Search Results - "Dossche, Lien"

Desmopressin oral lyophilisate in young children: new insights in pharmacokinetics and pharmacodynamics by Dossche, Lien, Michelet, Robin, De Bruyne, Pauline, Van Herzeele, Charlotte, Gasthuys, Elke, Rittig, Søren, Vermeulen, An, Vande Walle, Johan

“…ObjectiveTo study the pharmacokinetic (PK)/pharmacodynamic (PD) characteristics of desmopressin (dDAVP) oral lyophilisate in children below the age of 8 years…”
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The role of renal circadian biorhythms in lifelong LUTS by Hervé, François, Vande Walle, Johan, Raes, Ann, Haddad, Rebecca, Monaghan, Thomas, Drake, Marcus J., Kamperis, Konstantinos, Dossche, Lien, Zipkin, Jacob, Weiss, Jeffrey, Verbakel, Irina, Bou Kheir, George, Everaert, Karel

“…Introduction This article delves into the intricate relationship between kidney function, diuresis, and lower urinary tract symptoms (LUTS) throughout the…”
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Transition in enuresis patients: Identifying the gaps and opportunities for the future by Karamaria, Sevasti, Mauel, Reiner, Van den Ende, Mauro, Oosterlinck, Ase, Verheye, Alice, De Bruyne, Elke, Degrauewe, Eva, Dhondt, Karlien, Dossche, Lien, Raes, Ann, Renson, Catherine, Samijn, Bieke, Spinoit, Anne‐Françoise, Everaert, Karel, Walle, Johan Vande

“…Background Nocturnal enuresis is generally considered a children's condition, yet it may persist 1%–2% in adolescence and early adulthood. Refractory patients…”
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Paediatric departments need to improve residents’ training in adolescent medicine and health: a position paper of the European Academy of Paediatrics by Michaud, Pierre-André, Schrier, Lenneke, Ross-Russel, Robert, van der Heijden, Laila, Dossche, Lien, Copley, Sian, Alterio, Tommaso, Mazur, Artur, Dembinski, Lukasz, Hadjipanayis, Adamos, del Torso, Stefano, Fonseca, Helena, Ambresin, Anne-Emmanuelle

“…In many European countries, paediatric junior staff has no formal training in adolescent medicine and is ill-equipped to deal with issues and health problems…”
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Claiming desmopressin therapeutic equivalence in children requires pediatric data: a population PKPD analysis by Michelet, Robin, Dossche, Lien, Van Herzeele, Charlotte, Van Bocxlaer, Jan, Vermeulen, An, Vande Walle, Johan

“…Purpose For a new formulation of a drug, only pharmacokinetic bioequivalence with the original formulation has to be demonstrated in healthy, young adults…”
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Ethical considerations of researchers conducting pediatric clinical drug trials: a qualitative survey in two Belgian university children’s hospitals by Van Hoof, Wannes, Meesters, Kevin, Dossche, Lien, Christiaens, Daphné, De Bruyne, Pauline, Vande Walle, Johan

“…There is a general consensus about the underlying theoretical ethical principles that ground the practice of pediatric clinical trials: scientific necessity,…”
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The choice between deceased‐ vs living‐donor renal transplantation in children: Analysis of data from a Belgian tertiary center by Van Cauwenberghe, Katty, Raes, Ann, Pauwels, Lut, Dehoorne, Jo, Colenbie, Luc, Dequidt, Clement, Dossche, Lien, Vande Walle, Johan, Prytuła, Agnieszka

“…Pediatric renal transplantation with a living donor (LD) has superior outcome, but there is a paucity of studies analyzing the reasons for not undertaking…”
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Could Evening Dietary Protein Intake Play a Role in Nocturnal Polyuria? by Alwis, Upeksha S., Delanghe, Joris, Dossche, Lien, Walle, Johan Vande, Van Camp, John, Monaghan, Thomas F., Roggeman, Saskia, Everaert, Karel

“…Urea is the most abundant and the largest contributing factor for urine osmolality. Urinary urea excretion is highly interrelated with dietary protein intake…”
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Impact of New vs. Old International Children's Continence Society Standardization on the Classification of Treatment Naïve Enuresis Children at Screening: The Value of Voiding Diaries and Questionnaires by Karamaria, Sevasti, Ranguelov, Nadejda, Hansen, Pernille, De Boe, Veerle, Verleyen, Pieter, Segers, Nathalie, Walle, Johan Vande, Dossche, Lien, Bael, An

“…Expert consensus papers recommend differentiating enuresis using questionnaires and voiding diaries into non- (NMNE) and monosymptomatic enuresis (MNE) is…”
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Effect of desmopressin on water and solute circadian rhythms in treatment-naïve children with monosymptomatic enuresis and nocturnal polyuria by Karamaria, Sevasti, Dossche, Lien, Dhondt, Karlien, Everaert, Karel, Van Herzeele, Charlotte, Walle, Johan Vande, Raes, Ann

“…Enuresis has a complex pathophysiology involving nocturnal polyuria, reduced bladder capacity at nighttime, and impaired arousability. Desmopressin has long…”
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Circadian rhythm of water and solute excretion in nocturnal enuresis by Karamaria, Sevasti, Dossche, Lien, Delens, Vincent, Degraeuwe, Eva, Raes, Ann, Mauel, Reiner, Vande Walle, Caroline, Everaert, Karel, Vande Walle, Johan

“…Background Nocturnal polyuria (NP) due to a suppressed vasopressin circadian rhythm is a well-documented pathogenetic mechanism in enuresis, mainly studied in…”
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Real-world evidence of lisinopril in pediatric hypertension and nephroprotective management: a 10-year cohort study by Degraeuwe, Eva, Gasthuys, Elke, Snauwaert, Evelien, Dossche, Lien, Prytula, Agnieszka, Dehoorne, Joke, Vermeulen, An, Walle, Johan Vande, Raes, Ann

“…Over the last 20 years, pediatric hypertension (pHTN) prevalence in Western society has risen from 3.5 to 9% due to childhood overweight, obesity, and…”
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Reply by Authors by Jørgensen, Cecilie Siggaard, Dossche, Lien, Zhai, Rongqun, Maternik, Michal, Kamperis, Konstantinos, Breinbjerg, Anders S, Karamaria, Sevasti, Thorsteinsson, Kristina, Borg, Britt, Wang, Yihe, Li, Shuai, Raes, Ann, Wei, Lu, Żurowska, Aleksandra, Hagstrøm, Søren, Walle, Johan Vande, Guo, Wen Jian, Rittig, Søren

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Reply by Authors by Jørgensen, Cecilie Siggaard, Dossche, Lien, Zhai, Rongqun, Maternik, Michal, Kamperis, Konstantinos, Breinbjerg, Anders S., Karamaria, Sevasti, Thorsteinsson, Kristina, Borg, Britt, Wang, Yihe, Li, Shuai, Raes, Ann, Wei, Lu, Żurowska, Aleksandra, Hagstrøm, Søren, Walle, Johan Vande, Guo, Wen Jian, Rittig, Søren

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The Influence of Salt Sensitivity Phenotype on Sodium Excretion and Diuresis: A Chrononutrition Pilot Study by Alwis, Upeksha Sewwandi, Verbakel, Irina, Pauwaert, Kim, Delanghe, Joris, Dossche, Lien, Van Camp, John, Roggeman, Saskia, Everaert, Karel

“…Background. Chrononutrition studies on interaction of diet/nutrients on endogenous circadian clocks and meal timing on metabolic homeostasis may be of…”
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The efficacy of standard urotherapy in the treatment of nocturnal enuresis in children: A systematic review by Jørgensen, Cecilie Siggaard, Kamperis, Konstantinos, Walle, Johan Vande, Rittig, Søren, Raes, Ann, Dossche, Lien

“…Standard urotherapy in children with nocturnal enuresis (NE) is first-line treatment according to the current International Children's Continence Society…”
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Development of a Novel Prediction Tool for Response to First-Line Treatments of Monosymptomatic Nocturnal Enuresis: A Randomized, Controlled, International, Multicenter Study (DRYCHILD) by Jørgensen, Cecilie Siggaard, Dossche, Lien, Zhai, Rongqun, Maternik, Michal, Kamperis, Konstantinos, Breinbjerg, Anders S, Karamaria, Sevasti, Thorsteinsson, Kristina, Borg, Britt, Wang, Yihe, Li, Shuai, Raes, Ann, Wei, Lu, Żurowska, Aleksandra, Hagstrøm, Søren, Walle, Johan Vande, Guo, Wen Jian, Rittig, Søren

“…Nocturnal urine volume and bladder reservoir function are key pathogenic factors behind monosymptomatic nocturnal enuresis (MNE). We investigated the…”
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Discontinuing absorbent pants in children with bedwetting: a randomized controlled trial by Breinbjerg, Anders, Kamperis, Konstantinos, Thorsteinsson, Kristina, Jørgensen, Cecilie Siggaard, Dossche, Lien, Rayner, Juliette, Zhang, Jin, Rodrigues, Debora Garcia, Borch, Luise, Hagstrøm, Søren, Tekgül, Serdar, Walle, Johan Vande, Rittig, Søren

“…The objective of this study is to examine the effect of discontinuing wearing protective garments (absorbent pyjama pants — APP) in children with severe…”
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Pediatric Pharmacology of Desmopressin in Children with Enuresis: A Comprehensive Review by Gasthuys, Elke, Dossche, Lien, Michelet, Robin, Nørgaard, Jens Peter, Devreese, Mathias, Croubels, Siska, Vermeulen, An, Van Bocxlaer, Jan, Walle, Johan Vande

“…Desmopressin is a synthetic analogue of the natural antidiuretic hormone arginine vasopressin. Over the years, it has been clinically used to manage nocturnal…”
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An Integrated Paediatric Population PK/PD Analysis of dDAVP: How do PK Differences Translate to Clinical Outcomes? by Michelet, Robin, Dossche, Lien, Van Herzeele, Charlotte, De Bruyne, Pauline, Gasthuys, Elke, Van Bocxlaer, Jan, Vande Walle, Johan, Vermeulen, An

“…Introduction The bioequivalence of two formulations of desmopressin (dDAVP), a vasopressin analogue prescribed for nocturnal enuresis treatment in children,…”
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