Search Results - "Donzelli, Sara"

Oncogenic MicroRNAs: Key Players in Malignant Transformation by Frixa, Tania, Donzelli, Sara, Blandino, Giovanni

“…MicroRNAs (miRNAs) represent a class of non-coding RNAs that exert pivotal roles in the regulation of gene expression at the post-transcriptional level. MiRNAs…”
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CircPVT1: a pivotal circular node intersecting Long Non-Coding-PVT1 and c-MYC oncogenic signals by Palcau, Alina Catalina, Canu, Valeria, Donzelli, Sara, Strano, Sabrina, Pulito, Claudio, Blandino, Giovanni

“…The role of circular RNAs in oncogenesis has begun to be widely studied in recent years, due to the significant impact that these molecules have in disease…”
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The mutant p53‐ID4 complex controls VEGFA isoforms by recruiting lncRNA MALAT1 by Pruszko, Magdalena, Milano, Elisa, Forcato, Mattia, Donzelli, Sara, Ganci, Federica, Di Agostino, Silvia, De Panfilis, Simone, Fazi, Francesco, Bates, David O, Bicciato, Silvio, Zylicz, Maciej, Zylicz, Alicja, Blandino, Giovanni, Fontemaggi, Giulia

“…The abundant, nuclear‐retained, metastasis‐associated lung adenocarcinoma transcript 1 (MALAT1) has been associated with a poorly differentiated and aggressive…”
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β-arrestin1/YAP/mutant p53 complexes orchestrate the endothelin A receptor signaling in high-grade serous ovarian cancer by Tocci, Piera, Cianfrocca, Roberta, Di Castro, Valeriana, Rosanò, Laura, Sacconi, Andrea, Donzelli, Sara, Bonfiglio, Silvia, Bucci, Gabriele, Vizza, Enrico, Ferrandina, Gabriella, Scambia, Giovanni, Tonon, Giovanni, Blandino, Giovanni, Bagnato, Anna

“…The limited clinical response observed in high-grade serous ovarian cancer (HG-SOC) with high frequency of TP53 mutations (mutp53) might be related to…”
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miR-96-5p targets PTEN expression affecting radio-chemosensitivity of HNSCC cells by Vahabi, Mahrou, Pulito, Claudio, Sacconi, Andrea, Donzelli, Sara, D'Andrea, Marco, Manciocco, Valentina, Pellini, Raul, Paci, Paola, Sanguineti, Giuseppe, Strigari, Lidia, Spriano, Giuseppe, Muti, Paola, Pandolfi, Pier Paolo, Strano, Sabrina, Safarian, Shahrokh, Ganci, Federica, Blandino, Giovanni

“…Head and neck squamous cell carcinoma (HNSCC) is the sixth leading cancer worldwide. They are typically characterized by a high incidence of local recurrence,…”
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Tumor suppressor microRNAs: A novel non-coding alliance against cancer by Blandino, Giovanni, Fazi, Francesco, Donzelli, Sara, Kedmi, Merav, Sas-Chen, Aldema, Muti, Paola, Strano, Sabrina, Yarden, Yosef

“…Tumor initiation and progression are the outcomes of a stepwise accumulation of genetic alterations. Among these, gene amplification and aberrant expression of…”
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miR-15/107 microRNA Gene Group: Characteristics and Functional Implications in Cancer by Turco, Chiara, Donzelli, Sara, Fontemaggi, Giulia

“…The miR-15/107 group of microRNAs (miRNAs) encloses 10 annotated human members and is defined based on the presence of the sequence AGCAGC near the mature…”
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Mutant p53 sustains serine-glycine synthesis and essential amino acids intake promoting breast cancer growth by Tombari, Camilla, Zannini, Alessandro, Bertolio, Rebecca, Pedretti, Silvia, Audano, Matteo, Triboli, Luca, Cancila, Valeria, Vacca, Davide, Caputo, Manuel, Donzelli, Sara, Segatto, Ilenia, Vodret, Simone, Piazza, Silvano, Rustighi, Alessandra, Mantovani, Fiamma, Belletti, Barbara, Baldassarre, Gustavo, Blandino, Giovanni, Tripodo, Claudio, Bicciato, Silvio, Mitro, Nico, Del Sal, Giannino

“…Reprogramming of amino acid metabolism, sustained by oncogenic signaling, is crucial for cancer cell survival under nutrient limitation. Here we discovered…”
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MiRNA-513a-5p inhibits progesterone receptor expression and constitutes a risk factor for breast cancer: the hOrmone and Diet in the ETiology of breast cancer prospective study by Muti, Paola, Donzelli, Sara, Sacconi, Andrea, Hossain, Ahmed, Ganci, Federica, Frixa, Tania, Sieri, Sabina, Krogh, Vittorio, Berrino, Franco, Biagioni, Francesca, Strano, Sabrina, Beyene, Joseph, Yarden, Yosef, Blandino, Giovanni

“…MicroRNAs are regulators of gene expression implicated in cancer development. Using a prospective study, we addressed the possibility that microRNAs serve as…”
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Expression of ID4 protein in breast cancer cells induces reprogramming of tumour-associated macrophages by Donzelli, Sara, Milano, Elisa, Pruszko, Magdalena, Sacconi, Andrea, Masciarelli, Silvia, Iosue, Ilaria, Melucci, Elisa, Gallo, Enzo, Terrenato, Irene, Mottolese, Marcella, Zylicz, Maciej, Zylicz, Alicja, Fazi, Francesco, Blandino, Giovanni, Fontemaggi, Giulia

“…As crucial regulators of the immune response against pathogens, macrophages have been extensively shown also to be important players in several diseases,…”
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PML, YAP, and p73 Are Components of a Proapoptotic Autoregulatory Feedback Loop by Lapi, Eleonora, Di Agostino, Silvia, Donzelli, Sara, Gal, Hilah, Domany, Eytan, Rechavi, Gideon, Pandolfi, Pier Paolo, Givol, David, Strano, Sabrina, Lu, Xin, Blandino, Giovanni

“…p73 has been identified as a structural and functional homolog of the tumor suppressor p53. The transcriptional coactivator Yes-associated protein (YAP) has…”
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A PIK3CA-mutant breast cancer metastatic patient-derived organoid approach to evaluate alpelisib treatment for multiple secondary lesions by Donzelli, Sara, Cioce, Mario, Sacconi, Andrea, Zanconato, Francesca, Daralioti, Theodora, Goeman, Frauke, Orlandi, Giulia, Di Martino, Simona, Fazio, Vito Michele, Alessandrini, Gabriele, Telera, Stefano, Carosi, Mariantonia, Ciliberto, Gennaro, Botti, Claudio, Strano, Sabrina, Piccolo, Stefano, Blandino, Giovanni

“…Keywords: Breast cancer metastases, Organoids, Alpelisib, PIK3CA mutations…”
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Circulating cell free DNA and citrullinated histone H3 as useful biomarkers of NETosis in endometrial cancer by Ronchetti, Livia, Terrenato, Irene, Ferretti, Margherita, Corrado, Giacomo, Goeman, Frauke, Donzelli, Sara, Mandoj, Chiara, Merola, Roberta, Zampa, Ashanti, Carosi, Mariantonia, Blandino, Giovanni, Conti, Laura, Lobascio, Anna Maria, Iacobelli, Marcello, Vizza, Enrico, Piaggio, Giulia, Gurtner, Aymone

“…Cancer mortality is mainly caused by organ failure and thrombotic events. It has been demonstrated that NETosis, a chromatin release mechanism implemented by…”
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TMPRSS2, a SARS-CoV-2 internalization protease is downregulated in head and neck cancer patients by Sacconi, Andrea, Donzelli, Sara, Pulito, Claudio, Ferrero, Stefano, Spinella, Francesca, Morrone, Aldo, Rigoni, Marta, Pimpinelli, Fulvia, Ensoli, Fabrizio, Sanguineti, Giuseppe, Pellini, Raul, Agrawal, Nishant, Izumchenko, Evgeny, Ciliberto, Gennaro, Giannì, Aldo, Muti, Paola, Strano, Sabrina, Blandino, Giovanni

“…SARS-coronavirus-2 enters host cells through binding of the Spike protein to ACE2 receptor and subsequent S priming by the TMPRSS2 protease. We aim to assess…”
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ID4-dependent secretion of VEGFA enhances the invasion capability of breast cancer cells and activates YAP/TAZ via integrin β3-VEGFR2 interaction by Benedetti, Anna, Turco, Chiara, Gallo, Enzo, Daralioti, Theodora, Sacconi, Andrea, Pulito, Claudio, Donzelli, Sara, Tito, Claudia, Dragonetti, Martina, Perracchio, Letizia, Blandino, Giovanni, Fazi, Francesco, Fontemaggi, Giulia

“…Understanding the mechanisms of breast cancer cell communication underlying cell spreading and metastasis formation is fundamental for developing new…”
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Author Correction: Mutant p53 sustains serine-glycine synthesis and essential amino acids intake promoting breast cancer growth by Tombari, Camilla, Zannini, Alessandro, Bertolio, Rebecca, Pedretti, Silvia, Audano, Matteo, Triboli, Luca, Cancila, Valeria, Vacca, Davide, Caputo, Manuel, Donzelli, Sara, Segatto, Ilenia, Vodret, Simone, Piazza, Silvano, Rustighi, Alessandra, Mantovani, Fiamma, Belletti, Barbara, Baldassarre, Gustavo, Blandino, Giovanni, Tripodo, Claudio, Bicciato, Silvio, Mitro, Nico, Del Sal, Giannino

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In vitro antineoplastic effects of brivaracetam and lacosamide on human glioma cells by Rizzo, Ambra, Donzelli, Sara, Girgenti, Vita, Sacconi, Andrea, Vasco, Chiara, Salmaggi, Andrea, Blandino, Giovanni, Maschio, Marta, Ciusani, Emilio

“…Epilepsy is a frequent symptom in patients with glioma. Although treatment with antiepileptic drugs is generally effective in controlling seizures,…”
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Synergistic Effect of Perampanel and Temozolomide in Human Glioma Cell Lines by Salmaggi, Andrea, Corno, Cristina, Maschio, Marta, Donzelli, Sara, D’Urso, Annachiara, Perego, Paola, Ciusani, Emilio

“…Glioblastoma is characterized by a high proliferative rate and drug resistance. The standard of care includes maximal safe surgery, followed by radiotherapy…”
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Epigenetic silencing of miR-145-5p contributes to brain metastasis by Donzelli, Sara, Mori, Federica, Bellissimo, Teresa, Sacconi, Andrea, Casini, Beatrice, Frixa, Tania, Roscilli, Giuseppe, Aurisicchio, Luigi, Facciolo, Francesco, Pompili, Alfredo, Carosi, Maria Antonia, Pescarmona, Edoardo, Segatto, Oreste, Pond, Greg, Muti, Paola, Telera, Stefano, Strano, Sabrina, Yarden, Yosef, Blandino, Giovanni

“…Brain metastasis is a major cause of morbidity and mortality of lung cancer patients. We assessed whether aberrant expression of specific microRNAs could…”
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Correction: Circulating cell free DNA and citrullinated histone H3 as useful biomarkers of NETosis in endometrial cancer by Ronchetti, Livia, Terrenato, Irene, Ferretti, Margherita, Corrado, Giacomo, Goeman, Frauke, Donzelli, Sara, Mandoj, Chiara, Merola, Roberta, Zampa, Ashanti, Carosi, Mariantonia, Blandino, Giovanni, Conti, Laura, Lobascio, Anna Maria, Iacobelli, Marcello, Vizza, Enrico, Piaggio, Giulia, Gurtner, Aymone

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