Search Results - "Dopazo, Ana"
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Trained immunity induction by the inactivated mucosal vaccine MV130 protects against experimental viral respiratory infections
Published in Cell reports (Cambridge) (04-01-2022)“…MV130 is an inactivated polybacterial mucosal vaccine that confers protection to patients against recurrent respiratory infections, including those of viral…”
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2
Cux1 and Cux2 Regulate Dendritic Branching, Spine Morphology, and Synapses of the Upper Layer Neurons of the Cortex
Published in Neuron (Cambridge, Mass.) (27-05-2010)“…Dendrite branching and spine formation determines the function of morphologically distinct and specialized neuronal subclasses. However, little is known about…”
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3
The G4 resolvase Dhx36 modulates cardiomyocyte differentiation and ventricular conduction system development
Published in Nature communications (04-10-2024)“…Extensive genetic studies have elucidated cardiomyocyte differentiation and associated gene networks using single-cell RNA-seq, yet the intricate…”
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4
Retraction Note: TRIB2 confers resistance to anti-cancer therapy by activating the serine/threonine protein kinase AKT
Published in Nature communications (19-07-2023)Get full text
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5
Endogenous IL-1 receptor antagonist restricts healthy and malignant myeloproliferation
Published in Nature communications (03-01-2023)“…Here we explored the role of interleukin-1β (IL-1β) repressor cytokine, IL-1 receptor antagonist (IL-1rn), in both healthy and abnormal hematopoiesis. Low…”
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BCG priming followed by a novel interleukin combination activates Natural Killer cells to selectively proliferate and become anti-tumour long-lived effectors
Published in Scientific reports (07-06-2024)“…The short-lived nature and heterogeneity of Natural Killer (NK) cells limit the development of NK cell-based therapies, despite their proven safety and…”
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Author Correction: Endogenous IL-1 receptor antagonist restricts healthy and malignant myeloproliferation
Published in Nature communications (30-06-2023)Get full text
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8
NGFR regulates stromal cell activation in germinal centers
Published in Cell reports (Cambridge) (27-02-2024)“…Nerve growth factor receptor (NGFR) is expressed by follicular dendritic cells (FDCs). However, the role of NGFR in the humoral response is not well defined…”
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Spatial and temporal gene expression differences in core and periinfarct areas in experimental stroke: a microarray analysis
Published in PloS one (17-12-2012)“…A large number of genes are regulated to promote brain repair following stroke. The thorough analysis of this process can help identify new markers and develop…”
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AG-NGS: A powerful and user-friendly computing application for the semi-automated preparation of next-generation sequencing libraries using open liquid handling platforms
Published in BioTechniques (01-01-2017)“…Protocol Summary We have developed automatic genomics NGS (AG-NGS), a computing application that allows an open liquid handling platform to be transformed into…”
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Mutant PRPF8 Causes Widespread Splicing Changes in Spliceosome Components in Retinitis Pigmentosa Patient iPSC-Derived RPE Cells
Published in Frontiers in neuroscience (29-04-2021)“…Retinitis pigmentosa (RP) is a rare, progressive disease that affects photoreceptors and retinal pigment epithelial (RPE) cells with blindness as a final…”
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Alterations in Circulating Monocytes Predict COVID-19 Severity and Include Chromatin Modifications Still Detectable Six Months after Recovery
Published in Biomedicines (17-09-2021)“…An early analysis of circulating monocytes may be critical for predicting COVID-19 course and its sequelae. In 131 untreated, acute COVID-19 patients at…”
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Understanding cardiovascular disease: a journey through the genome (and what we found there)
Published in Disease models & mechanisms (01-07-2012)“…Cardiovascular disease (CVD) is a major cause of mortality and hospitalization worldwide. Several risk factors have been identified that are strongly…”
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DNA Methylation of miR-7 is a Mechanism Involved in Platinum Response through MAFG Overexpression in Cancer Cells
Published in Theranostics (01-01-2017)“…One of the major limitations associated with platinum use is the resistance that almost invariably develops in different tumor types. In the current study, we…”
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A novel phosphatidylinositol 3-kinase (PI3K) inhibitor directs a potent FOXO-dependent, p53-independent cell cycle arrest phenotype characterized by the differential induction of a subset of FOXO-regulated genes
Published in Breast cancer research : BCR (09-12-2014)“…The activation of the phosphoinositide 3-kinase (PI3K)/AKT signalling pathway is one the most frequent genetic events in breast cancer, consequently the…”
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AG-NGS: a powerful and user-friendly computing application for the semi-automated preparation of next-generation sequencing libraries using open liquid handling platforms
Published in BioTechniques (01-01-2014)“…Next-generation sequencing (NGS) is becoming one of the most widely used technologies in the field of genomics. Library preparation is one of the most…”
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17
Estradiol activates beta-catenin dependent transcription in neurons
Published in PloS one (10-04-2009)“…Estradiol may fulfill a plethora of functions in neurons, in which much of its activity is associated with its capacity to directly bind and dimerize estrogen…”
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Clonal hematopoiesis is not prevalent in Hutchinson-Gilford progeria syndrome
Published in GeroScience (01-04-2023)“…Clonal hematopoiesis of indeterminate potential (CHIP), defined as the presence of somatic mutations in cancer-related genes in blood cells in the absence of…”
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Neutrophil subtypes shape HIV-specific CD8 T-cell responses after vaccinia virus infection
Published in npj vaccines (12-04-2021)“…Neutrophils are innate immune cells involved in the elimination of pathogens and can also induce adaptive immune responses. Nα and Nβ neutrophils have been…”
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Aryl hydrocarbon receptor contributes to the MEK/ERK-dependent maintenance of the immature state of human dendritic cells
Published in Blood (11-04-2013)“…Dendritic cells (DCs) promote tolerance or immunity depending on their maturation state, which is enhanced or accelerated upon MEK-ERK signaling pathway…”
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