Search Results - "Dorgan, D."

Inhaled mRNA therapy for treatment of cystic fibrosis: Interim results of a randomized, double‐blind, placebo‐controlled phase 1/2 clinical study by Rowe, S.M., Zuckerman, J.B., Dorgan, D., Lascano, J., McCoy, K., Jain, M., Schechter, M.S., Lommatzsch, S., Indihar, V., Lechtzin, N., McBennett, K., Callison, C., Brown, C., Liou, T.G., MacDonald, K.D., Nasr, S.Z., Bodie, S., Vaughn, M., Meltzer, E.B., Barbier, A.J.

“…•CFTR mRNA was delivered by aerosol in lipid nanoparticles to cystic fibrosis adults.•In this small first-in-human study treatment was generally safe and well…”
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185 Use of the hemoglobin A1c test as a screening tool for cystic fibrosis related diabetes by Nicolo, M, Dorgan, D, Ferrin, M, Holsclaw, D, Smith, S, Hadjiliadis, D

“…Objective To determine the optimal hemoglobin A1c (HgbA1c) level to screen for Cystic Fibrosis Related Diabetes (CFRD) in a population of adults with cystic…”
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WS02.3 Randomized, double-blind (DB), placebo-controlled study and open-label (OL) extension of liposomal amikacin for inhalation (LAI) in patients with refractory nontuberculous mycobacterial (NTM) lung disease (LD) by Olivier, K.N, Eagle, G, McGinnis, J.P, Micioni, L, Daley, C.L, Winthrop, K.L, Ruoss, S, Addrizzo-Harris, D.J, Flume, P, Dorgan, D, Salathe, M, Brown-Elliott, B.A, Wallace, R, Griffith, D.E

“…Objective NTM-LD management often requires lengthy multidrug antibiotic regimens (MDARs) and can be complicated by drug toxicity and poor prognosis. Efficacy,…”
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WS19.1 Using microsystems methods to improve nutritional outcomes in an adult CF center: a quality improvement (QI) initiative by Ferrin, M, Nicolo, M, Dorgan, D, Hadjiliadis, D, Holsclaw, D, Shechtman, M, Kreider, P, Robinson, C.B

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Geriatric cystic fibrosis: clinical features of patients over 50 years of age by Hadjiliadis, D, Kaplan, M, Ferrin, M, Imbesi, G, Dorgan, D, Holsclaw, D

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132 Current trends in sputum expectoration and respiratory sampling for research: A single-center experience by Hong, G., O’Dea, A., Borowiec, A., Sheikh, S., Dorgan, D., Hadjiliadis, D.

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406: Impact of highly-effective CFTR modulation on the microbial environment in cystic fibrosis by Hong, G., Lipscombe, C., Daniel, S., O’Dea, A., Bittinger, K., Dorgan, D., Hadjiliadis, D.

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Evans−Tishchenko Coupling of Heteroaryl Aldehydes by Dorgan, Philip D, Durrani, Jamie, Cases-Thomas, Manuel J, Hulme, Alison N

“…The low-temperature Evans−Tishchenko coupling of a range of functionalized heteroaryl aldehydes with β-hydroxy ketones in the presence of a Sm(III) catalyst…”
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WS05.06 Phase 1/2a randomized, double-blind, placebo-controlled study: safety, Pk, and Efficacy outcome measures of inhaled Gallium Citrate (AR-501) in P Aeruginosa infected Cystic Fibrosis patients by Cohen, A., Lechtzin, N., Boas, S., Pena, T., McBennett, K., Gross, J., Dorgan, D., Couch, L., Hoffman, L., Saavedra, M., Hisert, K., Stevens-Brogan, M., Plascencia, C., Deans, L., Kelson, A., Lovalenti, P., Woo, J., Truong, V., Jafri, H.S.

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544: Safety and tolerability of single and repeat doses of MRT5005, an inhaled CFTR mRNA replacement therapy, in adult CF patients by Rowe, S., Dorgan, D., Lascano, J., Zuckerman, J., McCoy, K., Jain, M., Schechter, M., Lommatzsch, S., Indihar, V., Lechtzin, N., McBennett, K., Callison, J., Brown, C., Liou, T., MacDonald, K., Nasr, S., Bodie, S., Meltzer, E., Barbier, A.

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D108 DIAGNOSIS AND MANAGEMENT OF NONTUBERCULOUS MYCOBACTERIA INFECTIONS: Subgroup Analyses Of Baseline Demographics And Efficacy In Patients With Refractory Nontuberculous Mycobacteria (ntm) Lung Infection Treated With Liposomal Amikacin For Inhalation (lai) by Winthrop, K L, Eagle, G, McGinnis, J P, Micioni, L, Daley, C L, Ruoss, S J, Addrizzo-Harris, D J, Flume, P A, Dorgan, D J, Salathe, M, Brown-Elliott, B A, Wallace, R J, Griffith, D E, Olivier, K N

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D108 DIAGNOSIS AND MANAGEMENT OF NONTUBERCULOUS MYCOBACTERIA INFECTIONS: Analysis Of Functional Exercise Capacity (via The Six-Minute Walk Test [6mwt]) And Culture Negativity In Patients With Nontuberculous Mycobacteria (ntm) Lung Infection Refractory To Guideline-Based Therapy Treated With Liposomal Amikacin For Inhalation (lai) by Ruoss, S J, Eagle, G, McGinnis, J P, Micioni, L, Daley, C L, Winthrop, K L, Addrizzo-Harris, D J, Flume, P A, Dorgan, D J, Salathe, M, Griffith, D E, Olivier, K N

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B103 FIXING A HOLE: ADVANCES IN DIAGNOSTIC AND THERAPEUTIC BRONCHOSCOPY: Management Of Airway Complications Following Lung Transplantation by Frye, L K, Pena, T, Ahya, V N, Lee, J, Shah, R J, Dorgan, D, Christie, J D, Hadjiliadis, D, Haas, A, Sterman, D H, Moon, E K, Bessich, J L, Cantu, E, Diamond, J, Lanfranco, A

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C27 DIAGNOSIS AND TREATMENT OF NONTUBERCULOUS MYCOBACTERIA INFECTIONS: A Randomized, Double-Blind, Placebo-Controlled Study Of Liposomal Amikacin For Inhalation (arikace®) In Patients With Recalcitrant Nontuberculous Mycobacterial Lung Disease by Olivier, K N, Gupta, R, Daley, C L, Winthrop, K L, Ruoss, S, Addrizzo-Harris, D J, Flume, P, Dorgan, D, Salathe, M A, Brown-Elliott, B A, Wallace, R J, Griffith, D E

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D108 DIAGNOSIS AND MANAGEMENT OF NONTUBERCULOUS MYCOBACTERIA INFECTIONS: Efficacy Of Liposomal Amikacin For Inhalation (lai) In Achieving Nontuberculous Mycobacteria (ntm) Culture Negativity In Patients Whose Lung Infection Is Refractory To Guideline-Based Therapy by Biller, J A, Eagle, G, McGinnis, J P, Micioni, L, Daley, C L, Winthrop, K L, Ruoss, S J, Addrizzo-Harris, D J, Flume, P A, Dorgan, D J, Salathe, M, Brown-Elliott, B A, Wallace, R J, Griffith, D E, Olivier, K N

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Good health! - But only for a few by Dorgan, D

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L-carnitine: therapeutic strategy for metabolic encephalopathy by Kim, C S, Dorgan, D R, Roe, C R

“…The organic anion transport system in the choroid plexus is responsible for excretion of organic anions from brain to plasma. Disruption of this system could…”
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Phenytoin (dilantin)-induced cleft lip and palate in A/J mice: a scanning and transmission electron microscopic study by Sulik, K K, Johnston, M C, Ambrose, L J, Dorgan, D

“…High incidences of cleft lip and palate (CLP) produced by maternal intraperitoneal administration of 75 mg/kg phenytoin on gestational day 10 to A/J mice are…”
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Evaas-Tishchenko Coupling of Heteroaryl Aldehydes by DORGAN, Philip D, DURRANI, Jamie, CASES-THOMAS, Manuel J, HULME, Alison N

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An evans-tishchenko/ring-closing alkyne metathesis approach towards the synthesis of disorazole c by Dorgan, Philip D

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