Search Results - "Dorsett, Dale"

Roles of the sister chromatid cohesion apparatus in gene expression, development, and human syndromes by Dorsett, Dale

“…The sister chromatid cohesion apparatus mediates physical pairing of duplicated chromosomes. This pairing is essential for appropriate distribution of…”
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The Ancient and Evolving Roles of Cohesin in Gene Expression and DNA Repair by Dorsett, Dale, Ström, Lena

“…The cohesin complex, named for its key role in sister chromatid cohesion, also plays critical roles in gene regulation and DNA repair. It performs all three…”
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Brca2, Pds5 and Wapl differentially control cohesin chromosome association and function by Misulovin, Ziva, Pherson, Michelle, Gause, Maria, Dorsett, Dale

“…The cohesin complex topologically encircles chromosomes and mediates sister chromatid cohesion to ensure accurate chromosome segregation upon cell division…”
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Histone H3K4 monomethylation catalyzed by Trr and mammalian COMPASS-like proteins at enhancers is dispensable for development and viability by Rickels, Ryan, Herz, Hans-Martin, Sze, Christie C, Cao, Kaixiang, Morgan, Marc A, Collings, Clayton K, Gause, Maria, Takahashi, Yoh-hei, Wang, Lu, Rendleman, Emily J, Marshall, Stacy A, Krueger, Annika, Bartom, Elizabeth T, Piunti, Andrea, Smith, Edwin R, Abshiru, Nebiyu A, Kelleher, Neil L, Dorsett, Dale, Shilatifard, Ali

“…Ali Shilatifard and colleagues generate Drosophila lines expressing catalytically deficient Trr, which normally deposits H3K4me1 at enhancers. Trr mutants…”
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A Cell-Intrinsic Interferon-like Response Links Replication Stress to Cellular Aging Caused by Progerin by Kreienkamp, Ray, Graziano, Simona, Coll-Bonfill, Nuria, Bedia-Diaz, Gonzalo, Cybulla, Emily, Vindigni, Alessandro, Dorsett, Dale, Kubben, Nard, Batista, Luis Francisco Zirnberger, Gonzalo, Susana

“…Hutchinson-Gilford progeria syndrome (HGPS) is a premature aging disease caused by a truncated lamin A protein (progerin) that drives cellular and organismal…”
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On the Molecular Etiology of Cornelia de Lange Syndrome by Dorsett, Dale, Krantz, Ian D.

“…Cornelia de Lange syndrome (CdLS) is genetically heterogeneous and is usually sporadic, occurring approximately once per 10,000 births. CdLS individuals…”
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Dosage-Sensitive Regulation of Cohesin Chromosome Binding and Dynamics by Nipped-B, Pds5, and Wapl by Gause, Maria, Misulovin, Ziva, Bilyeu, Amy, Dorsett, Dale

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Germline gain-of-function mutations in AFF4 cause a developmental syndrome functionally linking the super elongation complex and cohesin by Izumi, Kosuke, Nakato, Ryuichiro, Zhang, Zhe, Edmondson, Andrew C, Noon, Sarah, Dulik, Matthew C, Rajagopalan, Ramakrishnan, Venditti, Charles P, Gripp, Karen, Samanich, Joy, Zackai, Elaine H, Deardorff, Matthew A, Clark, Dinah, Allen, Julian L, Dorsett, Dale, Misulovin, Ziva, Komata, Makiko, Bando, Masashige, Kaur, Maninder, Katou, Yuki, Shirahige, Katsuhiko, Krantz, Ian D

“…Ian Krantz, Katsuhiko Shirahige and colleagues report the genetic characterization of a new clinical syndrome characterized by cognitive impairment, heart and…”
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Cohesin and polycomb proteins functionally interact to control transcription at silenced and active genes by Schaaf, Cheri A, Misulovin, Ziva, Gause, Maria, Koenig, Amanda, Gohara, David W, Watson, Audrey, Dorsett, Dale

“…Cohesin is crucial for proper chromosome segregation but also regulates gene transcription and organism development by poorly understood mechanisms. Using…”
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Genome-wide control of RNA polymerase II activity by cohesin by Schaaf, Cheri A, Kwak, Hojoong, Koenig, Amanda, Misulovin, Ziva, Gohara, David W, Watson, Audrey, Zhou, Yanjiao, Lis, John T, Dorsett, Dale

“…Cohesin is a well-known mediator of sister chromatid cohesion, but it also influences gene expression and development. These non-canonical roles of cohesin are…”
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Drosophila TDP-43 RNA-Binding Protein Facilitates Association of Sister Chromatid Cohesion Proteins with Genes, Enhancers and Polycomb Response Elements by Swain, Amanda, Misulovin, Ziva, Pherson, Michelle, Gause, Maria, Mihindukulasuriya, Kathie, Rickels, Ryan A, Shilatifard, Ali, Dorsett, Dale

“…The cohesin protein complex mediates sister chromatid cohesion and participates in transcriptional control of genes that regulate growth and development…”
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Sall1 balances self-renewal and differentiation of renal progenitor cells by Basta, Jeannine M, Robbins, Lynn, Kiefer, Susan M, Dorsett, Dale, Rauchman, Michael

“…The formation of the proper number of functional nephrons requires a delicate balance between renal progenitor cell self-renewal and differentiation. The…”
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Positive regulation of c- Myc by cohesin is direct, and evolutionarily conserved by Rhodes, Jenny M., Bentley, Fiona K., Print, Cristin G., Dorsett, Dale, Misulovin, Ziva, Dickinson, Emma J., Crosier, Kathryn E., Crosier, Philip S., Horsfield, Julia A.

“…Contact between sister chromatids from S phase to anaphase depends on cohesin, a large multi-subunit protein complex. Mutations in sister chromatid cohesion…”
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Drosophila Nipped-B Protein Supports Sister Chromatid Cohesion and Opposes the Stromalin/Scc3 Cohesion Factor To Facilitate Long-Range Activation of the cut Gene by Rollins, Robert A., Korom, Maria, Aulner, Nathalie, Martens, Andrew, Dorsett, Dale

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Regulation of the Drosophila Enhancer of split and invected-engrailed gene complexes by sister chromatid cohesion proteins by Schaaf, Cheri A, Misulovin, Ziva, Sahota, Gurmukh, Siddiqui, Akbar M, Schwartz, Yuri B, Kahn, Tatyana G, Pirrotta, Vincenzo, Gause, Maria, Dorsett, Dale

“…The cohesin protein complex was first recognized for holding sister chromatids together and ensuring proper chromosome segregation. Cohesin also regulates gene…”
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Drosophila Nipped-B Mutants Model Cornelia de Lange Syndrome in Growth and Behavior by Wu, Yaning, Gause, Maria, Xu, Dongbin, Misulovin, Ziva, Schaaf, Cheri A, Mosarla, Ramya C, Mannino, Elizabeth, Shannon, Megan, Jones, Emily, Shi, Mi, Chen, Wen-Feng, Katz, Olivia L, Sehgal, Amita, Jongens, Thomas A, Krantz, Ian D, Dorsett, Dale

“…Individuals with Cornelia de Lange Syndrome (CdLS) display diverse developmental deficits, including slow growth, multiple limb and organ abnormalities, and…”
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Cohesin: genomic insights into controlling gene transcription and development by Dorsett, Dale

“…Over the past decade it has emerged that the cohesin protein complex, which functions in sister chromatid cohesion, chromosome segregation, and DNA repair,…”
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The Many Roles of Cohesin in Drosophila Gene Transcription by Dorsett, Dale

“…The cohesin protein complex mediates sister chromatid cohesion to ensure accurate chromosome segregation, and also influences gene transcription in higher…”
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The Drosophila MI-2 chromatin-remodeling factor regulates higher-order chromatin structure and cohesin dynamics in vivo by Fasulo, Barbara, Deuring, Renate, Murawska, Magdalena, Gause, Maria, Dorighi, Kristel M, Schaaf, Cheri A, Dorsett, Dale, Brehm, Alexander, Tamkun, John W

“…dMi-2 is a highly conserved ATP-dependent chromatin-remodeling factor that regulates transcription and cell fates by altering the structure or positioning of…”
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Effects of sister chromatid cohesion proteins on cut gene expression during wing development in Drosophila by Dorsett, Dale, Eissenberg, Joel C, Misulovin, Ziva, Martens, Andrew, Redding, Bethany, McKim, Kim

“…The cohesin protein complex is a conserved structural component of chromosomes. Cohesin binds numerous sites along interphase chromosomes and is essential for…”
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