Search Results - "Dosescu, J"

Cathepsin B and tumor proteolysis: contribution of the tumor microenvironment by Sloane, Bonnie F., Yan, Shiqing, Podgorski, Izabela, Linebaugh, Bruce E., Cher, Michael L., Mai, Jianxin, Cavallo-Medved, Dora, Sameni, Mansoureh, Dosescu, Julie, Moin, Kamiar

“…Tumor–stromal interactions induce expression of matrix metalloproteinases and serine proteases and, as shown recently, the cysteine protease cathepsin B. We…”
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Imaging proteolysis by living human glioma cells by Sameni, M, Dosescu, J, Sloane, B F

“…Degradation of basement membrane is an essential step for tumor invasion. In order to study degradation in real time as well as localize the site of…”
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Clonal growth inhibition as a bioassay for thymosin alpha1: inactivation of Talpha1 by trifluroacetic acid by Bianco-Batlles, D, Naylor, C W, Moshier, J A, Dosescu, J, Naylor, P H

“…Thymosin alpha1 (Talpha1) is an immune response modifying peptide isolated from thymus tissue. The synthetic peptide has been evaluated in clinical trials as…”
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Caveolin-1 mediates the expression and localization of cathepsin B, pro-urokinase plasminogen activator and their cell-surface receptors in human colorectal carcinoma cells by Cavallo-Medved, Dora, Mai, Jianxin, Dosescu, Julie, Sameni, Mansoureh, Sloane, Bonnie F

“…Cathepsin B and pro-urokinase plasminogen activator (pro-uPA) localize to the caveolae of HCT 116 human colorectal carcinoma cells, an association mediated by…”
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Isolation and expression of a human ornithine decarboxylase gene by MOSHIER, J. A, GILBERT, J. D, SKUNCA, M, DOSESCU, J, ALMODOVAR, K. M, LUK, G. D

“…We have isolated a human ornithine decarboxylase (ODC) gene from a leukocyte genomic DNA library in order to examine the mechanisms involved in the regulation…”
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Ornithine decarboxylase and tyrosine kinase activity in juvenile polyps of childhood by ELITSUR, Y, KOH, S. J. G, MOSHIER, J. A, DODESCU, J, TUREAUD, J, MAJUMDAR, A. P. N

“…Juvenile polyps (JP) are the most common colonic tumor in children. Although considered benign, malignant transformation has been reported in JP. Ornithine…”
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Neuropeptide Y (NPY) enhances proliferation of human colonic lamina propria lymphocytes by Elitsur, Y, Luk, G D, Colberg, M, Gesell, M S, Dosescu, J, Moshier, J A

“…Neuropeptide Y (NPY) is one member of a family of peptides with a wide range of physiological effects on the CNS, cardiovascular, and respiratory systems. NPY…”
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Human vaginal mucosal immune system: characterization and function by Elitsur, Y, Jackman, S, Neace, C, Keerthy, S, Liu, X, Dosescu, J, Moshier, J A

“…The mucosal immune system has been recognized as the first line of defense against foreign antigens. The limited information available on the mucosal immunity…”
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Mutant K-ras Regulates Cathepsin B Localization on the Surface of Human Colorectal Carcinoma Cells by Cavallo-Medved, Dora, Dosescu, Julie, Linebaugh, Bruce E., Sameni, Mansoureh, Rudy, Debbie, Sloane, Bonnie F.

“…Cathepsin B protein and activity are known to localize to the basal plasma membrane of colon carcinoma cells following the appearance of K-ras mutations. Using…”
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Interaction of Human Breast Fibroblasts with Collagen I Increases Secretion of Procathepsin B by Koblinski, Jennifer E, Dosescu, Julie, Sameni, Mansoureh, Moin, Kamiar, Clark, Katherine, Sloane, Bonnie F

“…Interactions of stromal and tumor cells with the extracellular matrix may regulate expression of proteases including the lysosomal proteases cathepsins B and…”
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Transformation of NIH/3T3 cells by ornithine decarboxylase overexpression by MOSHIER, J. A, DOSESCU, J, SKUNCA, M, LUK, G. D

“…Ornithine decarboxylase (ODC) plays a rate-limiting role in polyamine biosynthesis and is intimately associated with cell proliferation and function. Although…”
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TGFalpha is required for full expression of the transformed growth phenotype of NIH 3T3 cells overexpressing ornithine decarboxylase by Geng, H, Naylor, P H, Dosescu, J, Skunca, M, Majumdar, A P, Moshier, J A

“…Ornithine decarboxylase (ODC) overexpressed from a heterologous promoter drives the tumorigenic transformation of NIH 3T3 cells and provides a model to…”
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Tryosine kinase and ornithine decarboxylase activation in children with Helicobactor pylori gastritis by Elitsur, Y, Majumdar, A P, Tureaud, J, Dosescu, J, Neace, C, Velusamy, L, Moshier, J A

“…H. pylori infection has been considered a risk factor for the development of gastric malignancy. Ornithine decarboxylase and tyrosine kinases activities are…”
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Regulation of Ornithine Decarboxylase Gene Expression by the Wilms' Tumor Suppressor WT1 by Moshier, Jeffrey A., Skunca, Magdalena, Wu, Wei, Boppana, Sita M., Rauscher, Frank J., Dosescu, Julie

“…The importance of ornithine decarboxylase (ODC) to cell proliferation is underscored by the complex array of cell-specific mechanisms invoked to regulate its…”
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TGF  is required for full expression of the transformed growth phenotype of NIH 3T3 cells overexpressing ornithine decarboxylase by Geng, H., Naylor, P. H., Dosescu, J., Skunca, M., Majumdar, A. P.N., Moshier, J. A.

“…Ornithine decarboxylase (ODC) overexpressed from a heterologous promoter drives the tumorigenic transformation of NIH 3T3 cells and provides a model to…”
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Ornithine decarboxylase transformation of NIH/3T3 cells is mediated by altered epidermal growth factor receptor activity by MOSHIER, J. A, MALECKA-PANAS, E, GENG, H, DOSESCU, J, TUREAUD, J, SKUNCA, M, MAJUMDAR, A. P. N

“…Ornithine decarboxylase (ODC) has been shown to be oncogenic in transfected NIH/3T3 cells overexpressing the enzyme from a heterologous promoter. These cells,…”
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Tyrosine kinase and ornithine decarboxylase activation in children with helicobacter pylori gastritis by Elitsur, Yoram, Majumdar, Adip P.N., Tureaud, John, Dosescu, Julie, Neace, Cheryl, Velusamy, Latha, Moshier, Jeffrey A.

“…H. pylori infection has been considered a risk factor for the development of gastric malignancy. Ornithine decarboxylase and tyrosine kinases activities are…”
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TGFα is required for full expression of the transformed growth phenotype of NIH 3T3 cells overexpressing ornithine decarboxylase by Geng, Hairong, Naylor, Paul H., Dosescu, Julie, Skunca, Magdalena, Majumdar, Adhip P.N., Moshier, Jeffrey A.

“…Ornithine decarboxylase (ODC) overexpressed from a heterologous promoter drives the tumorigenic transformation of NIH 3T3 cells and provides a model to…”
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CYTOKINE-MEDIATED APOPTOSIS AND INHIBITION OF VIRUS PRODUCTION AND ANCHORAGE INDEPENDENT GROWTH OF VIRAL TRANSFECTED HEPATOBLASTOMA CELLS by Yared, George, Hussain, Khozema B., Nathani, Muhammed G., Moshier, Jeffrey A., Dosescu, Julie, Mutchnick, Milton G., Naylor, Paul H.

“…Cytokine-mediated apoptotic destruction of viral-infected cells, downregulation of virus production and inhibition of anchorage dependent (clonal) cell growth…”
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Thymosin-α1, but not interferon-α, specifically inhibits anchorage-independent growth of hepatitis B viral transfected HepG2 cells by MOSHIER, J. A, MUTCHNICK, M. G, DOSESCU, J, HOLTZ, T. K, AKKARY, S, MAHAKALA, K, MERLINE, J. R, NAYLOR, P. H

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