Search Results - "Doose, Dennis R"

Effect of Topiramate or Carbamazepine on the Pharmacokinetics of an Oral Contraceptive Containing Norethindrone and Ethinyl Estradiol in Healthy Obese and Nonobese Female Subjects by Doose, Dennis R., Wang, Shean‐Sheng, Padmanabhan, Mukund, Schwabe, Stefan, Jacobs, David, Bialer, Meir

“…Purpose: To study the pharmacokinetics of a combination oral contraceptive (OC) containing norethindrone and ethinyl estradiol during OC monotherapy,…”
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Pharmacokinetic and Metabolic Investigation of Topiramate Disposition in Healthy Subjects in the Absence and in the Presence of Enzyme Induction by Carbamazepine by Britzi, Malka, Perucca, Emilio, Soback, Stefan, Levy, René H., Fattore, Cinzia, Crema, Francesca, Gatti, Giuliana, Doose, Dennis R., Maryanoff, Bruce E., Bialer, Meir

“…Purpose: To characterize the metabolic profile of topiramate (TPM) in humans and to assess the influence of enzyme induction by carbamazepine (CBZ) on the…”
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Topiramate and Phenytoin Pharmacokinetics During Repetitive Monotherapy and Combination Therapy to Epileptic Patients by Sachdeo, R. C., Sachdeo, S. K., Levy, R. H., Streeter, A. J., Bishop, F. E., Kunze, K. L., Mather, G. G., Roskos, L. K., Shen, D. D., Thummel, K. E., Trager, W. F., Curtin, C. R., Doose, Dennis R., Gisclon, L. G., Bialer, Meir

“…Purpose: To evaluate the potential pharmacokinetic interactions between topiramate (TPM) and phenytoin (PHT) in patients with epilepsy by studying their…”
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Topiramate and Lamotrigine Pharmacokinetics during Repetitive Monotherapy and Combination Therapy in Epilepsy Patients by Doose, Dennis R., Brodie, Martin J., Wilson, Elaine A., Chadwick, David, Oxbury, John, Berry, David J., Schwabe, Stefan, Bialer, Meir

“…Purpose: To determine at steady state (in the same group of patients): (a) the pharmacokinetics (PK) of lamotrigine (LTG) with LTG monotherapy, (b) the PK of…”
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A Comparative Study of the Effect of Carbamazepine and Valproic Acid on the Pharmacokinetics and Metabolic Profile of Topiramate at Steady State in Patients with Epilepsy by Mimrod, Dorit, Specchio, Luigi M., Britzi, Malka, Perucca, Emilio, Specchio, Nicola, Neve, Angela La, Soback, Stefan, Levy, René H., Gatti, Giuliana, Doose, Dennis R., Maryanoff, Bruce E., Bialer, Meir

“…Purpose: To compare the influence of enzyme‐inducing comedication and valproic acid (VPA) on topiramate (TPM) pharmacokinetics and metabolism at steady state…”
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Pharmacokinetic interactions of topiramate by BIALER, Meir, DOOSE, Dennis R, MURTHY, Bindu, CURTIN, Christopher, WANG, Shean-Sheng, TWYMAN, Roy E, SCHWABE, Stefan

“…Topiramate is a new antiepileptic drug (AED) that has been approved worldwide (in more than 80 countries) for the treatment of various kinds of epilepsy. It is…”
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Pharmacokinetics of the New Antiepileptic and CNS Drug RWJ‐333369 Following Single and Multiple Dosing to Humans by Yao, Caiping, Doose, Dennis R., Novak, Gerald, Bialer, Meir

“…Purpose: To characterize the pharmacokinetics of the new antiepileptic and CNS drug RWJ‐333369 following single and multiple oral doses to healthy subjects,…”
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Plasma and whole blood pharmacokinetics of topiramate: the role of carbonic anhydrase by Shank, Richard P., Doose, Dennis R., Streeter, Anthony J., Bialer, Meir

“…Topiramate (TPM) is a broad-spectrum antiepileptic drug with various mechanisms of action including an inhibitory effect on some isozymes of carbonic anhydrase…”
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Pharmacokinetics and Tolerability of Rabeprazole in Children 1 to 11 Years Old With Gastroesophageal Reflux Disease by Zannikos, Peter N, Doose, Dennis R, Leitz, Gerhard J, Rusch, Sarah, Gonzalez, Martha D, Solanki, Bhavna, Haddad, Ibrahim, Mulberg, Andrew E

“…ABSTRACT Background: The pharmacokinetics of rabeprazole after a single oral dose and once‐daily administration for 5 consecutive days was characterized in…”
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Pharmacokinetic Interaction Study between the New Antiepileptic and CNS Drug RWJ‐333369 and Carbamazepine in Healthy Adults by Chien, Suchean, Bialer, Meir, Solanki, Bhavna, Verhaeghe, Tom, Doose, Dennis R., Novak, Gerald, Yao, Caiping

“…Purpose: To characterize the possible pharmacokinetic interaction between the new antiepileptic and CNS drug RWJ‐333369 and carbamazepine (CBZ) following…”
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An Interaction Study Between the New Antiepileptic and CNS Drug Carisbamate (RWJ‐333369) and Lamotrigine and Valproic Acid by Chien, Shuchean, Yao, Caiping, Mertens, Annemie, Verhaeghe, Tom, Solanki, Bhavna, Doose, Dennis R., Novak, Gerald, Bialer, Meir

“…Purpose: To characterize possible pharmacokinetic interactions between the new antiepileptic drug carisbamate (RWJ‐333369) and valproic acid (VPA) or…”
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Topiramate Pharmacokinetics in Infants by Glauser, Tracy A., Miles, Michael V., Tang, Peter, Clark, Peggy, McGee, Kathy, Doose, Dennis R.

“…Purpose: This study's goal was to provide preliminary data on the pharmacokinetics of topiramate (TPM) in a cohort of infants (younger than 4 years)…”
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Analysis of topiramate and its metabolites in plasma and urine of healthy subjects and patients with epilepsy by use of a novel liquid chromatography-mass spectrometry assay by BRITZI, Malka, SOBACK, Stefan, ISOHERRANEN, Nina, LEVY, Rene' H, PERUCCA, Emilio, DOOSE, Dennis R, MARYANOFF, Bruce E, BIALER, Meir

“…A novel liquid chromatography-mass spectrometry (LC-MS) method was developed and validated for quantification of topiramate (TPM) and its metabolites…”
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A study of topiramate pharmacokinetics and tolerability in children with epilepsy by Rosenfeld, William E, Doose, Dennis R, Walker, Sally A, Baldassarre, James S, Reife, Ross A

“…The pharmacokinetic and safety profile of topiramate as adjunctive therapy was assessed in pediatric patients with epilepsy in an open-label, 4-week,…”
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The bioavailability and pharmacokinetics of oral and depot intramuscular haloperidol in schizophrenic patients by Nayak, R K, Doose, D R, Nair, N P

“…In a four-segment long-term (greater than or equal to 6 mo) study, patients with schizophrenia received oral haloperidol in single daily doses and subsequently…”
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Effect of Topiramate on the Pharmacokinetics of an Oral Contraceptive Containing Norethindrone and Ethinyl Estradiol in Patients with Epilepsy by Rosenfeld, William E., Doose, Dennis R., Walker, Sally A., Nayak, R. K.

“…Purpose: Because enzyme‐inducing antiepileptic drugs (AEDs) can affect pharmacokinetics of oral contraceptives and thereby cause contraceptive failure, the…”
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Topiramate and Phenytoin Pharmacokinetics During Repetitive Monotherapy and Combination Therapy to Epileptic Patients by Sachdeo, Rajesh C., Sachdeo, S.K., Levy, R.H., Streeter, A.J., Bishop, F.E., Kunze, K.L., Mather, G.G., Roskos, L.K., Shen, D.D., Thummel, K.E., Trager, W.F., Curtin, C. R., Doose, Dennis R., Gisclon, L.G., Bialer, Meir

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Effects of meals and meal composition on the bioavailability of fenretinide by Doose, D R, Minn, F L, Stellar, S, Nayak, R K

“…The effects of meals and meal composition on the bioavailability of fenretinide, N-(4-hydroxyphenyl) retinamide, a synthetic retinoid undergoing clinical…”
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