Search Results - "Dorota Scibior‐Bentkowska"

DNA methylation testing with S5 for triage of high‐risk HPV positive women by Adcock, Rachael, Nedjai, Belinda, Lorincz, Attila T., Scibior‐Bentkowska, Dorota, Banwait, Rawinder, Torrez‐Martinez, Norah, Robertson, Michael, Cuzick, Jack, Wheeler, Cosette M.

“…Methylation of host and viral genes is promising for triage of women with high‐risk human papillomavirus infections (hrHPV). Using a population‐based sample of…”
Get full text

Long-term prediction by DNA methylation of high-grade cervical intraepithelial neoplasia: Results of the ARTISTIC cohort by Gilham, Clare, Nedjai, Belinda, Scibior-Bentkowska, Dorota, Reuter, Caroline, Banwait, Rawinder, Brentnall, Adam R, Cuzick, Jack, Peto, Julian, Lorincz, Attila T

“…Methylation markers have shown potential for triaging high-risk HPV-positive (hrHPV+) women to identify those at increased risk of invasive cervical cancer…”
Get full text

Validation of a DNA methylation HPV triage classifier in a screening sample by Lorincz, Attila T., Brentnall, Adam R., Scibior‐Bentkowska, Dorota, Reuter, Caroline, Banwait, Rawinder, Cadman, Louise, Austin, Janet, Cuzick, Jack, Vasiljević, Natasa

“…High‐risk human papillomavirus (hrHPV) DNA tests have excellent sensitivity for detection of cervical intraepithelial neoplasia 2 or higher (CIN2+). A drawback…”
Get full text

Low methylation marker levels among human papillomavirus-vaccinated women with cervical high-grade squamous intraepithelial lesions by Louvanto, Karolina, Verhoef, Lisanne, Pimenoff, Ville, Eriksson, Tiina, Leppälä, Siiri, Lagheden, Camilla, Gray, Penelope, Scibior-Bentkowska, Dorota, Sumiec, Elizabeth, Nieminen, Pekka, Dillner, Joakim, Berkhof, Johannes, Meijer, Chris J L M, Lehtinen, Matti, Nedjai, Belinda, Heideman, Daniëlle A M

“…Cervical cancer screening programs, including triage tests, need redesigning as human papillomavirus (HPV)-vaccinated women are entering the programs…”
Get full text

A DNA methylation classifier of cervical precancer based on human papillomavirus and human genes by Brentnall, Adam R., Vasiljević, Nataša, Scibior‐Bentkowska, Dorota, Cadman, Louise, Austin, Janet, Szarewski, Anne, Cuzick, Jack, Lorincz, Attila T.

“…Testing for high‐risk (hr) types of human papillomavirus (HPV) is highly sensitive as a screening test of high‐grade cervical intraepithelial neoplastic…”
Get full text

Clinical performance of methylation as a biomarker for cervical carcinoma in situ and cancer diagnosis: A worldwide study by Banila, Cristiana, Lorincz, Attila T., Scibior‐Bentkowska, Dorota, Clifford, Gary M., Kumbi, Birhanu, Beyene, Dereje, Wheeler, Cosette M., Cuschieri, Kate, Cuzick, Jack, Nedjai, Belinda

“…The shift towards primary human papillomavirus (HPV)‐based screening has necessitated the search for a secondary triage test that provides sufficient…”
Get full text

Elevated methylation of HPV16 DNA is associated with the development of high grade cervical intraepithelial neoplasia by Mirabello, Lisa, Schiffman, Mark, Ghosh, Arpita, Rodriguez, Ana C., Vasiljevic, Natasa, Wentzensen, Nicolas, Herrero, Rolando, Hildesheim, Allan, Wacholder, Sholom, Scibior‐Bentkowska, Dorota, Burk, Robert D., Lorincz, Attila T.

“…We explored the association of human papillomavirus type 16 (HPV16) DNA methylation with age, viral load, viral persistence and risk of incident and prevalent…”
Get full text

HPV16 L1 and L2 DNA methylation predicts high‐grade cervical intraepithelial neoplasia in women with mildly abnormal cervical cytology by Lorincz, Attila T, Brentnall, Adam R, Vasiljević, Nataša, Scibior‐Bentkowska, Dorota, Castanon, Alejandra, Fiander, Alison, Powell, Ned, Tristram, Amanda, Cuzick, Jack, Sasieni, Peter

“…DNA methylation changes in human papillomavirus type 16 (HPV16) DNA are common and might be important for identifying women at increased risk of cervical…”
Get full text

Methylation of viral and host genes and severity of cervical lesions associated with human papillomavirus type 16 by Louvanto, Karolina, Franco, Eduardo L., Ramanakumar, Agnihotram V., Vasiljević, Nataša, Scibior‐Bentkowska, Dorota, Koushik, Anita, Cuzick, Jack, Coutlée, Francois, Lorincz, Attila T.

“…Methylation of human papillomavirus (HPV) and host genes may predict cervical cancer risk. We examined the methylation status of selected sites in HPV16 and…”
Get full text

HPV33 DNA methylation measurement improves cervical pre-cancer risk estimation of an HPV16, HPV18, HPV31 and \textit{EPB41L3} methylation classifier by Brentnall, Adam R, Vasiljevic, Natasa, Scibior-Bentkowska, Dorota, Cadman, Louise, Austin, Janet, Cuzick, Jack, Lorincz, Attila T

“…Persistent infection %by with high risk human papillomavirus (hrHPV) types causes cervical cancer but most women who test positive are at very low risk of…”
Get more information

Credentialing of DNA methylation assays for human genes as diagnostic biomarkers of cervical intraepithelial neoplasia in high-risk HPV positive women by Vasiljević, Nataša, Scibior-Bentkowska, Dorota, Brentnall, Adam R, Cuzick, Jack, Lorincz, Attila T

“…Abstract Objective Testing for high risk human papillomavirus (HR-HPV) is increasing; however due to limitations in specificity there remains a need for better…”
Get full text

Clinical performance of methylation as a biomarker for cervical carcinoma insitu and cancer diagnosis: A worldwide study by Banila, Cristiana, Lorincz, Attila T, Dorota Scibior‐Bentkowska, Clifford, Gary M, Kumbi, Birhanu, Beyene, Dereje, Wheeler, Cosette M, Cuschieri, Kate, Cuzick, Jack, Nedjai, Belinda

“…The shift towards primary human papillomavirus (HPV)‐based screening has necessitated the search for a secondary triage test that provides sufficient…”
Get full text

A comparison of methylation levels in HPV18, HPV31 and HPV33 genomes reveals similar associations with cervical precancers by Vasiljević, Nataša, Scibior-Bentkowska, Dorota, Brentnall, Adam, Cuzick, Jack, Lorincz, Attila

“…Abstract Background High risk human papillomavirus (HR-HPV) infection is common and only a small minority of infections become persistent and lead to cervical…”
Get full text

Cancer cells and oxidative stress by Scibior-Bentkowska, Dorota, Czeczot, Hanna

“…Reactive oxygen species (ROS) formation are a constant element of a cell's oxygen metabolism. They are its normal products and in physiological concentrations…”
Get full text

Methylation estimates the risk of precancer in HPV-infected women with discrepant results between cytology and HPV16/18 genotyping by Hernández-López, Rubí, Lorincz, Attila T, Torres-Ibarra, Leticia, Reuter, Caroline, Scibior-Bentkowska, Dorota, Warman, Rhian, Nedjai, Belinda, Mendiola-Pastrana, Indira, León-Maldonado, Leith, Rivera-Paredez, Berenice, Ramírez-Palacios, Paula, Lazcano-Ponce, Eduardo, Cuzick, Jack, Salmerón, Jorge

“…Vigilant management of women with high-risk human papillomavirus (hrHPV) is necessary in cancer screening programs. To this end, we evaluated the performance…”
Get full text

Changes of the glutathione enzymatic redox system in human gastrointestinal tract tumours by Scibior-Bentkowska, Dorota, Skrzycki, Michal, Podsiad, Malgorzata, Czeczot, Hanna

“…Introduction: Glutathione (GSH) and GSH-dependent enzymes - glutathione peroxidase (GSHPx), glutathione S-transferase (GST) and glutathione reductase (GSHR) -…”
Get full text

Assessment of lipid peroxidation level in serum of patients with gastrointestinal tract tumors by Czeczot, Hanna, Scibior-Bentkowska, Dorota, Skrzycki, Michał, Podsiad, Małgorzata

“…Clinical and experimental studies indicate oxygen free radicals and their reactive derivatives participation in formation of chronic inflammation states, which…”
Get more information

Quantitative DNA methylation and recurrence of breast cancer: a study of 30 candidate genes by Cheol Kim, Dae, Thorat, Mangesh A, Lee, Mi Ri, Cho, Se Heon, Vasiljević, Nataša, Scibior-Bentkowska, Dorota, Wu, Keqiang, Ahmad, Amar S, Duffy, Stephen, Cuzick, Jack M, Lorincz, Attila T

“…The need for new prognostic factors in breast cancer is ever increasing as breast cancer management evolves. Aberrant DNA methylation plays a pivotal role in…”
Get more information

Lipid peroxidation level in gastrointestinal tract tumors by Czeczot, Hanna, Scibior-Bentkowska, Dorota, Skrzycki, Michał, Majewska, Monika, Podsiad, Małgorzata

“…Oxygen free radicals and their reactive derivatives participate in formation of chronic inflammation states, which facilitate development of gastrointestinal…”
Get more information

Protein level of transcription factors AP-1 and NF-kappaB in selected human gastrointestinal tract tumors by Skrzycki, Michał, Scibior-Bentkowska, Dorota, Podsiad, Małgorzata, Czeczot, Hanna

“…Transcription factors AP-1 and NF-kappaB control important cell processes like proliferation, apoptosis and differentiation. Disturbance of this processes is…”
Get more information