Search Results - "Doroudchi, Mohammad M"

Induction of multiple heat shock proteins and neuroprotection in a primary culture model of familial amyotrophic lateral sclerosis by Batulan, Zarah, Taylor, David M., Aarons, Rebecca J., Minotti, Sandra, Doroudchi, Mohammad M., Nalbantoglu, Josephine, Durham, Heather D.

“…High threshold for stress-induced activation of the heat shock transcription factor, Hsf1, may contribute to vulnerability of motor neurons to disease and…”
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Novel Caprine Adeno-Associated Virus (AAV) Capsid (AAV-Go.1) Is Closely Related to the Primate AAV-5 and Has Unique Tropism and Neutralization Properties by Arbetman, Alejandra E, Lochrie, Michael, Zhou, Shangzhen, Wellman, Jennifer, Scallan, Ciaran, Doroudchi, Mohammad M, Randlev, Britta, Patarroyo-White, Susannah, Liu, Tongyao, Smith, Peter, Lehmkuhl, Howard, Hobbs, Lea Ann, Pierce, Glenn F, Colosi, Peter

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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High Threshold for Induction of the Stress Response in Motor Neurons Is Associated with Failure to Activate HSF1 by Batulan, Zarah, Shinder, Gayle A, Minotti, Sandra, He, Bei Ping, Doroudchi, Mohammad M, Nalbantoglu, Josephine, Strong, Michael J, Durham, Heather D

“…Heat shock protein 70 (Hsp70) protects cultured motor neurons from the toxic effects of mutations in Cu/Zn-superoxide dismutase (SOD-1), which is responsible…”
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A Neurotoxic Peripherin Splice Variant in a Mouse Model of ALS by Robertson, Janice, Doroudchi, Mohammad M., Nguyen, Minh Dang, Durham, Heather D., Strong, Michael J., Shaw, Gerry, Julien, Jean-Pierre, Mushynski, Walter E.

“…Peripherin, a neuronal intermediate filament (nIF) protein found associated with pathological aggregates in motor neurons of patients with amyotrophic lateral…”
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Striatal Delivery of rAAV-hAADC to Rats with Preexisting Immunity to AAV by Sanftner, Laura M, Suzuki, Brian M, Doroudchi, Mohammad M, Feng, Lan, McClelland, Alan, Forsayeth, John R, Cunningham, Janet

“…We tested the hypotheses that initial immunization of rats with rAAV might limit subsequent transduction by rAAV-hAADC when stereotaxically infused into the…”
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Apoptotic Death of Neurons Exhibiting Peripherin Aggregates Is Mediated by the Proinflammatory Cytokine Tumor Necrosis Factor-α by Robertson, Janice, Beaulieu, Jean-Martin, Doroudchi, Mohammad M., Durham, Heather D., Julien, Jean-Pierre, Mushynski, Walter E.

“…Peripherin, a neuronal intermediate filament protein associated with axonal spheroids in amyotrophic lateral sclerosis (ALS), induces the selective…”
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1010. Developing a Potential Pain Therapy Using Engineered Zinc Finger Protein Repressors of the Sodium Channel PN3 by Tan, Siyuan, Doroudchi, Mohammad M., Zhong, Xiaohong, Qiao, Julie, Zhang, Steve, Gregory, Philip D.

“…The voltage-gated sodium channel PN3 (Nav1.8, SCN10a), expressed exclusively in sensory neurons located in dorsal root ganglia (DRG), is a key molecule in…”
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Adeno‐associated virus‐mediated gene transfer of human aromatic l‐amino acid decarboxylase protects mixed striatal primary cultures from l‐DOPA toxicity by Doroudchi, Mohammad M., Liauw, Jason, Heaton, Krista, Zhen, Zhu, Forsayeth, John R.

“…Although l‐DOPA is the drug of choice for Parkinson's disease, prolonged l‐DOPA therapy results in decreased drug effectiveness and the appearance of motor…”
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Expression of a membrane-bound form of the ferroxidase ceruloplasmin by leptomeningeal cells by Mittal, Bina, Doroudchi, Mohammad M., Jeong, Suh Young, Patel, Bharatkumar N., David, Samuel

“…Ceruloplasmin is a key enzyme involved in detoxifying ferrous iron, which can generate free radicals. The secreted form of ceruloplasmin is produced by the…”
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Nitrotyrosination contributes minimally to toxicity of mutant SOD1 associated with ALS by Doroudchi, Mohammad M, Minotti, Sandra, Figlewicz, Denise A, Durham, Heather D

“…Enhanced production of nitrotyrosine and subsequent protein nitration has been proposed as the mechanism by which mutant SOD1 causes death of motor neurons in…”
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Nitrotyrosination contributes minimally to toxicity of mutant SOD I associated with ALS by DOROUDCHI, Mohammad M, MINOTTI, Sandra, FIGLEWICZ, Denise A, DURHAM, Heather D

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Activation of NMDA receptors and Ca2+/calmodulin-dependent protein kinase participate in phosphorylation of neurofilaments induced by protein kinase C by Doroudchi, Mohammad M., Durham, Heather D.

“…Aberrant phosphorylation of neurofilaments, similar to that occurring in various motor neuron diseases, is produced in cultured motor neurons by activation of…”
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