Search Results - "Dorniak, Piotr L."
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Calcium-mediated oxidative stress: a common mechanism in tight junction disruption by different types of cellular stress
Published in Biochemical journal (20-02-2017)“…The role of reactive oxygen species (ROS) in osmotic stress, dextran sulfate sodium (DSS) and cyclic stretch-induced tight junction (TJ) disruption was…”
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Role of CTGF in Sensitivity to Hyperthermia in Ovarian and Uterine Cancers
Published in Cell reports (Cambridge) (01-11-2016)“…Even though hyperthermia is a promising treatment for cancer, the relationship between specific temperatures and clinical benefits and predictors of…”
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Improving vascular maturation using noncoding RNAs increases antitumor effect of chemotherapy
Published in JCI insight (08-04-2021)Get full text
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Adrenergic Stimulation of DUSP1 Impairs Chemotherapy Response in Ovarian Cancer
Published in Clinical cancer research (01-04-2016)“…Chronic adrenergic activation has been shown to associate with adverse clinical outcomes in cancer patients, but the underlying mechanisms are not well…”
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SnapShot: Stress and Disease
Published in Cell metabolism (09-02-2016)“…Perturbation of an organism’s homeostasis by stress can trigger biological or behavioral adaptation and accelerate onset and course of several diseases…”
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Antitumor and Antiangiogenic Effects of Aspirin-PC in Ovarian Cancer
Published in Molecular cancer therapeutics (01-12-2016)“…To determine the efficacy of a novel and safer (for gastrointestinal tract) aspirin (aspirin-PC) in preclinical models of ovarian cancer, in vitro…”
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Role of YAP1 as a Marker of Sensitivity to Dual AKT and P70S6K Inhibition in Ovarian and Uterine Malignancies
Published in JNCI : Journal of the National Cancer Institute (01-07-2017)“…The PI3K/AKT/P70S6K pathway is an attractive therapeutic target in ovarian and uterine malignancies because of its high rate of deregulation and key roles in…”
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PTEN Expression as a Predictor of Response to Focal Adhesion Kinase Inhibition in Uterine Cancer
Published in Molecular cancer therapeutics (01-06-2015)“…PTEN is known to be frequently mutated in uterine cancer and also dephosphorylates FAK. Here, we examined the impact of PTEN alterations on the response to…”
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Improving vascular maturation using noncoding RNAs increases antitumor effect of chemotherapy
Published in JCI insight (20-10-2016)“…Current antiangiogenesis therapy relies on inhibiting newly developed immature tumor blood vessels and starving tumor cells. This strategy has shown transient…”
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10
Improving vascular maturation using noncoding RNAs increases antitumor effect of chemotherapy
Published in JCI insight (07-06-2018)Get full text
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11
Sustained adrenergic signaling leads to increased metastasis in ovarian cancer via increased PGE2 synthesis
Published in Oncogene (05-05-2016)“…Adrenergic stimulation adversely affects tumor growth and metastasis, but the underlying mechanisms are not well understood. Here, we uncovered a novel…”
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Interferon Tau, Prostaglandins, and Cortisol Coordinately Regulate Endometrial Function and Conceptus Elongation in Sheep
Published in Biology of reproduction (01-08-2012)Get full text
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Abstract 4144: Role of CTGF in hyperthermia resistance in ovarian and uterine cancers
Published in Cancer research (Chicago, Ill.) (01-07-2017)“…Abstract Objective. Even though hyperthermia is a promising treatment for cancer, multiple obstacles remain to be cleared. Among these, the tumor temperatures…”
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Prostaglandins Regulate Endometrial Function in Sheep
Published in Biology of reproduction (01-07-2011)Get full text
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Anti-tumor and Anti-angiogenic Effects of Aspirin-PC in Ovarian Cancer
Published in Molecular cancer therapeutics (16-09-2016)“…To determine the efficacy of a novel and safer (for gastrointestinal tract) aspirin (aspirin-PC) in preclinical models of ovarian cancer, in vitro…”
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Potential Roles for HSD11B1 and Cortisol in Regulation of Endometrial Functions and Conceptus Elongation in Sheep
Published in Biology of reproduction (01-07-2011)Get full text
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Hydroxysteroid (11-beta) Dehydrogenase (HSD11B1) Activity in the Ovine Endometrium and Conceptus During Early Pregnancy
Published in Biology of reproduction (01-11-2010)Get full text
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