Search Results - "Dorner, Martin B."

Molecular basis for disruption of E-cadherin adhesion by botulinum neurotoxin A complex by Lee, Kwangkook, Zhong, Xiaofen, Gu, Shenyan, Kruel, Anna Magdalena, Dorner, Martin B., Perry, Kay, Rummel, Andreas, Dong, Min, Jin, Rongsheng

“…How botulinum neurotoxins (BoNTs) cross the host intestinal epithelial barrier in foodborne botulism is poorly understood. Here, we present the crystal…”
Get full text

Construction and validation of safe Clostridium botulinum Group II surrogate strain producing inactive botulinum neurotoxin type E toxoid by Nowakowska, Maria B., Selby, Katja, Przykopanski, Adina, Krüger, Maren, Krez, Nadja, Dorner, Brigitte G., Dorner, Martin B., Jin, Rongsheng, Minton, Nigel P., Rummel, Andreas, Lindström, Miia

“…Botulinum neurotoxins (BoNTs), produced by the spore-forming bacterium Clostridium botulinum , cause botulism, a rare but fatal illness affecting humans and…”
Get full text

Strengthening the United Nations Secretary-General’s Mechanism to an alleged use of bioweapons through a quality-assured laboratory response by Appelt, Sandra, Rohleder, Anna-Maria, Invernizzi, Cédric, Mikulak, Robert, Brinkmann, Annika, Nitsche, Andreas, Krüger, Maren, Dorner, Martin B., Dorner, Brigitte G., Scholz, Holger C., Grunow, Roland

“…The cascade of innovations in biotechnology opens new pathways for biological warfare. The international laboratory network being developed under the UN…”
Get full text

Isolation and functional characterization of the novel Clostridium botulinum neurotoxin A8 subtype by Kull, Skadi, Schulz, K Melanie, Weisemann, Jasmin, Kirchner, Sebastian, Schreiber, Tanja, Bollenbach, Alexander, Dabrowski, P Wojtek, Nitsche, Andreas, Kalb, Suzanne R, Dorner, Martin B, Barr, John R, Rummel, Andreas, Dorner, Brigitte G

“…Botulism is a severe neurological disease caused by the complex family of botulinum neurotoxins (BoNT). Based on the different serotypes known today, a…”
Get full text

Vaccine-induced neutralizing antibodies bind to the H protein of a historical measles virus by Zemella, Anne, Beer, Kerstin, Ramm, Franziska, Wenzel, Dana, Düx, Ariane, Merkel, Kevin, Calvignac-Spencer, Sebastien, Stern, Daniel, Dorner, Martin B., Dorner, Brigitte G., Widulin, Navena, Schnalke, Thomas, Walter, Cornelia, Wolbert, Anne, Schmid, Bernhard G., Mankertz, Annette, Santibanez, Sabine

“…Measles is a highly contagious airborne viral disease. It can lead to serious complications and death and is preventable by vaccination. The live-attenuated…”
Get full text

A Novel Prophage-like Insertion Element within yabG Triggers Early Entry into Sporulation in Clostridium botulinum by Douillard, François P, Portinha, Inês Martins, Derman, Yağmur, Woudstra, Cédric, Mäklin, Tommi, Dorner, Martin B, Korkeala, Hannu, Henriques, Adriano O, Lindström, Miia

“…Sporulation is a finely regulated morphogenetic program important in the ecology and epidemiology of . Exogenous elements disrupting sporulation-associated…”
Get full text

Ricinus communis intoxications in human and veterinary medicine-a summary of real cases by Worbs, Sylvia, Köhler, Kernt, Pauly, Diana, Avondet, Marc-André, Schaer, Martin, Dorner, Martin B, Dorner, Brigitte G

“…Accidental and intended Ricinus communis intoxications in humans and animals have been known for centuries but the causative agent remained elusive until 1888…”
Get full text

Genomic and Phenotypic Characterization of Clostridium botulinum Isolates from an Infant Botulism Case Suggests Adaptation Signatures to the Gut by Douillard, François P, Derman, Yağmur, Woudstra, Cédric, Selby, Katja, Mäklin, Tommi, Dorner, Martin B, Saxén, Harri, Dorner, Brigitte G, Korkeala, Hannu, Lindström, Miia

“…In early life, the immature human gut microbiota is prone to colonization by pathogens that are usually outcompeted by mature microbiota in the adult gut…”
Get full text

Differentiation, Quantification and Identification of Abrin and Abrus precatorius Agglutinin by Worbs, Sylvia, Kampa, Bettina, Skiba, Martin, Hansbauer, Eva-Maria, Stern, Daniel, Volland, Hervé, Becher, François, Simon, Stéphanie, Dorner, Martin B, Dorner, Brigitte G

“…Abrin, the toxic lectin from the rosary pea plant has gained considerable interest in the recent past due to its potential malevolent use. However, reliable…”
Get full text

Real-time cytotoxicity assay for rapid and sensitive detection of ricin from complex matrices by Pauly, Diana, Worbs, Sylvia, Kirchner, Sebastian, Shatohina, Olena, Dorner, Martin B, Dorner, Brigitte G

“…In the context of a potential bioterrorist attack sensitive and fast detection of functionally active toxins such as ricin from complex matrices is necessary…”
Get full text

Development of a Genus-Specific Antigen Capture ELISA for Orthopoxviruses - Target Selection and Optimized Screening by Stern, Daniel, Pauly, Diana, Zydek, Martin, Miller, Lilija, Piesker, Janett, Laue, Michael, Lisdat, Fred, Dorner, Martin B, Dorner, Brigitte G, Nitsche, Andreas

“…Orthopoxvirus species like cowpox, vaccinia and monkeypox virus cause zoonotic infections in humans worldwide. Infections often occur in rural areas lacking…”
Get full text

Selection and Development of Nontoxic Nonproteolytic Clostridium botulinum Surrogate Strains for Food Challenge Testing by Poortmans, Marijke, Vanoirbeek, Kristof, Dorner, Martin B, Michiels, Chris W

“…causes severe foodborne intoxications by producing a potent neurotoxin. Challenge studies with this pathogen are an important tool to ensure the safety of new…”
Get full text

Clinical findings and outcome in feline tetanus: a multicentric retrospective study of 27 cases and review of the literature by Dussaux, Alice, Fuhrer, Laurent, Dorner, Martin B, Santifort, Koen, Vanhaesebrouck, An, Menchetti, Marika, Danciu, Cecilia-Gabriella, Dutil, Guillaume, Escriou, Catherine, Blot, Stephane, Gutmann, Sarah, Taestensen, Carina, Mayousse, Vincent

“…Tetanus is a toxigenic illness caused by the action of neurotoxin (TeNT), which results in partial or generalized muscle stiffness in infected mammals and…”
Get full text

Development and Evaluation of an Immuno-MALDI-TOF Mass Spectrometry Approach for Quantification of the Abrin Toxin in Complex Food Matrices by Livet, Sandrine, Worbs, Sylvia, Volland, Hervé, Simon, Stéphanie, Dorner, Martin B, Fenaille, François, Dorner, Brigitte G, Becher, François

“…The toxin abrin found in the seeds of has attracted much attention regarding criminal and terroristic misuse over the past decade. Progress in analytical…”
Get full text

Pentaplexed Quantitative Real-Time PCR Assay for the Simultaneous Detection and Quantification of Botulinum Neurotoxin-Producing Clostridia in Food and Clinical Samples by KIRCHNER, Sebastian, KRÄMER, K. Melanie, SCHULZE, Martin, PAULY, Diana, JACOB, Daniela, GESSLER, Frank, NITSCHE, Andreas, DORNER, Brigitte G, DORNER, Martin B

“…Classifications Services AEM Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
Get full text

Innovative and Highly Sensitive Detection of Clostridium perfringens Enterotoxin Based on Receptor Interaction and Monoclonal Antibodies by Neumann, Thea, Krüger, Maren, Weisemann, Jasmin, Mahrhold, Stefan, Stern, Daniel, Dorner, Martin B, Feraudet-Tarisse, Cécile, Pöhlmann, Christopher, Schulz, Katharina, Messelhäußer, Ute, Rimek, Dagmar, Gessler, Frank, Elßner, Thomas, Simon, Stéphanie, Rummel, Andreas, Dorner, Brigitte G

“…enterotoxin (CPE) regularly causes food poisoning and antibiotic-associated diarrhea; therefore, reliable toxin detection is crucial. To this aim, we explored…”
Get full text

Simultaneous quantification of five bacterial and plant toxins from complex matrices using a multiplexed fluorescent magnetic suspension assay by Pauly, Diana, Kirchner, Sebastian, Stoermann, Britta, Schreiber, Tanja, Kaulfuss, Stefan, Schade, Rüdiger, Zbinden, Reto, Avondet, Marc-André, Dorner, Martin B, Dorner, Brigitte G

“…Proteotoxins such as ricin, abrin, botulinum neurotoxins type A and B (BoNT/A, BoNT/B) and staphylococcal enterotoxin B (SEB) are regarded as potential…”
Get more information

Multiplex Detection of Microbial and Plant Toxins by Immunoaffinity Enrichment and Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry by Kull, Skadi, Pauly, Diana, Störmann, Britta, Kirchner, Sebastian, Stämmler, Maren, Dorner, Martin B, Lasch, Peter, Naumann, Dieter, Dorner, Brigitte G

“…Plant and microbial toxins such as ricin, staphylococcal enterotoxin B (SEB), and the botulinum neurotoxins (BoNT) are considered as potential biological…”
Get full text

Generation and Characterization of Six Recombinant Botulinum Neurotoxins as Reference Material to Serve in an International Proficiency Test by Weisemann, Jasmin, Krez, Nadja, Fiebig, Uwe, Worbs, Sylvia, Skiba, Martin, Endermann, Tanja, Dorner, Martin B, Bergström, Tomas, Muñoz, Amalia, Zegers, Ingrid, Müller, Christian, Jenkinson, Stephen P, Avondet, Marc-Andre, Delbrassinne, Laurence, Denayer, Sarah, Zeleny, Reinhard, Schimmel, Heinz, Åstot, Crister, Dorner, Brigitte G, Rummel, Andreas

“…The detection and identification of botulinum neurotoxins (BoNT) is complex due to the existence of seven serotypes, derived mosaic toxins and more than 40…”
Get full text

De novo subtype and strain identification of botulinum neurotoxin type B through toxin proteomics by Kalb, Suzanne R., Baudys, Jakub, Rees, Jon C., Smith, Theresa J., Smith, Leonard A., Helma, Charles H., Hill, Karen, Kull, Skadi, Kirchner, Sebastian, Dorner, Martin B., Dorner, Brigitte G., Pirkle, James L., Barr, John R.

“…Botulinum neurotoxins (BoNTs) cause the disease botulism, which can be lethal if untreated. There are seven known serotypes of BoNT, A–G, defined by their…”
Get full text