Search Results - "Doroudi, Maryam"

Substrate Stiffness Controls Osteoblastic and Chondrocytic Differentiation of Mesenchymal Stem Cells without Exogenous Stimuli by Olivares-Navarrete, Rene, Lee, Erin M, Smith, Kathryn, Hyzy, Sharon L, Doroudi, Maryam, Williams, Joseph K, Gall, Ken, Boyan, Barbara D, Schwartz, Zvi

“…Stem cell fate has been linked to the mechanical properties of their underlying substrate, affecting mechanoreceptors and ultimately leading to downstream…”
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Association of Colonoscopy Adenoma Findings With Long-term Colorectal Cancer Incidence by Click, Benjamin, Pinsky, Paul F, Hickey, Tom, Doroudi, Maryam, Schoen, Robert E

“…IMPORTANCE: Individuals with adenomatous polyps are advised to undergo repeated colonoscopy surveillance to prevent subsequent colorectal cancer (CRC), but the…”
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Membrane-mediated actions of 1,25-dihydroxy vitamin D3: a review of the roles of phospholipase A2 activating protein and Ca(2+)/calmodulin-dependent protein kinase II by Doroudi, Maryam, Schwartz, Zvi, Boyan, Barbara D

“…The secosteroid 1α,25-dihydroxy vitamin D3 [1α,25(OH)2D3] acts on cells via classical steroid hormone receptor-mediated gene transcription and by initiating…”
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Flexible sigmoidoscopy in the randomized prostate, lung, colorectal, and ovarian (PLCO) cancer screening trial: Colorectal cancer survival by trial arm by Doroudi, Maryam, Pinsky, Paul F

“…Abstract only…”
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Plasma membrane Pdia3 and VDR interact to elicit rapid responses to 1α,25(OH)2D3 by Chen, Jiaxuan, Doroudi, Maryam, Cheung, Jeffery, Grozier, Ashley L., Schwartz, Zvi, Boyan, Barbara D.

“…1α,25-Dihydroxyvitamin D3 (1α,25(OH)2D3) regulates osteoblasts through genomic and rapid membrane-mediated responses. Here we examined the interaction of…”
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Early detection versus primary prevention in the PLCO flexible sigmoidoscopy screening trial: Which has the greatest impact on mortality? by Doroudi, Maryam, Schoen, Robert E., Pinsky, Paul F.

“…BACKGROUND Screening for colorectal cancer (CRC) with flexible sigmoidoscopy (FS) has been shown to reduce CRC mortality. The current study examined whether…”
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Colorectal Cancer Screening by Pinsky, Paul F, Doroudi, Maryam

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Early detection versus prevention in the PLCO flexible sigmoidoscopy screening trial: Which had the greatest impact on mortality? by Doroudi, Maryam, Schoen, Robert E., Pinsky, Paul F.

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Is cancer history associated with asset ownership, debt, and net worth in the United States? by Doroudi, Maryam, Coughlan, Diarmuid, Banegas, Matthew P., Yabroff, K Robin

“…Abstract only e18085 Background: Financial hardships experienced by cancer survivors in the United States have become significant social and public health…”
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Phospholipase A2 activating protein is required for 1α,25-dihydroxyvitamin D3 dependent rapid activation of protein kinase C via Pdia3 by Doroudi, Maryam, Schwartz, Zvi, Boyan, Barbara D.

“…► PLAA and Pdia3 are localized to caveolae. ► PLAA interacts with Pdia3 receptor complex in presence of 1α,25(OH)2D3. ► Blocking PLAA with PLAA-antibody…”
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A review of 1α,25(OH)2D3 dependent Pdia3 receptor complex components in Wnt5a non-canonical pathway signaling by Doroudi, Maryam, Olivares-Navarrete, Rene, Boyan, Barbara D., Schwartz, Zvi

“…•Wnt5a signals via activation of CaMKII, PLA2, and PKC.•Pdia3, PLAA, and CaM are required for Wnt5a signaling.•ROR2 is required for 1α,25(OH)2D3-dependent PKC…”
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Membrane actions of 1α,25(OH)2D3 are mediated by Ca(2+)/calmodulin-dependent protein kinase II in bone and cartilage cells by Doroudi, Maryam, Plaisance, Marc C, Boyan, Barbara D, Schwartz, Zvi

“…1α,25(OH)2D3 regulates osteoblasts and chondrocytes via its membrane-associated receptor, protein disulfide isomerase A3 (Pdia3) in caveolae. 1α,25(OH)2D3…”
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Membrane-mediated actions of 1,25-dihydroxy vitamin D3: A review of the roles of phospholipase A2 activating protein and Ca2+/calmodulin-dependent protein kinase II by Doroudi, Maryam, Schwartz, Zvi, Boyan, Barbara D.

“…•Silencing Camk2a inhibits 1α,25(OH)2D3-stimulated PLA2 and PKC activation.•Silencing PLAA inhibits 1α,25(OH)2D3-stimulated CaMKII, PLA2 and PKC…”
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Signaling components of the 1α,25(OH)2D3-dependent Pdia3 receptor complex are required for Wnt5a calcium-dependent signaling by Doroudi, Maryam, Olivares-Navarrete, Rene, Hyzy, Sharon L., Boyan, Barbara D., Schwartz, Zvi

“…Wnt5a and 1α,25(OH)2D3 are important regulators of endochondral ossification. In osteoblasts and growth plate chondrocytes, 1α,25(OH)2D3 initiates rapid…”
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New insights on membrane mediated effects of 1α,25-dihydroxy vitamin D3 signaling in the musculoskeletal system by Doroudi, Maryam, Chen, Jiaxuan, Boyan, Barbara D., Schwartz, Zvi

“…1α,25-Dihydroxy vitamin D3 [1α,25(OH)2D3] acts on cells via classical steroid hormone receptor-mediated gene transcription and by initiating rapid…”
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The bimanual ovarian palpation examination in the Prostate, Lung, Colorectal and Ovarian cancer screening trial: Performance and complications by Doroudi, Maryam, Kramer, Barnett S, Pinsky, Paul F

“…Objective To provide evidence about the performance characteristics and consequences of bimanual ovarian palpation. Setting and methods The Prostate, Lung,…”
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956 - Long Term Risk of Colorectal Cancer After Detection of Adenomatous Polyps by Click, Benjamin H., Doroudi, Maryam, Hickey, Tom, Pinsky, Paul, Schoen, Robert E.

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Lung Cancer Mortality in the Lung Screening Study Feasibility Trial by Doroudi, Maryam, Pinsky, Paul F, Marcus, Pamela M

“…Abstract The Lung Screening Study was a multicenter controlled feasibility trial that randomly assigned subjects to undergo two rounds of screening with either…”
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Long Term Risk of Colorectal Cancer After Detection of Adenomatous Polyps by Click, Benjamin H, Doroudi, Maryam, Hickey, Tom, Pinsky, Paul, Schoen, Robert E

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Membrane actions of 1α,25(OH)2D3 are mediated by Ca2+/calmodulin-dependent protein kinase II in bone and cartilage cells by Doroudi, Maryam, Plaisance, Marc C., Boyan, Barbara D., Schwartz, Zvi

“…•1α,25(OH)2D3-dependent CaMKII activation requires Pdia3, PLAA, Cav-1 and caveolae.•CaMKII and CaM mediate signaling from 1α,25(OH)2D3-Pdia3 complexes to…”
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