Search Results - "Dorsett, Y"
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Dendritic cells induce peripheral T cell unresponsiveness under steady state conditions in vivo
Published in The Journal of experimental medicine (17-09-2001)“…Dendritic cells (DCs) have the capacity to initiate immune responses, but it has been postulated that they may also be involved in inducing peripheral…”
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siRNAs: applications in functional genomics and potential as therapeutics
Published in Nature reviews. Drug discovery (01-04-2004)“…Molecules that can specifically silence gene expression are powerful research tools. Much effort has been put into the development of such molecules and has…”
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Human Argonaute2 Mediates RNA Cleavage Targeted by miRNAs and siRNAs
Published in Molecular cell (23-07-2004)“…Argonaute proteins associate with small RNAs that guide mRNA degradation, translational repression, or a combination of both. The human Argonaute family has…”
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AID Is Required for the Chromosomal Breaks in c-myc that Lead to c-myc/IgH Translocations
Published in Cell (12-12-2008)“…Chromosomal translocation requires formation of paired double-strand DNA breaks (DSBs) on heterologous chromosomes. One of the most well characterized…”
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Sequence-specific inhibition of microRNA- and siRNA-induced RNA silencing
Published in RNA (Cambridge) (01-03-2004)“…A large number of miRNAs have recently been discovered in plants and animals. Development of reverse genetic approaches that act to inhibit microRNA function…”
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