Search Results - "Dooley, D M"

3-Pyrrolines Are Mechanism-Based Inactivators of the Quinone-Dependent Amine Oxidases but Only Substrates of the Flavin-Dependent Amine Oxidases by Lee, Younghee, Ling, Ke-Qing, Lu, Xingliang, Silverman, Richard B, Shepard, E. M, Dooley, D. M, Sayre, Lawrence M

“…We previously reported that 3-pyrroline and 3-phenyl-3-pyrroline effect a time-dependent inactivation of the copper-containing quinone-dependent amine oxidase…”
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Crystal Structure of the Precursor of Galactose Oxidase: An Unusual Self-Processing Enzyme by Firbank, S. J., Rogers, M. S., Wilmot, C. M., Dooley, D. M., Halcrow, M. A., Knowles, P. F., McPherson, M. J., Phillips, S. E. V.

“…Galactose oxidase (EC 1.1.3.9) is a monomeric enzyme that contains a single copper ion and catalyses the stereospecific oxidation of primary alcohols to their…”
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A Crosslinked Cofactor in Lysyl Oxidase: Redox Function for Amino Acid Side Chains by Wang, Sophie Xuefei, Mure, Minae, Medzihradszky, Katalin F., Burlingame, Alma L., Brown, Doreen E., Dooley, David M., Smith, Alan J., Kagan, Herbert M., Klinman, Judith P.

“…A previously unknown redox cofactor has been identified in the active site of lysyl oxidase from the bovine aorta. Edman sequencing, mass spectrometry,…”
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Identification of topaquinone and its consensus sequence in copper amine oxidases by Janes, S. M, Palcic, M. M, Scaman, C. H, Smith, A. J, Brown, D. E, Dooley, D. M, Mure, M, Klinman, J. P

“…The nature of the active site cofactor and the amino acid sequence flanking this structure have been determined in a range of copper amine oxidases. For…”
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Characterization of the Copper−Sulfur Chromophores in Nitrous Oxide Reductase by Resonance Raman Spectroscopy:  Evidence for Sulfur Coordination in the Catalytic Cluster by Alvarez, Marcela L, Ai, Jingyuan, Zumft, Walter, Sanders-Loehr, Joann, Dooley, David M

“…Nitrous oxide reductase (N2OR) from Pseudomonas stutzeri, a dimeric enzyme with a canonical metal ion content of at least six Cu ions per subunit, contains two…”
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Intramolecular electron transfer rate between active-site copper and topa quinone in pea seedling amine oxidase by Turowski, P.N., McGuirl, M.A., Dooley, D.M.

“…The equilibrium between the two substrate-reduced forms of pea seedling amine oxidase, one containing Cu(II) and reduced 3-(2,4,5-trihydroxyphenyl)-L-alanine…”
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Evidence for copper and 3,4,6-trihydroxyphenylalanine quinone cofactors in an amine oxidase from the Gram-negative bacterium Escherichia coli K-12 by COOPER, R. A, KNOWLES, P. F, BROWN, D. E, MCGUIRL, M. A, DOOLEY, D. M

“…The cofactors present in a amine oxidase induced in Escherichia coli K-12 by growth on 2-phenylethylamine have been studied by spectroscopic methods. E.s.r…”
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Tyrosine codon corresponds to topa quinone at the active site of copper amine oxidases by Mu, D. (University of California, Berkeley, CA), Janes, S.M, Smith, A.J, Brown, D.E, Dooley, D.M, Klinman, J.P

“…The recently discovered organic cofactor of bovine serum amine oxidase, topa quinone, is an uncommon amino acid residue in the polypeptide backbone (Janes, S…”
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Purification and characterization of pea seedling amine oxidase for crystallization studies by McGuirl, M.A. (Montana State University, Bozeman, MT.), McCahon, C.D, McKeown, K.A, Dooley, D.M

“…Pea (Pisum sativum L.) seedling amine oxidase (EC 1.4.3.6) is the first amine oxidase to be crystallized that diffracts to atomic resolution (2.5 angstrom)…”
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Structure and mechanism of galactose oxidase. The free radical site by Baron, A.J. (The University of Leeds, Leeds, UK.), Stevens, C, Wilmot, C, Seneviratne, K.D, Blakeley, V, Dooley, D.M, Phillips, S.E.V, Knowles, P.F, McPherson, M.J

“…Crystallographic and spectroscopic studies on galactose oxidase have shown that the active site involves a free radical on tyrosine 272, one of the ligands…”
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Cofactor processing in galactose oxidase by Firbank, S J, Rogers, M, Hurtado-Guerrero, R, Dooley, D M, Halcrow, M A, Phillips, S E V, Knowles, P F, McPherson, M J

“…Galactose oxidase (GO; EC 1.1.3.9) is a monomeric 68 kDa enzyme that contains a single copper and an amino acid-derived cofactor. The mechanism of this radical…”
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The organic functional group in copper-containing amine oxidases. Resonance Raman spectra are consistent with the presence of topa quinone (6-hydroxydopa quinone) in the active site by BROWN, D. E, MCGUIRL, M. A, DOOLEY, D. M, JANES, S. M, MU, D, KLINMAN, J. P

“…Resonance Raman spectroscopy has been used to probe the structure of the organic cofactor in copper-containing amine oxidases from bovine plasma, porcine…”
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Cloning, sequence analysis, and characterization of the ‘Lysyl Oxidase’ from Pichia Pastoris by Kuchar, Jason A., Dooley, David M.

“…Lysyl oxidase from Pichia pastoris has been successfully overexpressed. EPR and resonance Raman experiments have shown that copper and TPQ are present,…”
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Catalytic Turnover of Substrate Benzylamines by the Quinone-Dependent Plasma Amine Oxidase Leads to H2O2-Dependent Inactivation:  Evidence for Generation of a Cofactor-Derived Benzoxazole by Lee, Younghee, Shepard, Eric, Smith, Jennifer, Dooley, David M, Sayre, Lawrence M

“…Incubation of bovine plasma amine oxidase (BPAO) with benzylamine and various p-substituted analogues results in a time-dependent inactivation that is…”
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Pseudomonas stutzeri N2O Reductase Contains CuA-Type Sites by Scott, Robert A., Zumft, Walter G., Coyle, Catherine L., Dooley, David M.

“…N2O reductase (N2O → N2) is the terminal enzyme in the energy-conserving denitrification pathway of soil and marine denitrifying bacteria. The protein is…”
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Intramolecular electron transfer in the oxidation of amines by methylamine oxidase from Arthrobacter P1 by Dooley, D. M., Brown, Doreen E.

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Child well-being and neighbourhood quality: evidence from the Canadian National Longitudinal Survey of Children and Youth by Curtis, Lori J, Dooley, Martin D, Phipps, Shelley A

“…In this paper, we use the Canadian National Longitudinal Survey of Children and Youth data to examine the links between child well-being and neighbourhood…”
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The Crystal Structure of Pichia pastoris Lysyl Oxidase by Duff, Anthony P, Cohen, Aina E, Ellis, Paul J, Kuchar, Jason A, Langley, David B, Shepard, Eric M, Dooley, David M, Freeman, Hans C, Guss, J. Mitchell

“…Pichia pastoris lysyl oxidase (PPLO) is unique among the structurally characterized copper amine oxidases in being able to oxidize the side chain of lysine…”
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Evidence for Methoxatin (Pyrroloquinolinequinone) as the Cofactor in Bovine Plasma Amine Oxidase from Resonance Raman Spectroscopy by Moog, Richard S., McGuirl, Michele A., Cote, Cheryl E., Dooley, David M.

“…Resonance Raman spectra of the 2,4-dinitrophenylhydrazine derivatives of bovine plasma amine oxidase [amine:oxygen oxidoreductase (deaminating)…”
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Evidence for pyrroloquinolinequinone as the carbonyl cofactor in lysyl oxidase by absorption and resonance Raman spectroscopy by Williamson, P R, Moog, R S, Dooley, D M, Kagan, H M

“…The present study investigated the possibility that pyrroloquinolinequinone (PQQ), an aromatic carbonyl recently indicated to be the carbonyl cofactor in…”
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