Search Results - "Dorleta, Otaegui"

Acute reproductive toxicology after intratesticular injection of silver nanoparticles (AgNPs) in Wistar rats by de Brito, Juliana Lis Mendes, Lima, Vanessa Nicolau de, Ansa, Dorleta Otaegui, Moya, Sergio Enrique, Morais, Paulo Cesar, Azevedo, Ricardo Bentes de, Lucci, Carolina Madeira

“…This study aimed to evaluate the effects of an intratesticular injection of silver nanoparticles (AgNPs) on reproductive parameters and health of rats, and to…”
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In vitro and in vivo activity of a new small-molecule inhibitor of HDAC6 in mantle cell lymphoma by Pérez-Salvia, Montserrat, Aldaba, Eneko, Vara, Yosu, Fabre, Myriam, Ferrer, Cristina, Masdeu, Carme, Zubia, Aizpea, Sebastian, Eider San, Otaegui, Dorleta, Llinàs-Arias, Pere, Rosselló-Tortella, Margalida, Berdasco, Maria, Moutinho, Catia, Setien, Fernando, Villanueva, Alberto, González-Barca, Eva, Muncunill, Josep, Navarro, José-Tomás, Piris, Miguel A, Cossio, Fernando P, Esteller, Manel

“…Cancer origin and development is associated not only with genetic alterations, but also with the disturbance of epigenetic profiles.1 In this regard, the…”
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Functionalizing NaGdF4:Yb,Er Upconverting Nanoparticles with Bone-Targeting Phosphonate Ligands: Imaging and In Vivo Biodistribution by Alonso-de Castro, Silvia, Ruggiero, Emmanuel, Lekuona Fernández, Aitor, Cossío, Unai, Baz, Zuriñe, Otaegui, Dorleta, Gómez-Vallejo, Vanessa, Padro, Daniel, Llop, Jordi, Salassa, Luca

“…Lanthanide-doped upconverting nanoparticles (UCNPs) transform near infrared light (NIR) into higher-energy UV and visible light by multiphotonic processes…”
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Solvent-Free Thermal and Microwave-Assisted [3 + 2] Cycloadditions between Stabilized Azomethine Ylides and Nitrostyrenes. An Experimental and Theoretical Study by Arrieta, Ana, Otaegui, Dorleta, Zubia, Aizpea, Cossío, Fernando P, Díaz-Ortiz, Angel, de la Hoz, Antonio, Herrero, M. Antonia, Prieto, Pilar, Foces-Foces, Concepción, Pizarro, José L, Arriortua, María I

“…The stereochemical outcomes observed in the thermal and microwave-assisted [3 + 2] cycloaddition between stabilized azomethine ylides and nitrostyrenes have…”
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Development and validation of a liquid chromatography–tandem mass spectrometry for the determination of Kendine 91, a novel histone deacetylase inhibitor, in mice plasma and tissues: Application to a pharmacokinetic study by Otaegui, Dorleta, Rodríguez-Gascón, Alicia, Zubia, Aizpea, Cossío, Fernando P., Pedraz, José Luis

“…A liquid chromatography–tandem mass spectrometric method (LC–MS/MS) has been developed and validated to determine the concentration of Kendine 91 in mice…”
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Pharmacokinetics and tissue distribution of Kendine 91, a novel histone deacetylase inhibitor, in mice by Otaegui, Dorleta, Rodríguez-Gascón, Alicia, Zubia, Aizpea, Cossío, Fernando P, Pedraz, José Luis

“…Purpose The present investigation was undertaken to characterize the pharmacokinetics and oral bioavailability of Kendine 91 in mice and to compare it with…”
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Rational Design and Experimental Analysis of Short-Oligonucleotide Substrate Specificity for Targeting Bacterial Nucleases by Jiménez, Tania, Botero, Juliana, Otaegui, Dorleta, Calvo, Javier, Hernandez, Frank J, San Sebastian, Eider

“…An undecamer oligonucleotide probe based on a pair of deoxythymidines flanked by several modified nucleotides is a specific and highly efficient biosensor for…”
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Ultrasmall Manganese Ferrites for In Vivo Catalase Mimicking Activity and Multimodal Bioimaging by Carregal‐Romero, Susana, Miguel‐Coello, Ana Beatriz, Martínez‐Parra, Lydia, Martí‐Mateo, Yolanda, Hernansanz‐Agustín, Pablo, Fernández‐Afonso, Yilian, Plaza‐García, Sandra, Gutiérrez, Lucía, Muñoz‐Hernández, María del Mar, Carrillo‐Romero, Juliana, Piñol‐Cancer, Marina, Lecante, Pierre, Blasco‐Iturri, Zuriñe, Fadón, Lucía, Almansa‐García, Ana C., Möller, Marco, Otaegui, Dorleta, Enríquez, Jose Antonio, Groult, Hugo, Ruíz‐Cabello, Jesús

“…Manganese ferrite nanoparticles display interesting features in bioimaging and catalytic therapies. They have been recently used in theranostics as contrast…”
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Abstract 4725: Efficacy of a new small-molecule inhibitor of histone deacetylase 6 (HDAC6) in preclinical models of B-cell lymphoma and acute myeloid leukemia by Villanueva, Lorea, Perez-Salvia, Montserrat, Aldaba, Eneko, Vara, Yosu, Fabre, Myriam, Ferrer, Cristina, Masdeu, Carme, Zubia, Aizpea, Sebastian, Eider San, Otaegui, Dorleta, Llinàs-Arias, Pere, Rosselló-Tortella, Margalida, Berdasco, María, Setien, Fernando, Moutinho, Catia, Villanueva, Alberto, González-Barca, Eva, Muncunill, Josep, Navarro, José Tomás, Piris, Miguel Ángel, Cossio, Fernando, Esteller, Manel

“…Histone deacetylase 6 (HDAC6) is a protein modifier that is an increasingly attractive pharmacological target. Interestingly, the observation that the HDAC6…”
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Efficacy of a New Small-Molecule Inhibitor of Histone Deacetylase 6 (HDAC6) in Preclinical Models of B-Cell Lymphoma and Acute Myeloid Leukemia by Perez-Salvia, Montserrat, Eneko, Aldaba, Yosu, Vara, Myriam, Fabre, Cristina, Ferrer, Carme, Masdeu, Aizpea, Zubia, Eider, San Sebastian, Dorleta, Otaegui, Pere, Llinàs-Arias, Margalida, Rosselló-Tortella, Maria, Berdasco, Fernando, Setien, Catia, Moutinho, Alberto, Villanueva, González-Barca, Eva, Muncunill, Josep, Navarro, Jose Tomas, Piris, Miguel Angel, Fernando, Cossio, Esteller, Manel

“…Histone deacetylase 6 (HDAC6) is a protein modifier that is an increasingly attractive pharmacological target. Interestingly, the observation that the HDAC6…”
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In vitro and in vivo activity of a new small-molecule inhibitor of HDAC6 in mantle cell lymphoma by Pérez Salvia, Montserrat, Aldaba, Eneko, Vara, Yosu, Fabre, Myriam, Ferrer, Cristina, Masdeu, Carme, Zubia, Aizpea, San Sebastian, Eider, Otaegui, Dorleta, Llinàs-Arias, Pere, Rosselló-Tortella, Margalida, Berdasco, María, Moutinho, Cátia, Setién, Fernando, Villanueva Garatachea, Alberto, González Barca, Eva, Muncunill, Josep, Navarro, José-Tomás, Piris, Miguel A, Cossio, Fernando P, Esteller, Manel

“…Cancer origin and development is associated not only with genetic alterations, but also with the disturbance of epigenetic profiles.1 In this regard, the…”
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Development and validation of a LC-MS assay for the quantification of ikh12 a novel anti-tumor candidate in rat plasma and tissues and its application in a pharmacokinetic study by Otaegui, Dorleta, Masdeu, Carme, Aldaba, Eneko, Vara, Yosu, Zubia, Aizpea, San Sebastian, Eider, Alcalá, Maria, Villafruela, Sergio, Cossío, Fernando P., Rodriguez-Gascón, Alicia

“…IKH12 is a novel histone deacetylase 6 selective inhibitor. A rapid and sensitive liquid chromatography tandem mass spectrometry method was developed and…”
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