Search Results - "Donovan, Peter"

Phasor approach to fluorescence lifetime microscopy distinguishes different metabolic states of germ cells in a live tissue by Stringari, Chiara, Cinquin, Amanda, Cinquin, Olivier, Digman, Michelle A, Donovan, Peter J, Gratton, Enrico

“…We describe a label-free imaging method to monitor stem-cell metabolism that discriminates different states of stem cells as they differentiate in living…”
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Regulation of Self‐Renewal and Pluripotency by Sox2 in Human Embryonic Stem Cells by Fong, Helen, Hohenstein, Kristi A., Donovan, Peter J.

“…Human embryonic stem (hES) cells, derived from blastocysts, are capable of unlimited self‐renewal and differentiation into all cell lineages of the body…”
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Metabolic trajectory of cellular differentiation in small intestine by Phasor Fluorescence Lifetime Microscopy of NADH by Stringari, Chiara, Edwards, Robert A., Pate, Kira T., Waterman, Marian L., Donovan, Peter J., Gratton, Enrico

“…There is a lack of fast and high resolution methods to measure metabolic activity of single cells in their native environment. Here we develop a…”
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Label-free separation of human embryonic stem cells and their differentiating progenies by phasor fluorescence lifetime microscopy by Stringari, Chiara, Sierra, Robert, Donovan, Peter J, Gratton, Enrico

“…We develop a label-free optical technique to image and discriminate undifferentiated human embryonic stem cells (hESCs) from their differentiating progenies …”
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Trends in opioid prescribing in Australia: a systematic review by Donovan, Peter J, Arroyo, David, Pattullo, Champika, Bell, Anthony

“…Objective This review systematically identified studies that estimated the prevalence of prescription opioid use in Australia, assessed the prevalence…”
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John D. Gearhart (1943-2020) by Donovan, Peter J, Zaret, Kenneth S

“…Pioneer of human pluripotent stem cell research John Gearhart, the developmental biologist who first derived human pluripotent stem cells from primordial germ…”
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Monitoring for valproate and phenytoin toxicity in hypoalbuminaemia: A retrospective cohort study by Madan, Arushi, Donovan, Peter J., Risetto, Tracy, Trenerry, Helen, Lander, Cecilie M.

“…Aims Equations to calculate albumin‐adjusted total concentrations have been validated to correlate with measured free concentrations for both phenytoin and…”
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Characterization of a chromatin‐associated TCF7L1 complex in human embryonic stem cells by Vuong, Linh M., Pan, Songqin, Sierra, Robert A., Waterman, Marian L., Gershon, Paul D., Donovan, Peter J.

“…Human embryonic stem cells (hESCs) resemble the pluripotent epiblast cells found in the early postimplantation human embryo and represent the “primed” state of…”
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Proteome Profile of Endogenous Retrotransposon‐Associated Complexes in Human Embryonic Stem Cells by Vuong, Linh M., Pan, Songqin, Donovan, Peter J.

“…Long Interspersed Element‐1 (LINE‐1 or L1) are transposable elements similar to retroviruses that have existed in the genome of primates for millions of years…”
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PTHrP-Mediated Hypercalcemia: Causes and Survival in 138 Patients by Donovan, Peter J, Achong, Naomi, Griffin, Katherine, Galligan, John, Pretorius, Carel J, McLeod, Donald S. A

“…Context: Hypercalcemia is a common complication of cancer with PTHrP an important mediator. Literature on the underlying causes of PTHrP-mediated…”
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Multidisciplinary quality improvement programme for older patients admitted to a vascular surgery ward by Mudge, Alison M., McRae, Prue, Donovan, Peter J., Reade, Michael C.

“…Background Older vascular surgical patients are at high risk of hospital‐associated complications and prolonged stays. Aims To implement a multidisciplinary…”
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Can a novel constructivist theory-informed feedback intervention reduce prescribing errors ? A pre-post study by Coombes, Ian, Donovan, Peter, Bullock, Brooke, Mitchell, Charles, Noble, Christy

“…Medical interns (interns) find prescribing challenging and many report lacking readiness when commencing work. Errors in prescribing puts patients' safety at…”
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Mitochondrial Akt Signaling Modulated Reprogramming of Somatic Cells by Chen, Yu-Han, Su, Ching-Chieh, Deng, Wu, Lock, Leslie F., Donovan, Peter J., Kayala, Matthew A., Baldi, Pierre, Lee, Hsiao-Chen, Chen, Yumay, Wang, Ping H.

“…The signaling mechanisms controlling somatic cell reprogramming are not fully understood. In this study, we report a novel role for mitochondrial Akt1…”
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Cost–utility analysis comparing radioactive iodine, anti-thyroid drugs and total thyroidectomy for primary treatment of Graves’ disease by Donovan, Peter J, McLeod, Donald S A, Little, Richard, Gordon, Louisa

“…Objective Little data is in existence about the most cost-effective primary treatment for Graves’ disease. We performed a cost–utility analysis comparing…”
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Protein kinase A regulates resumption of meiosis by phosphorylation of Cdc25B in mammalian oocytes by Pirino, Giorgia, Wescott, Melanie P., Donovan, Peter J.

“…In mammalian oocytes, meiosis arrests at prophase I. Meiotic resumption requires activation of Maturation-Promoting Factor (MPF), comprised of a catalytic…”
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Rescue of radiation-induced cognitive impairment through cranial transplantation of human embryonic stem cells by Acharya, Munjal M, Christie, Lori-Ann, Lan, Mary L, Donovan, Peter J, Cotman, Carl W, Fike, John R, Limoli, Charles L

“…Cranial irradiation remains a frontline treatment for the control of tumor growth, and individuals surviving such treatments often manifest various degrees of…”
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Expression of Oct4 in human embryonic stem cells is dependent on nanotopographical configuration by Kong, Yen P., Tu, Christina H., Donovan, Peter J., Yee, Albert F.

“…The fate of adult stem cells can be influenced by physical cues, including nanotopography. However, the response of human embryonic stem cells (hESCs) to…”
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Toilet Paper, Minced Meat and Diabetes Medicines: Australian Panic Buying Induced by COVID-19 by Engstrom, Teyl, Baliunas, Dolly O, Sly, Benjamin P, Russell, Anthony W, Donovan, Peter J, Krausse, Heike K, Sullivan, Clair M, Pole, Jason D

“…The COVID-19 pandemic has impacted the management of non-communicable diseases in health systems around the world. This study aimed to understand the impact of…”
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Neurotrophins mediate human embryonic stem cell survival by Donovan, Peter J, Pyle, April D, Lock, Leslie F

“…Growth of human embryonic stem (hES) cells as a pluripotent population requires a balance between survival, proliferation and self-renewal signals. Here we…”
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TCF7L1 suppresses primitive streak gene expression to support human embryonic stem cell pluripotency by Sierra, Robert A, Hoverter, Nathan P, Ramirez, Ricardo N, Vuong, Linh M, Mortazavi, Ali, Merrill, Bradley J, Waterman, Marian L, Donovan, Peter J

“…Human embryonic stem cells (hESCs) are exquisitely sensitive to WNT ligands, which rapidly cause differentiation. Therefore, hESC self-renewal requires robust…”
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