Search Results - "Dorresteijn, Bram"
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1
Etiological Role of Viruses in Outbreaks of Acute Gastroenteritis in The Netherlands from 1994 through 2005
Published in Journal of Clinical Microbiology (01-05-2007)“…Acute gastroenteritis is one of the most common diseases worldwide. In developed countries, viruses, particularly noroviruses, are recognized as the leading…”
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2
Whey-based diet containing medium chain triglycerides modulates the gut microbiota and protects the intestinal mucosa from chemotherapy while maintaining therapy efficacy
Published in Cell death & disease (23-05-2023)“…Cytotoxicity (i.e. cell death) is the core mechanism by which chemotherapy induces its anti-cancer effects. Unfortunately, this same mechanism underpins the…”
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3
Impact of different palliative systemic treatments on skeletal muscle mass in metastatic colorectal cancer patients
Published in Journal of cachexia, sarcopenia and muscle (01-10-2018)“…Background Observational studies suggest that loss of skeletal muscle mass (SMM) is associated with chemotherapy‐related toxicity, poor quality of life, and…”
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4
The association between changes in muscle mass and quality of life in patients with metastatic colorectal cancer
Published in Journal of cachexia, sarcopenia and muscle (01-08-2020)“…Background Skeletal muscle mass (SMM) loss is common in metastatic colorectal cancer (mCRC) patients and associated with poor clinical outcomes, including…”
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5
Specialized nutrition improves muscle function and physical activity without affecting chemotherapy efficacy in C26 tumour‐bearing mice
Published in Journal of cachexia, sarcopenia and muscle (01-06-2021)“…Background Skeletal muscle wasting and fatigue are commonly observed in cancer patients receiving chemotherapy and associated with reduced treatment outcome…”
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6
Loss of skeletal muscle index and survival in patients with metastatic colorectal cancer: Secondary analysis of the phase 3 CAIRO3 trial
Published in Cancer medicine (Malden, MA) (01-02-2020)“…Background Low skeletal muscle index (SMI) in metastatic colorectal cancer (mCRC) patients is associated with poor outcomes. The prognostic impact of SMI…”
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7
Nanobody-based cancer therapy of solid tumors
Published in Nanomedicine (London, England) (01-01-2015)“…The development of tumor-targeted therapies using monoclonal antibodies has been successful during the last 30 years. Nevertheless, the efficacy of…”
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8
Homogeneous tumor targeting with a single dose of HER2-targeted albumin-binding domain-fused nanobody-drug conjugates results in long-lasting tumor remission in mice
Published in Theranostics (01-01-2021)“…The non-homogenous distribution of antibody-drug conjugates (ADCs) within solid tumors is a major limiting factor for their wide clinical application…”
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9
DPA shows comparable chemotherapy sensitizing effects as EPA upon cellular incorporation in tumor cells
Published in Oncotarget (15-10-2019)“…Dietary supplementation with ω-3 polyunsaturated fatty acids (PUFAs) has been reported to enhance the sensitivity of tumor cells towards chemotherapy. Most…”
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10
Trajectory of body mass and skeletal muscle indices and disease progression in metastatic colorectal cancer patients
Published in The American journal of clinical nutrition (01-12-2019)“…Knowledge of the evolution of BMI and skeletal muscle index (SMI) measurements during advanced cancer and their relationships with disease progression (PD) is…”
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11
In vitro chemotherapy-associated muscle toxicity is attenuated with nutritional support, while treatment efficacy is retained
Published in Oncotarget (08-10-2022)“…PURPOSEMuscle-wasting and treatment-related toxicities negatively impact prognosis of colorectal cancer (CRC) patients. Specific nutritional composition might…”
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12
Hypoxia-Targeting Fluorescent Nanobodies for Optical Molecular Imaging of Pre-Invasive Breast Cancer
Published in Molecular imaging and biology (01-08-2016)“…Purpose The aim of this work was to develop a CAIX-specific nanobody conjugated to IRDye800CW for molecular imaging of pre-invasive breast cancer. Procedures…”
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13
Camelid heavy chain only antibody fragment domain against β‐site of amyloid precursor protein cleaving enzyme 1 inhibits β‐secretase activity in vitro and in vivo
Published in The FEBS journal (01-09-2015)“…Accumulation and aggregation of the amyloid‐β (Aβ) peptide is associated with Alzheimer's disease (AD). Aβ is generated from the amyloid precursor protein by…”
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14
Camelid heavy chain only antibody fragment domain against [beta]-site of amyloid precursor protein cleaving enzyme 1 inhibits [beta]-secretase activity in vitro and in vivo
Published in The FEBS journal (01-09-2015)“…Accumulation and aggregation of the amyloid-[beta] (A[beta]) peptide is associated with Alzheimer's disease (AD). A[beta] is generated from the amyloid…”
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15
Specialized Nutritional Support Improves Muscle Function and Maintains Physical Activity Without Affecting Chemotherapy Efficacy in a Colorectal Cancer Mouse Model
Published in Current developments in nutrition (01-06-2021)“…Skeletal muscle wasting and fatigue are commonly observed in cancer patients receiving chemotherapy and are associated with reduced treatment outcome and…”
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16
Impact of skeletal muscle index (SMI) loss during palliative systemic treatment (Tx) on time to progression and overall survival (OS) in metastatic colorectal cancer (mCRC) patients
Published in Journal of clinical oncology (20-05-2017)“…Abstract only 10087 Background: Evidence for a strong link between skeletal muscle depletion and poor outcomes in mCRC is growing. However, the impact of SMI…”
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