Search Results - "Dorsky, Richard I"

Development of the hypothalamus: conservation, modification and innovation by Xie, Yuanyuan, Dorsky, Richard I

“…The hypothalamus, which regulates fundamental aspects of physiological homeostasis and behavior, is a brain region that exhibits highly conserved anatomy…”
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Radial glial progenitors repair the zebrafish spinal cord following transection by Briona, Lisa K., Dorsky, Richard I.

“…In mammals, spinal cord injury results in permanent sensory–motor loss due in part to a failure in reinitiating local neurogenesis. However, zebrafish show…”
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Wnt/β-Catenin Signaling Defines Organizing Centers that Orchestrate Growth and Differentiation of the Regenerating Zebrafish Caudal Fin by Wehner, Daniel, Cizelsky, Wiebke, Vasudevaro, Mohankrishna Dalvoy, Özhan, Günes, Haase, Christa, Kagermeier-Schenk, Birgit, Röder, Alexander, Dorsky, Richard I., Moro, Enrico, Argenton, Francesco, Kühl, Michael, Weidinger, Gilbert

“…Zebrafish regenerate their fins via the formation of a population of progenitor cells, the blastema. Wnt/β-catenin signaling is essential for blastemal cell…”
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Unique advantages of zebrafish larvae as a model for spinal cord regeneration by Alper, Samuel R, Dorsky, Richard I

“…The regenerative capacity of the spinal cord in mammals ends at birth. In contrast, teleost fish and amphibians retain this capacity throughout life, leading…”
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Motor Behavior Mediated by Continuously Generated Dopaminergic Neurons in the Zebrafish Hypothalamus Recovers after Cell Ablation by McPherson, Adam D., Barrios, Joshua P., Luks-Morgan, Sasha J., Manfredi, John P., Bonkowsky, Joshua L., Douglass, Adam D., Dorsky, Richard I.

“…Postembryonic neurogenesis has been observed in several regions of the vertebrate brain, including the dentate gyrus and rostral migratory stream in mammals,…”
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Identification of Wnt Genes Expressed in Neural Progenitor Zones during Zebrafish Brain Development by Duncan, Robert N, Panahi, Samin, Piotrowski, Tatjana, Dorsky, Richard I

“…Wnt signaling regulates multiple aspects of vertebrate central nervous system (CNS) development, including neurogenesis. However, vertebrate genomes can…”
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Bsx Is Essential for Differentiation of Multiple Neuromodulatory Cell Populations in the Secondary Prosencephalon by Schredelseker, Theresa, Veit, Florian, Dorsky, Richard I., Driever, Wolfgang

“…The hypothalamus is characterized by great neuronal diversity, with many neuropeptides and other neuromodulators being expressed within its multiple anatomical…”
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A toolbox to study epidermal cell types in zebrafish by Eisenhoffer, George T, Slattum, Gloria, Ruiz, Oscar E, Otsuna, Hideo, Bryan, Chase D, Lopez, Justin, Wagner, Daniel S, Bonkowsky, Joshua L, Chien, Chi-Bin, Dorsky, Richard I, Rosenblatt, Jody

“…Epithelia provide a crucial protective barrier for our organs and are also the sites where the majority of carcinomas form. Most studies on epithelia and…”
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Wnt Signaling Regulates Postembryonic Hypothalamic Progenitor Differentiation by Wang, Xu, Kopinke, Daniel, Lin, Junji, McPherson, Adam D., Duncan, Robert N., Otsuna, Hideo, Moro, Enrico, Hoshijima, Kazuyuki, Grunwald, David J., Argenton, Francesco, Chien, Chi-Bin, Murtaugh, L. Charles, Dorsky, Richard I.

“…Previous studies have raised the possibility that Wnt signaling may regulate both neural progenitor maintenance and neuronal differentiation within a single…”
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Lef1-dependent hypothalamic neurogenesis inhibits anxiety by Xie, Yuanyuan, Kaufmann, Dan, Moulton, Matthew J, Panahi, Samin, Gaynes, John A, Watters, Harrison N, Zhou, Dingxi, Xue, Hai-Hui, Fung, Camille M, Levine, Edward M, Letsou, Anthea, Brennan, K C, Dorsky, Richard I

“…While innate behaviors are conserved throughout the animal kingdom, it is unknown whether common signaling pathways regulate the development of neuronal…”
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Canonical Wnt signaling through Lef1 is required for hypothalamic neurogenesis by Lee, Ji Eun, Wu, Shan-Fu, Goering, Lisa M, Dorsky, Richard I

“…Although the functional importance of the hypothalamus has been demonstrated throughout vertebrates, the mechanisms controlling neurogenesis in this forebrain…”
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Reiterated Wnt signaling during zebrafish neural crest development by Lewis, Jessica L, Bonner, Jennifer, Modrell, Melinda, Ragland, Jared W, Moon, Randall T, Dorsky, Richard I, Raible, David W

“…While Wnt/β-catenin signaling is known to be involved in the development of neural crest cells in zebrafish, it is unclear which Wnts are involved, and when…”
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High‐resolution analysis of central nervous system expression patterns in zebrafish Gal4 enhancer‐trap lines by Otsuna, Hideo, Hutcheson, David A., Duncan, Robert N., McPherson, Adam D., Scoresby, Aaron N., Gaynes, Brooke F., Tong, Zongzong, Fujimoto, Esther, Kwan, Kristen M., Chien, Chi‐Bin, Dorsky, Richard I.

“…Background: The application of the Gal4/UAS system to enhancer and gene trapping screens in zebrafish has greatly increased the ability to label and manipulate…”
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The zebrafish zic2a-zic5 gene pair acts downstream of canonical Wnt signaling to control cell proliferation in the developing tectum by Nyholm, Molly K, Wu, Shan-Fu, Dorsky, Richard I, Grinblat, Yevgenya

“…Wnt growth factors acting through the canonical intracellular signaling cascade play fundamental roles during vertebrate brain development. In particular,…”
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Dopaminergic neuronal cluster size is determined during early forebrain patterning by Russek-Blum, Niva, Gutnick, Amos, Nabel-Rosen, Helit, Blechman, Janna, Staudt, Nicole, Dorsky, Richard I, Houart, Corinne, Levkowitz, Gil

“…We have explored the effects of robust neural plate patterning signals, such as canonical Wnt, on the differentiation and configuration of neuronal subtypes in…”
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Hh and Wnt signaling regulate formation of olig2 + neurons in the zebrafish cerebellum by McFarland, Karen A., Topczewska, Jolanta M., Weidinger, Gilbert, Dorsky, Richard I., Appel, Bruce

“…The cerebellum, which forms from anterior hindbrain, coordinates motor movements and balance. Sensory input from the periphery is relayed and modulated by…”
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Canonical Wnt signaling is required for the maintenance of dorsal retinal identity by Veien, Eric S, Rosenthal, Judith S, Kruse-Bend, Renee C, Chien, Chi-Bin, Dorsky, Richard I

“…Accurate retinotectal axon pathfinding depends upon the correct establishment of dorsal-ventral retinal polarity. We show that dorsal retinal gene expression…”
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Two tcf3 genes cooperate to pattern the zebrafish brain by Dorsky, Richard I, Itoh, Motoyuki, Moon, Randall T, Chitnis, Ajay

“…Caudalizing factors operate in the context of Wnt/β-catenin signaling to induce gene expression in discrete compartments along the rostral-caudal axis of the…”
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Progenitor expansion in apc mutants is mediated by Jak/Stat signaling by Lin, Junji, Wang, Xu, Dorsky, Richard I

“…Mutations in APC, a negative regulator of the Wnt/ß-catenin pathway, can cause cancer as well as profound developmental defects. In both cases, affected cells…”
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Tcf3 inhibits spinal cord neurogenesis by regulating sox4a expression by Gribble, Suzanna L, Kim, Hyung-Seok, Bonner, Jennifer, Wang, Xu, Dorsky, Richard I

“…The Lef/Tcf factor Tcf3 is expressed throughout the developing vertebrate central nervous system (CNS), but its function and transcriptional targets are…”
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