Search Results - "Donover, P S"

Inhibition of indoleamine 2,3-dioxygenase, an immunoregulatory target of the cancer suppression gene Bin1 , potentiates cancer chemotherapy by Prendergast, George C, Muller, Alexander J, DuHadaway, James B, Donover, P Scott, Sutanto-Ward, Erika

“…Immune escape is a crucial feature of cancer progression about which little is known. Elevation of the immunomodulatory enzyme indoleamine 2,3-dioxygenase…”
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Targeted Disruption of the Murine Bin1/Amphiphysin II Gene Does Not Disable Endocytosis but Results in Embryonic Cardiomyopathy with Aberrant Myofibril Formation by Muller, Alexander J., Baker, Judith F., DuHadaway, James B., Ge, Kai, Farmer, George, Donover, P. Scott, Meade, Raymond, Reid, Christian, Grzanna, Reinhard, Roach, Arthur H., Shah, Neelima, Soler, Alejandro Peralta, Prendergast, George C.

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Increased transversions in a novel mutator colon cancer cell line by ESHLEMAN, J. R, DONOVER, P. S, VEIGL, M. L, LITTMAN, S. J, SWINLER, S. E, LI, G.-M, LUTTERBAUGH, J. D, WILLSON, J. K. V, MODRICH, P, SEDWICK, W. D, MARKOWITZ, S. D

“…We describe a novel mutator phenotype in the Vaco411 colon cancer cell line which increases the spontaneous mutation rate 10-100-fold over background. This…”
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hob1+, the fission yeast homolog of Bin1, is dispensable for endocytosis or actin organization, but required for the response to starvation or genotoxic stress by ROUTHIER, Eric L, DONOVER, P. Scott, PRENDERGAST, George C

“…BAR (Bin/Amphiphysin/Rvs) adapter proteins have been suggested to regulate endocytosis, actin organization, apoptosis, and transcription, but their precise…”
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Diverse hypermutability of multiple expressed sequence motifs present in a cancer with microsatellite instability by Eshleman, J R, Markowitz, S D, Donover, P S, Lang, E Z, Lutterbaugh, J D, Li, G M, Longley, M, Modrich, P, Veigl, M L, Sedwick, W D

“…Colon cancer and an increasing number of other cancers have been found to exhibit instability of DNA microsatellite sequences. Such tumors have been designated…”
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Effect of isopropyl-beta-D-thiogalactopyranosid induction of the lac operon on the specificity of spontaneous and doxorubicin-induced mutations in Escherichia coli by Veigl, M L, Donover, S P, Anderson, R D, Akst, L, Sedwick, C E, Sedwick, W D

“…Previous studies of doxorubicin-induced mutations employing F' lacl/lacO as an endogenous gene target have focused on properties of large deletions with 3'…”
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Cyclin B1 is a critical target of RhoB in the cell suicide program triggered by farnesyl transferase inhibition by KAMASANI, Uma, MINZHOU HUANG, DUHADAWAY, James B, PROCHOWNIK, Edward V, DONOVER, P. Scott, PRENDERGAST, George C

“…Farnesyl transferase inhibitors (FTIs) have displayed limited efficacy in clinical trials, possibly because of their relatively limited cytotoxic effects…”
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Targeted deletion of the suppressor gene bin1/amphiphysin2 accentuates the neoplastic character of transformed mouse fibroblasts by Muller, Alexander J., DuHadaway, James B., Donover, P. Scott, Sutanto-Ward, Erika, Prendergast, George C.

“…The Bin1/Amphiphysin2 gene encodes several alternately spliced BAR adapter proteins that have been implicated in membrane-associated and nuclear processes…”
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