Search Results - "Dormond, E"
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From the first to the third generation adenoviral vector: What parameters are governing the production yield?
Published in Biotechnology advances (01-03-2009)“…Human adenoviral viral vector serotype 5 (AdV) is presently the primary viral vector used in gene therapy trials. Advancements in AdV process development…”
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Identification of critical infection parameters to control helper-dependent adenoviral vector production
Published in Journal of biotechnology (15-06-2009)“…Helper-dependent adenoviral vectors (HDVs) are the most promising adenoviral vectors for gene therapy treatments as well as vaccination strategies. However,…”
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efficient and scalable process for helper-dependent adenoviral vector production using polyethylenimine-adenofection
Published in Biotechnology and bioengineering (15-02-2009)“…Safety requirements for adenoviral gene therapy protocols have led to the development of the third generation of vectors commonly called helper-dependent…”
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FT-IR and nuclear overhauser enhancement study of the state of urea confined in AOT-reversed micelles
Published in Colloids and surfaces. A, Physicochemical and engineering aspects (29-05-2003)“…The system urea/sodium-bis(2-ethylhexyl)sulfosuccinate (AOT) dispersed in CCl 4 and benzene-d6 was investigated by viscosimetry, FT-IR and high-resolution 1H…”
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Insights into adenoviral vector production kinetics in acoustic filter-based perfusion cultures
Published in Biotechnology and bioengineering (30-06-2004)“…One of the major limitations in the production of adenoviral vectors is the reduction in cell‐specific productivity observed for increasing cell density at…”
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Development of a suspension serum-free helper-dependent adenovirus production system and assessment of co-infection conditions
Published in Journal of virological methods (01-03-2008)“…Helper-dependent adenovirus (HDAd), deleted in all viral protein-coding sequences has been designed to reduce immune response and favor long-term expression of…”
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