Search Results - "Dorahy, Douglas J."

Lumacaftor/ Ivacaftor improves exercise tolerance in patients with Cystic Fibrosis and severe airflow obstruction by Wark, Peter A B, Cookson, Kim, Thiruchelvam, Theeba, Brannan, John, Dorahy, Douglas J

“…Treatment of patients with Cystic Fibrosis homozygous for the Phe508del gene, with Lumacaftor /Ivacaftor (LUM/IVA) improves outcomes in patients with FEV1 >…”
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Re: Complex Regional Pain Syndrome After Infliximab Infusion by Russo, Marc A., MBBS, FANZCA, FFPMANZCA, Dorahy, Douglas J., PhD

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A randomised trial of hypertonic saline during hospitalisation for exacerbation of cystic fibrosis by Dentice, Ruth L, Elkins, Mark R, Middleton, Peter G, Bishop, Jennifer R, Wark, Peter A B, Dorahy, Douglas J, Harmer, Christopher J, Hu, Honghua, Bye, Peter T P

“…The mucoactive effects of hypertonic saline should promote exacerbation resolution in people with cystic fibrosis (CF). To determine the effects of hypertonic…”
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Biochemical isolation of a membrane microdomain from resting platelets highly enriched in the plasma membrane glycoprotein CD36 by Dorahy, D J, Lincz, L F, Meldrum, C J, Burns, G F

“…Here we describe the isolation and characterization of a Triton X-100-insoluble fraction isolated from lysates of platelets by flotation in sucrose gradients…”
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Direct integrin αvβ6-ERK binding: implications for tumour growth by AHMED, Nuzhat, JUN NIU, DORAHY, Douglas J, XINHUA GU, ANDREWS, Sarah, MELDRUM, Cliff J, SCOTT, Rodney J, BAKER, Mark S, MACREADIE, Ian G, AGREZ, Michael V

“…Blockade of the mitogen-activated protein (MAP) kinase pathway suppresses growth of colon cancer in vivo. Here we demonstrate a direct link between the…”
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Integrin expression in colon cancer cells is regulated by the cytoplasmic domain of the β6 integrin subunit by Niu, Jun, Dorahy, Douglas J., Gu, Xinhua, Scott, R.J., Draganic, Brian, Ahmed, Nuzhat, Agrez, Michael V.

“…We have previously reported that the αvβ6 integrin upregulates its own expression in a protein kinase C‐dependent manner with increasing cell density. The…”
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Active Lyn protein tyrosine kinase is selectively enriched within membrane microdomains of resting platelets by Dorahy, D J, Burns, G F

“…Circulating platelets are primed to respond very rapidly to thrombogenic stimuli, but most platelets complete their lifespan without ever becoming activated…”
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Stimulation of Platelet Activation and Aggregation by a Carboxyl-terminal Peptide from Thrombospondin Binding to the Integrin-associated Protein Receptor by Dorahy, D J, Thorne, R F, Fecondo, J V, Burns, G F

“…Thrombospondin, a major secretory product of the α-granules of activated platelets, is a large trimeric glycoprotein that plays an important role in platelet…”
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TLiSA1 (PTA1) Activation Antigen Implicated in T Cell Differentiation and Platelet Activation Is a Member of the Immunoglobulin Superfamily Exhibiting Distinctive Regulation of Expression by Sherrington, Paul D., Scott, Judith L., Jin, Boquan, Simmons, David, Dorahy, Douglas J., Lloyd, Jennifer, Brien, Joan H., Aebersold, Ruedi H., Adamson, Janet, Zuzel, Mirko, Burns, Gordon F.

“…T lineage-specific activation antigen 1 (TLiSA1) antigen was initially described as a T lineage-specific activation antigen involved in the differentiation of…”
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Cytoplasmic interactions between decay-accelerating factor and intercellular adhesion molecule-1 are not required for coxsackievirus A21 cell infection by Shafren, Darren R, Dorahy, Douglas J, Thorne, Rick F, Barry, Richard D

“…Picornaviral Research Unit, Discipline of Immunology and Microbiology and 2 Cancer Research Unit, Faculty of Medicine and Health Sciences, The University of…”
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Antibody Binding to Individual Short Consensus Repeats of Decay-Accelerating Factor Enhances Enterovirus Cell Attachment and Infectivity by Shafren, Darren R, Dorahy, Douglas J, Thorne, Rick F, Kinoshita, Taroh, Barry, Richard D, Burns, Gordon F

“…Decay-accelerating factor (DAF), a widely expressed membrane complement-regulatory protein, is utilized as a cellular receptor by many human enteric pathogens…”
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Coxsackievirus A21 binds to decay-accelerating factor but requires intercellular adhesion molecule 1 for cell entry by Shafren, D R, Dorahy, D J, Ingham, R A, Burns, G F, Barry, R D

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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CD36 Is a Ditopic Glycoprotein with the N-Terminal Domain Implicated in Intracellular Transport by Gruarin, Paola, Thorne, Rick F., Dorahy, Douglas J., Burns, Gordon F., Sitia, Roberto, Alessio, Massimo

“…The CD36 receptor sequence predicts two hydrophobic domains located at the N- and C-termini of the protein, but there are conflicting reports as to whether the…”
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Integrin expression in colon cancer cells is regulated by the cytoplasmic domain of the beta6 integrin subunit by Niu, Jun, Dorahy, Douglas J, Gu, Xinhua, Scott, R J, Draganic, Brian, Ahmed, Nuzhat, Agrez, Michael V

“…We have previously reported that the alphavbeta6 integrin upregulates its own expression in a protein kinase C-dependent manner with increasing cell density…”
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Mouse cells expressing human intercellular adhesion molecule-1 are susceptible to infection by coxsackievirus A21 by Shafren, D R, Dorahy, D J, Greive, S J, Burns, G F, Barry, R D

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Direct integrin alphavbeta6-ERK binding: implications for tumour growth by Ahmed, Nuzhat, Niu, Jun, Dorahy, Douglas J, Gu, Xinhua, Andrews, Sarah, Meldrum, Cliff J, Scott, Rodney J, Baker, Mark S, Macreadie, Ian G, Agrez, Michael V

“…Blockade of the mitogen-activated protein (MAP) kinase pathway suppresses growth of colon cancer in vivo. Here we demonstrate a direct link between the…”
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Direct integrin [alpha]v[beta]6-ERK binding: implications for tumour growth by Ahmed, Nuzhat, Niu, Jun, Dorahy, Douglas J, Gu, Xinhua, Andrews, Sarah, Meldrum, Cliff J, Scott, Rodney J, Baker, Mark S, Macreadie, Ian G, Agrez, Michael V

“…Blockade of the mitogen-activated protein (MAP) kinase pathway suppresses growth of colon cancer in vivo. Here we demonstrate a direct link between the…”
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CD36 Forms Covalently Associated Dimers and Multimers in Platelets and Transfected COS-7 Cells by Thorne, Rick F., Meldrum, Clifford J., Harris, Simon J., Dorahy, Douglas J., Shafren, Darren R., Berndt, Michael C., Burns, Gordon F., Gibson, Peter G.

“…CD36 is a transmembrane glycoprotein expressed on the surface of a number of cell types. The analysis of CD36 from platelets using immunoblotting, gel…”
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CD36 Is Spatially Associated with Glycoprotein IIb-IIIa (αIIbβ3) on the Surface of Resting Platelets by Dorahy, Douglas J., Berndt, Michael C., Shafren, Darren R., Burns, Gordon F.

“…Platelet activation and aggregation induced by agonists such as thrombin are accompanied by the phosphorylation of several proteins on tyrosine. Such tyrosine…”
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