite's life cycle
Published in PloS one (11-06-2008)“…Parasite virulence genes are usually associated with telomeres. The clustering of the telomeres, together with their particular spatial distribution in the…”
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Transcription sites are developmentally regulated during the asexual cycle of Plasmodium falciparum
Published in PloS one (07-02-2013)“…Increasing evidence shows that the spatial organization of transcription is an important epigenetic factor in eukaryotic gene regulation. The malaria parasite…”
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Active transcription and ultrastructural changes during Trypanosoma cruzi metacyclogenesis
Published in Anais da Academia Brasileira de Ciências (01-03-2008)“…The differentiation of proliferating epimastigote forms of Trypanosoma cruzi , the protozoan parasite that causes Chagas disease, into the infective and…”
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Cell homeostasis in a Leishmania major mutant overexpressing the spliced leader RNA is maintained by an increased proteolytic activity
Published in The international journal of biochemistry & cell biology (01-10-2010)“…Although several stage-specific genes have been identified in Leishmania, the molecular mechanisms governing developmental gene regulation in this organism are…”
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A high-throughput cell-based assay to screen for drugs affecting PfEMP1 transport to RBC surface
Published in BMC proceedings (10-01-2011)“…Meeting abstracts - A single PDF containing all abstracts in this supplement is available at…”
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