Search Results - "Doser, Rachel L"
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Activity-dependent mitochondrial ROS signaling regulates recruitment of glutamate receptors to synapses
Published in eLife (14-03-2024)“…Our understanding of mitochondrial signaling in the nervous system has been limited by the technical challenge of analyzing mitochondrial function in vivo. In…”
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Regulation of neuronal excitability by reactive oxygen species and calcium signaling: Insights into brain aging
Published in Current research in neurobiology (2021)“…Altered cognition and inefficient learning and memory are hallmarks of brain aging resulting from many small changes in the structure and function of neurons…”
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Surface acoustic wave microfluidics for repetitive and reversible temporary immobilization of C. elegans
Published in Lab on a chip (06-12-2022)“…is an important genetic model for neuroscience studies, used for analyses of how genes control connectivity, neuronal function, and behavior. To date, however,…”
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Reactive Oxygen Species Modulate Activity-Dependent AMPA Receptor Transport in C. elegans
Published in The Journal of neuroscience (23-09-2020)“…The AMPA subtype of synaptic glutamate receptors (AMPARs) plays an essential role in cognition. Their function, numbers, and change at synapses during synaptic…”
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A Necessary Role for PKC-2 and TPA-1 in Olfactory Memory and Synaptic AMPAR Trafficking in Caenorhabditis elegans
Published in The Journal of neuroscience (06-03-2024)“…Protein kinase C (PKC) functions are essential for synaptic plasticity, learning, and memory. However, the roles of specific members of the PKC family in…”
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MAPK signaling and a mobile scaffold complex regulate AMPA receptor transport to modulate synaptic strength
Published in Cell reports (Cambridge) (29-03-2022)“…Synaptic plasticity depends on rapid experience-dependent changes in the number of neurotransmitter receptors. Previously, we demonstrated that motor-mediated…”
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Spontaneous motor-behavior abnormalities in two Drosophila models of neurodevelopmental disorders
Published in Journal of neurogenetics (02-01-2021)“…Mutations in hundreds of genes cause neurodevelopmental disorders with abnormal motor behavior alongside cognitive deficits. Boys with fragile X syndrome…”
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Decreased Reactive Oxygen Species Signaling Alters Glutamate Receptor Transport to Synapses in C. elegans AVA Neurons
Published in microPublication biology (2022)“…Reactive oxygen species (ROS) are chemically reactive molecules normally produced during cellular respiration. High ROS levels negatively impact forms of…”
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