Search Results - "Dos Reis, Diego Carlos"
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CFTR High Expresser Cells in cystic fibrosis and intestinal diseases
Published in Heliyon (01-03-2023)“…Cystic Fibrosis Transmembrane Conductance Regulator (CFTR), the Cl−/HCO3− channel implicated in Cystic Fibrosis, is critical to the pathophysiology of many…”
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Marine Seagrass Extract of Thalassia testudinum Suppresses Colorectal Tumor Growth, Motility and Angiogenesis by Autophagic Stress and Immunogenic Cell Death Pathways
Published in Marine drugs (22-01-2021)“…Marine plants have become an inexhaustible reservoir of new phytopharmaceuticals for cancer treatment. We demonstrate in vitro/in vivo antitumor efficacy of a…”
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Omega-3 fatty acid supplementation attenuates intestinal mucositis and tumor growth in a murine model of breast cancer
Published in Journal of functional foods (01-04-2024)“…[Display omitted] •Omega-3 supplementation ameliorates intestinal mucositis.•The RNA expression of tight juctions were enhance by ômega-3…”
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Pharmacological blockade of protease-Activated Receptor 2 improves airway remodeling and lung inflammation in experimental allergic asthma
Published in Brazilian Journal of Pharmaceutical Sciences (01-01-2022)“…Abstract Protease-activated receptors (PARs) are metabotropic G-protein-coupled receptors that are activated via proteolytic cleavage of a specific sequence of…”
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Protective effects of milk fermented by Lactobacillus plantarum B7 from Brazilian artisanal cheese on a Salmonella enterica serovar Typhimurium infection in BALB/c mice
Published in Journal of functional foods (01-06-2017)“…•New probiotic Lactobacillus plantarum strain from Brazilian’s Minas artisanal cheese.•Protective effect of L. plantarum B7 sample was observed in murine…”
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Localization and function of humanized F508del-CFTR in mouse intestine following activation of serum glucocorticoid kinase 1 and Trikafta
Published in European journal of pharmacology (05-09-2024)“…The CFTR modulator Trikafta has markedly improved lung disease for Cystic Fibrosis (CF) patients carrying the common delta F508 (F508del-CFTR) CFTR mutation…”
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Evaluation of the improvement of quality of life with Azithromycin in the treatment of eosinophilic nasal polyposis
Published in Brazilian journal of otorhinolaryngology (01-03-2016)“…The Sino-Nasal Outcome Test 22 (SNOT-22) is an important tool in assessing the quality of life (QoL) of patients with chronic rhinosinusitis with a validated…”
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Thalidomide promotes leukocytosis in mice inoculated with 4T1 mammary carcinoma
Published in Jornal brasileiro de patologia e medicina laboratorial (01-02-2014)“…The aim of this study was to evaluate the therapy effect of thalidomide in the 4T1 murine mammary carcinoma. 4T1 cell suspension was injected into the…”
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Prophylactic and therapeutic supplementation using fructo-oligosaccharide improves the intestinal homeostasis after mucositis induced by 5- fluorouracil
Published in Biomedicine & pharmacotherapy (01-01-2021)“…[Display omitted] •Fructo-oligosaccharides (FOS) retained intestinal permeability and tight junctions.•FOS improved short-chain fatty acid production in…”
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Antiproliferative, Antiangiogenic, and Antimetastatic Therapy Response by Mangiferin in a Syngeneic Immunocompetent Colorectal Cancer Mouse Model Involves Changes in Mitochondrial Energy Metabolism
Published in Frontiers in pharmacology (03-12-2021)“…In spite of the current advances and achievements in cancer treatments, colorectal cancer (CRC) persists as one of the most prevalent and deadly tumor types in…”
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Versican and Tumor-Associated Macrophages Promotes Tumor Progression and Metastasis in Canine and Murine Models of Breast Carcinoma
Published in Frontiers in oncology (03-07-2019)“…Versican and tumor-associated macrophages (TAMs) are involved in growth and metastases in several cancers. Here, we investigated the potential role of…”
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Milk Fermented by Lactobacillus paracasei NCC 2461 (ST11) Modulates the Immune Response and Microbiota to Exert its Protective Effects Against Salmonella typhimurium Infection in Mice
Published in Probiotics and antimicrobial proteins (01-12-2020)“…Probiotics form a promising strategy to maintain intestinal health. Milks fermented with probiotic strains, such as the Lactobacillus paracasei ST11, are…”
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Tissue-selective inflammation in the oral cavity of the rat
Published in Inflammopharmacology (01-08-2016)“…In the current study, carrageenan (CG; 100–1000 μg/site) was injected intraorally in the cheeks of Holtzman or Wistar rats to evaluate the consequences of…”
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Azithromycin for the Treatment of Eosinophilic Nasal Polyposis: Clinical and Histologic Analysis
Published in Allergy & rhinology (Providence, R.I.) (01-01-2016)“…Introduction Macrolides used as immunomodulators are a promising tool for chronic inflammatory airway diseases. Eosinophilic nasal polyposis (ENP) is still…”
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Diet-induced obesity leads to alterations in behavior and gut microbiota composition in mice
Published in The Journal of nutritional biochemistry (01-06-2021)“…The high prevalence of obesity and associated metabolic disorders are one of the major public health problems worldwide. Among the main causal factors of…”
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1039 ROLE OF CFTR HIGH EXPRESSOR CELLS (CHES) IN CYSTIC FIBROSIS INTESTINAL DISEASE
Published in Gastroenterology (New York, N.Y. 1943) (01-05-2023)Get full text
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Serum and Glucocorticoid‐Inducible Kinase 1 (SGK1): An Important Contributor to Diarrhea and Malabsorption in Microvillus Inclusion Disease (MVID)
Published in The FASEB journal (01-05-2022)“…Microvillus Inclusion Disease (MVID) is a lethal congenital diarrheal disease resulting from loss of function mutations in the actin motor myosin VB (MYO5B)…”
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Clinical significance and prognostic role of tumor-associated macrophages infiltration according to histologic location in canine mammary carcinomas
Published in Research in veterinary science (01-03-2021)“…Tumor-associated macrophages (TAMs) have been involved in growth and metastases of human and canine mammary tumors. However, the prognostic importance of TAM…”
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