Search Results - "Dorfman, Jeffrey R"

Detectable HIV-1 in semen in individuals with very low blood viral loads by Kariuki, Samuel Mundia, Selhorst, Philippe, Norman, Jennifer, Cohen, Karen, Rebe, Kevin, Williamson, Carolyn, Dorfman, Jeffrey R

“…Several reports indicate that a portion (5-10%) of men living with HIV-1 intermittently shed HIV-1 RNA into seminal plasma while on long term effective…”
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Incidence and risk factors for neonatal tetanus in admissions to Kilifi County Hospital, Kenya by Ibinda, Fredrick, Bauni, Evasius, Kariuki, Symon M, Fegan, Greg, Lewa, Joy, Mwikamba, Monica, Boga, Mwanamvua, Odhiambo, Rachael, Mwagandi, Kiponda, Seale, Anna C, Berkley, James A, Dorfman, Jeffrey R, Newton, Charles R J C

“…Neonatal Tetanus (NT) is a preventable cause of mortality and neurological sequelae that occurs at higher incidence in resource-poor countries, presumably…”
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Turnover and Proliferation of NK Cells in Steady State and Lymphopenic Conditions by Jamieson, Amanda M, Isnard, Patricia, Dorfman, Jeffrey R, Coles, Mark C, Raulet, David H

“…To gain insight into NK cell dynamics, we investigated the turnover and proliferation rates of NK cells in normal and lymphopenic conditions. In contrast to…”
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Iron Deficiency and Malaria among Children Living on the Coast of Kenya by Nyakeriga, Alice M., Troye-Blomberg, Marita, Dorfman, Jeffrey R., Alexander, Neal D., Bäck, Rune, Kortok, Moses, Chemtai, Alex K., Marsh, Kevin, Williams, Thomas N.

“…Both iron deficiency and malaria are common in much of sub-Saharan Africa, and the interaction between these conditions is complex. To investigate the…”
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Refined Identification of Neutralization-Resistant HIV-1 CRF02_AG Viruses by ABRAHAM JACOB, Rajesh, ABRAHAMS, Fatima, TONGO, Marcel, SCHOMAKER, Michael, ROUX, Paul, MPOUDI NGOLE, Eitel, BURGERS, Wendy A, DORFMAN, Jeffrey R

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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B Cell Memory to 3 Plasmodium falciparum Blood-Stage Antigens in a Malaria-Endemic Area by Dorfman, Jeffrey R., Bejon, Philip, Ndungu, Francis M., Langhorne, Jean, Kortok, Moses Mosobo, Lowe, Brett S., Mwangi, Tabitha W., Williams, Thomas N., Marsh, Kevin

“…To gain insight into why antibody responses to malarial antigens tend to be short lived, we studied antigenspecific memory B cells from donors in an area where…”
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High Degree of HIV-1 Group M (HIV-1M) Genetic Diversity within Circulating Recombinant Forms: Insight into the Early Events of HIV-1M Evolution by Tongo, Marcel, Dorfman, Jeffrey R, Martin, Darren P

“…The existence of various highly divergent HIV-1 lineages and of recombination-derived sequence tracts of indeterminate origin within established circulating…”
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Analysis of serum microRNA‐122 in a randomized controlled trial of N‐acetylcysteine for treatment of antituberculosis drug‐induced liver injury by Moosa, Muhammed Shiraz, Russomanno, Giusy, Dorfman, Jeffrey R., Gunter, Hannah, Patel, Chandni, Costello, Eithne, Carr, Dan, Maartens, Gary, Pirmohamed, Munir, Goldring, Christopher, Cohen, Karen

“…Aim Serum microRNA‐122 (miR‐122) is a novel biomarker for drug‐induced liver injury, with good sensitivity in the early diagnosis of paracetamol‐induced liver…”
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VAR2CSA Domains Expressed in Escherichia coli Induce Cross-Reactive Antibodies to Native Protein by Oleinikov, Andrew V., Francis, Susan E., Dorfman, Jeffrey R., Rossnagle, Eddie, Balcaitis, Stephanie, Getz, Tony, Avril, Marion, Gose, Severin, Smith, Joseph D., Fried, Michal, Duffy, Patrick E.

“…The variant surface antigen VAR2CSA is a pregnancy malaria vaccine candidate, but its size and polymorphism are obstacles to development. We expressed 3D7-type…”
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Neutralization sensitivity of genital tract HIV-1: shift in selective milieu shapes the population available to transmit by Kariuki, Samuel Mundia, Selhorst, Philippe, Abrahams, Melissa-Rose, Rebe, Kevin, Williamson, Carolyn, Dorfman, Jeffrey R.

“…Previous studies indicate that transmitted/founder HIV-1 isolates are sensitive to neutralization by the transmitting donor's antibodies. This is true in at…”
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The comparative inhibitory potency of salivary mucins against human immunodeficiency virus type 1 by McQuaid, Isla K., Dorfman, Jeffrey R., Mall, Anwar S.

“…MUC5B and MUC7 salivary mucins are reported to inhibit HIV-1 entry into target cells in vitro; however, their relative inhibitory potencies have not been…”
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In Utero Human Cytomegalovirus Infection Is Associated With Increased Levels of Putatively Protective Maternal Antibodies in Nonprimary Infection: Evidence for Boosting but Not Protection by Dorfman, Jeffrey R, Balla, Sashkia R, Pathirana, Jayani, Groome, Michelle J, Madhi, Shabir A, Moore, Penny L

“…Abstract Background Although primary maternal cytomegalovirus infections are associated with higher risk of in utero transmission, most fetal infections…”
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Variability and Robustness in T Cell Activation from Regulated Heterogeneity in Protein Levels by Feinerman, Ofer, Veiga, Joël, Dorfman, Jeffrey R, Germain, Ronald N, Altan-Bonnet, Grégoire

“…In T cells, the stochasticity of protein expression could contribute to the useful diversification of biological functions within a clonal population or…”
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The HIV-1 transmission bottleneck by Kariuki, Samuel Mundia, Selhorst, Philippe, Ariën, Kevin K, Dorfman, Jeffrey R

“…It is well established that most new systemic infections of HIV-1 can be traced back to one or a limited number of founder viruses. Usually, these founders are…”
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Immunogenicity of a single-dose compared with a two-dose primary series followed by a booster dose of ten-valent or 13-valent pneumococcal conjugate vaccine in South African children: an open-label, randomised, non-inferiority trial by Madhi, Shabir A, Mutsaerts, Eleonora AML, Izu, Alane, Boyce, Welekazi, Bhikha, Sutika, Ikulinda, Benit T, Jose, Lisa, Koen, Anthonet, Nana, Amit J, Moultrie, Andrew, Roalfe, Lucy, Hunt, Adam, Goldblatt, David, Cutland, Clare L, Dorfman, Jeffrey R

“…Routine childhood immunisation with pneumococcal conjugate vaccine (PCV) has changed the epidemiology of pneumococcal disease across age groups, providing an…”
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Compartmentalization and Clonal Amplification of HIV-1 in the Male Genital Tract Characterized Using Next-Generation Sequencing by Kariuki, Samuel Mundia, Selhorst, Philippe, Anthony, Colin, Matten, David, Abrahams, Melissa-Rose, Martin, Darren P, Ariën, Kevin K, Rebe, Kevin, Williamson, Carolyn, Dorfman, Jeffrey R

“…Compartmentalization of HIV-1 between the systemic circulation and the male genital tract may have a substantial impact on which viruses are available for…”
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HIV drug resistance in various body compartments by van Zyl, Gert U., Dorfman, Jeffrey R., Kearney, Mary F.

“…Purpose of review HIV drug resistance testing using blood plasma or dried blood spots forms part of international guidelines. However, as the clinical utility…”
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Anti-V3/Glycan and Anti-MPER Neutralizing Antibodies, but Not Anti-V2/Glycan Site Antibodies, Are Strongly Associated with Greater Anti-HIV-1 Neutralization Breadth and Potency by Jacob, Rajesh Abraham, Moyo, Thandeka, Schomaker, Michael, Abrahams, Fatima, Grau Pujol, Berta, Dorfman, Jeffrey R

“…The membrane-proximal external region (MPER), the V2/glycan site (initially defined by PG9 and PG16 antibodies), and the V3/glycans (initially defined by…”
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Elucidation of Early Evolution of HIV-1 Group M in the Congo Basin Using Computational Methods by Tongo, Marcel, Martin, Darren P, Dorfman, Jeffrey R

“…The Congo Basin region is believed to be the site of the cross-species transmission event that yielded HIV-1 group M (HIV-1M). It is thus likely that the virus…”
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Molecular Basis of Unusually High Neutralization Resistance in Tier 3 HIV-1 Strain 253-11 by Moyo, Thandeka, Ereño-Orbea, June, Jacob, Rajesh Abraham, Pavillet, Clara E, Kariuki, Samuel Mundia, Tangie, Emily N, Julien, Jean-Philippe, Dorfman, Jeffrey R

“…Understanding the mechanisms used by HIV-1 to evade antibody neutralization may contribute to the design of a high-coverage vaccine. The tier 3 virus 253-11 is…”
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