Search Results - "Dooijewaard, G"

Tumor Necrosis Factor Induces the Production of Urokinase-Type Plasminogen Activator by Human Endothelial Cells by van Hinsbergh, Victor W.M., van den Berg, Eva A., Fiers, Walter, Dooijewaard, Gerard

“…Endothelial cells play an important role in the regulation of fibrinolysis by the production of several key regulatory proteins. The cytokines tumor necrosis…”
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Protection of single-chain urokinase-type plasminogen activator (scu-PA) in aprotinin treated cardiac surgical patients undergoing cardiopulmonary bypass by Spannagl, M, Dooijewaard, G, Dietrich, W, Kluft, C

“…Intraoperative high-dose aprotinin administration has been shown to reduce the intra-and postoperative blood loss in cardiac surgery. The haemostatic effect…”
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Role of the contact system in fibrinolysis by Kluft, C, Dooijewaard, G, Emeis, J J

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Plasminogen activators in synovial fluid and plasma from patients with arthritis by Brommer, E J, Dooijewaard, G, Dijkmans, B A, Breedveld, F C

“…The activity of plasminogen activators and inhibitors in the synovial fluid and plasma of patients with various forms of chronic arthritis was characterised…”
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Urokinase-type plasminogen activator system predicts risk of cardiovascular events in patients with angina pectoris: results of the ECAPTURE study by de Maat, M P. M, Dooijewaard, G, Meijer, P, Binder, B R, Keber, D, Risberg, B, Kluft, C, Jespersen, J

“…In most Westernized societies cardiovascular diseases are the leading cause of death over the age of 45 years and one-quarter of these deaths occur in men…”
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Physical exercise induces enhancement of urokinase-type plasminogen activator (u-PA) levels in plasma by Dooijewaard, G, de Boer, A, Turion, P N, Cohen, A F, Breimer, D D, Kluft, C

“…The enhancement of the blood fibrinolytic potential by physical exercise is generally attributed to the release of tissue-type plasminogen activator (t-PA)…”
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Identification and genetic analysis of a common molecular variant of histidine-rich glycoprotein with a difference of 2kD in apparent molecular weight by Hennis, B C, van Boheemen, P A, Wakabayashi, S, Koide, T, Hoffmann, J J, Kievit, P, Dooijewaard, G, Jansen, J G, Kluft, C

“…Two forms of histidine-rich glycoprotein (HRG) were detected on SDS-PAGE by silver staining and immunoblotting after isolation of the protein from pooled…”
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Depression of tissue-type plasminogen activator and enhancement of urokinase-type plasminogen activator as an expression of local inflammation by Brommer, E J, Dooijewaard, G, Dijkmans, B A, Breedveld, F C

“…Inflammatory processes are accompanied by extravascular deposition and breakdown of fibrin. We measured fibrinolytic parameters in synovial fluid (SF) and in…”
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Effects of increased liver blood flow on the kinetics and dynamics of recombinant tissue-type plasminogen activator by van Griensven, J M, Huisman, L G, Stuurman, T, Dooijewaard, G, Kroon, R, Schoemaker, R C, Kluft, K, Cohen, A F

“…To investigate the influence of increased liver blood flow on the pharmacokinetics and pharmacodynamics of recombinant tissue-type plasminogen activator…”
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Differences in u-PA and t-PA increase during acute exercise: relation with exercise parameters by van den Burg, P J, Dooijewaard, G, van Vliet, M, Mosterd, W L, Kluft, C, Huisveld, I A

“…Plasma levels of urokinase-type (u-PA Ag) and tissue-type (t-PA Ag) plasminogen activator are both enhanced during physical exercise. Whether, the extent of…”
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Quantitation of urokinase antigen in plasma and culture media by use of an ELISA by Binnema, D J, van Iersel, J J, Dooijewaard, G

“…An ELISA was set up using polyvinylchloride microtiter plates coated with rabbit anti-UK IgG's and affino-purified goat anti-UK IgG's as second antibody…”
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Granulocyte elastase, tumor necrosis factor-alpha and urokinase levels as prognostic markers in severe infection by Philippé, J, Dooijewaard, G, Offner, F, Turion, P, Baele, G, Leroux-Roels, G

“…We have examined the prognostic value of the levels in the blood of granulocyte elastase-alpha 1-proteinase inhibitor (E-alpha 1-PI) complex, tumor necrosis…”
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An amino acid polymorphism in histidine-rich glycoprotein (HRG) explains 59% of the variance in plasma HRG levels by Hennis, B C, Boomsma, D I, van Boheemen, P A, Engesser, L, Kievit, P, Dooijewaard, G, Kluft, C

“…A pedigree-based maximum likelihood method developed by Lange et al. (12) was used to study the contribution of a newly defined di-allelic polymorphism in…”
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Pharmacokinetics of saruplase, a recombinant unglycosylated human single-chain urokinase-type plasminogen activator and its effects on fibrinolytic and haemostatic parameters in healthy male subjects by de Boer, A, Kluft, C, Gerloff, J, Dooijewaard, G, Günzler, W A, Beier, H, van der Meer, F J, Cohen, A F

“…Pharmacokinetics of two doses of the recombinant single-chain urokinase-type plasminogen activator (r-scu-PA) saruplase (40 and 20 mg) and its effect on…”
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Fibrinolytic system during long-distance running in IDDM patients and in healthy subjects by POTTER VAN LOON, R.-J, HEERE, L. P, KLUFT, C, BRIËT, E, DOOIJEWAARD, G, MEINDERS, A. E

“…Fibrinolytic system during long-distance running in IDDM patients and in healthy subjects. B J van Loon , L P Heere , C Kluft , E Briët , G Dooijewaard and A E…”
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An analysis of the activators of single-chain urokinase-type plasminogen activator (scu-PA) in the dextran sulphate euglobulin fraction of normal plasma and of plasmas deficient in factor XII and prekallikrein by Binnema, D J, Dooijewaard, G, Turion, P N

“…An analysis was made of the various possible activators of single-chain urokinase-type plasminogen activator (scu-PA) in the dextran sulphate euglobulin…”
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DDAVP induces systemic release of urokinase-type plasminogen activator by Levi, M, ten Cate, J W, Dooijewaard, G, Sturk, A, Brommer, E J, Agnelli, G

“…The desamino-d-arginine vasopressin (DDAVP) induced enhancement of endogenous fibrinolysis is generally attributed to the release of tissue-type plasminogen…”
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Renal and hepatic handling of endogenous tissue-type plasminogen activator (t-PA) and its inhibitor in man by Brommer, E J, Derkx, F H, Schalekamp, M A, Dooijewaard, G, vd Klaauw, M M

“…In eight male patients with normal liver and kidney function fibrinolytic components were measured in arterial blood and in renal and hepatic vein blood,…”
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Peritoneal fluid and plasma fibrinolytic activity in women with pelvic inflammatory disease by Dörr, P J, Brommer, E J, Dooijewaard, G, Vemer, H M

“…Previous studies have shown that the fibrinolytic activity of peritoneum is depressed in local inflammation. We measured fibrinolytic parameters in peritoneal…”
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Impaired fibrinolysis in the hemolytic-uremic syndrome of childhood by MENZEL, D, LEVI, M, DOOIJEWAARD, G, PETERS, M, TEN CATE, J. W

“…Thrombotic obstruction of glomerular capillaries causes acute renal failure in patients with hemolytic-uremic syndrome (HUS). Recanalization of occluded…”
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