Search Results - "Dorkoosh, F A"
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Shelf life and delivery enhancement of vitamin C using chitosan nanoparticles
Published in Food chemistry (01-06-2011)“…► Reaction of chitosan with sodium tripolyphosphate to prepare chitosan nanoparticles. ► Characterisation of the nanoparticles (Zeta potential, particle size…”
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Chitosan nanoparticle to carry vitamin C through the gastrointestinal tract and induce the non-specific immunity system of rainbow trout (Oncorhynchus mykiss)
Published in Carbohydrate polymers (01-08-2011)“…► Chitosan nanoparticle has shown spherical shape and smooth surface. ► Chitosan nanoparticle could protect vitamin C through the gastrointestinal tract of…”
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Preparation, characterization and antibacterial activities of chitosan, N-trimethyl chitosan (TMC) and N-diethylmethyl chitosan (DEMC) nanoparticles loaded with insulin using both the ionotropic gelation and polyelectrolyte complexation methods
Published in International journal of pharmaceutics (01-05-2008)“…TMC and DEMC, quaternized derivatives of chitosan, have been shown to have penetration enhancement properties and able to open the tight junctions of the…”
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Permeation enhancer effect of chitosan and chitosan derivatives: Comparison of formulations as soluble polymers and nanoparticulate systems on insulin absorption in Caco-2 cells
Published in European journal of pharmaceutics and biopharmaceutics (01-09-2008)“…In this study four quaternized derivatives of chitosan: trimethyl chitosan (TMC), dimethylethyl chitosan (DMEC), diethylmethyl chitosan (DEMC) and triethyl…”
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Preparation and evaluation of chitosan–DNA–FAP-B nanoparticles as a novel non-viral vector for gene delivery to the lung epithelial cells
Published in International journal of pharmaceutics (16-05-2011)“…In vitro transfection efficiency. (A) Naked DNA, (B) chitosan–DNA nanoparticles, (C) chitosan–DNA–FAP-B nanoparticles (chitosan/FAP-B = 1/0.5), (D)…”
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In vivo transfection study of chitosan-DNA-FAP-B nanoparticles as a new non viral vector for gene delivery to the lung
Published in International journal of pharmaceutics (12-12-2011)“…Lucifrase gene expression in mice lungs after nanoparticles nebulization. Gene therapy targeted at the respiratory epithelium holds therapeutic potential for…”
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Intestinal absorption of human insulin in pigs using delivery systems based on superporous hydrogel polymers
Published in International journal of pharmaceutics (24-10-2002)“…In this in vivo study, novel delivery systems based on superporous hydrogel (SPH) and SPH composite (SPHC) polymers were used to improve the intestinal…”
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Feasibility study on the retention of superporous hydrogel composite polymer in the intestinal tract of man using scintigraphy
Published in Journal of controlled release (30-09-2004)“…In recent years, many complex oral drug delivery systems have been developed using various polymers in order to achieve better drug targeting and drug…”
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Preparation and NMR characterization of superporous hydrogels (SPH) and SPH composites
Published in Polymer (Guilford) (01-11-2000)“…In this investigation the mechanism of synthesis and characterization of Superporous Hydrogel (SPH) and SPH composites were studied. Solid-state 13C NMR was…”
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Evaluation and optimization of chitosan derivatives-based gene delivery system via kidney epithelial cells
Published in Advanced pharmaceutical bulletin (2012)“…Purpose: Non-viral vectors have been widely proposed as safer alternatives to viral vectors, and cationic polymers have gained increasing attention because…”
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Application of artificial neural networks for optimization of preparation of insulin nanoparticles composed of quaternized aromatic derivatives of chitosan
Published in Drug research (Stuttgart) (01-03-2014)“…The aim of this research was to develop an artificial neural network (ANN) in order to design a nanoparticulate oral drug delivery system for insulin. The pH…”
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Enhancement and Characterization of Chitosan Extraction from the Wastes of Shrimp Packaging Plants
Published in Journal of polymers and the environment (01-09-2011)“…Chitin is the second most abundant carbohydrate polymer in nature next to cellulose. The main source of chitin is crustacean shells. Chitosan, derived from…”
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A Novel Nanoemulsion-Based Method to Produce Ultrasmall, Water-Dispersible Nanoparticles from Chitosan, Surface Modified with Cell-Penetrating Peptide for Oral Delivery of Proteins and Peptides [Retraction]
Published in International journal of nanomedicine (01-01-2022)“…[This retracts the article DOI: 10.2147/IJN.S116063.]…”
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Mathematical modelling of the transport of hydroxypropyl-β-cyclodextrin inclusion complexes of ranitidine hydrochloride and furosemide loaded chitosan nanoparticles across a Caco-2 cell monolayer
Published in International journal of pharmaceutics (17-01-2012)“…Chitosan nanoparticles (CS-NPs) have been used to enhance the permeability of furosemide and ranitidine hydrochloride (ranitidine HCl) which were selected as…”
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N-Diethylmethyl chitosan for gene delivery to pancreatic cancer cells and the relation between charge ratio and biologic properties of polyplexes via interpolations polynomial
Published in International journal of pharmaceutics (28-11-2011)“…In gene therapy of pancreatic cancer, non-viral vectors show an important role. These vectors are modified with the aim of improvement for pancreatic cancer…”
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Preparation, Design for Optimization and in Vitro Evaluation of Insulin Nanoparticles Integrating Thiolated Chitosan Derivatives
Published in Journal of drug delivery science and technology (01-01-2014)“…This study aims at the statistical optimization and in vitro characterization of insulin nanoparticles containing thiolatd N-diethyl methyl chitosan (DEMC-Cys)…”
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Development and characterization of a novel peroral peptide drug delivery system
Published in Journal of controlled release (28-04-2001)“…Novel drug delivery systems were developed for peroral administration of peptide and protein drugs for site specific mechanical fixation at the gut wall and…”
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Effect of Zeolite Nano-Materials and Artichoke (Cynara scolymus L.) Leaf Extract on Increase in Urinary Clearance of Systematically Absorbed Nicotine
Published in Arzneimittel-Forschung (01-12-2012)“…Nicotine, the main pharmacologically active component in tobacco and cigarette, has some toxic effects and also high potential for addiction. In this study,…”
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Evaluation of superporous hydrogel (SPH) and SPH composite in porcine intestine ex-vivo: assessment of drug transport, morphology effect, and mechanical fixation to intestinal wall
Published in European journal of pharmaceutics and biopharmaceutics (01-03-2002)“…The objective of this study was to investigate the potential of superporous hydrogel (SPH) and SPH composite (SPHC) polymers to enhance the transport of…”
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Development and Validation of Rapid Stability-Indicating RP-HPLC-DAD Method for the Quantification of Lapatinib and Mass Spectrometry Analysis of Degraded Products
Published in Journal of chromatographic science (01-07-2015)“…A rapid, simple and stability-indicating high-performance liquid chromatography assay method was developed and validated for quantitative analysis of lapatinib…”
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