Search Results - "Dossa, Robson G"

Development of T-cell immunotherapy for hematopoietic stem cell transplantation recipients at risk of leukemia relapse by Dossa, Robson G., Cunningham, Tanya, Sommermeyer, Daniel, Medina-Rodriguez, Indira, Biernacki, Melinda A., Foster, Kimberly, Bleakley, Marie

“…Leukemia relapse remains the major cause of allogeneic hematopoietic stem cell transplantation (HCT) failure, and the prognosis for patients with post-HCT…”
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CBFB-MYH11 fusion neoantigen enables T cell recognition and killing of acute myeloid leukemia by Biernacki, Melinda A, Foster, Kimberly A, Woodward, Kyle B, Coon, Michael E, Cummings, Carrie, Cunningham, Tanya M, Dossa, Robson G, Brault, Michelle, Stokke, Jamie, Olsen, Tayla M, Gardner, Kelda, Estey, Elihu, Meshinchi, Soheil, Rongvaux, Anthony, Bleakley, Marie

“…Proteins created from recurrent fusion genes like CBFB-MYH11 are prevalent in acute myeloid leukemia (AML), often necessary for leukemogenesis, persistent…”
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HA-1–targeted T-cell receptor T-cell therapy for recurrent leukemia after hematopoietic stem cell transplantation by Krakow, Elizabeth F., Brault, Michelle, Summers, Corinne, Cunningham, Tanya M., Biernacki, Melinda A., Black, R. Graeme, Woodward, Kyle B., Vartanian, Nicole, Kanaan, Sami B., Yeh, Albert C., Dossa, Robson G., Bar, Merav, Cassaday, Ryan D., Dahlberg, Ann, Till, Brian G., Denker, Andrew E., Yeung, Cecilia C. S., Gooley, Ted A., Maloney, David G., Riddell, Stanley R., Greenberg, Philip D., Chapuis, Aude G., Newell, Evan W., Furlan, Scott N., Bleakley, Marie

“…•This trial used a class I–restricted TCR and a CD8 coreceptor to enable antigen–specific CD8+ and CD4+ T-cell function.•Primary end points of feasibility and…”
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The equine CD1 gene family is the largest and most diverse yet identified by Dossa, Robson G., Alperin, Debra C., Hines, Melissa T., Hines, Stephen A.

“…The CD1 family is a group of non-polymorphic MHC class I-like molecules that present lipid-based antigens to T cells. Previous work in our laboratory…”
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In contrast to other species, α-Galactosylceramide (α-GalCer) is not an immunostimulatory NKT cell agonist in horses by Dossa, Robson G., Alperin, Debra C., Garzon, Diana, Mealey, Robert H., Brown, Wendy C., Jervis, Peter J., Besra, Gurdyal S., Cox, Liam R., Hines, Stephen A.

“…•The equine CD1d has a suitable pocket for α-GalCer ligation.•α-GalCer failed to stimulate equine NKT cells in vitro or in vivo.•α-GalCer loaded tetramers did…”
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