Search Results - "Donovan, Lene Lundgaard"

A Single Dose of Psilocybin Increases Synaptic Density and Decreases 5-HT2A Receptor Density in the Pig Brain by Raval, Nakul Ravi, Johansen, Annette, Donovan, Lene Lundgaard, Ros, Nídia Fernandez, Ozenne, Brice, Hansen, Hanne Demant, Knudsen, Gitte Moos

“…A single dose of psilocybin, a psychedelic and serotonin 2A receptor (5-HT2AR) agonist, may be associated with antidepressant effects. The mechanism behind its…”
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Maternal Separation Followed by Chronic Mild Stress in Adulthood Is Associated with Concerted Epigenetic Regulation of AP-1 Complex Genes by Lundgaard Donovan, Lene, Henningsen, Kim, Flou Kristensen, Anne, Wiborg, Ove, Nieland, John Dirk, Lichota, Jacek

“…Depression is one of the most prevalent mental diseases worldwide. Patients with psychiatric diseases often have a history of childhood neglect, indicating…”
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Effects of a single dose of psilocybin on behaviour, brain 5-HT2A receptor occupancy and gene expression in the pig by Donovan, Lene Lundgaard, Johansen, Jens Vilstrup, Ros, Nídia Fernandez, Jaberi, Elham, Linnet, Kristian, Johansen, Sys Stybe, Ozenne, Brice, Issazadeh-Navikas, Shohreh, Hansen, Hanne Demant, Knudsen, Gitte Moos

“…•Pigs respond to 0.08 mg/kg psilocybin i.v. with headshakes, scratching and rubbing behaviour.•A similar dose produce a cerebral 5-HT2A receptor occupancy of…”
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Kinetic models for estimating occupancy from single-scan PET displacement studies by Laurell, Gjertrud Louise, Plavén-Sigray, Pontus, Johansen, Annette, Raval, Nakul Ravi, Nasser, Arafat, Aabye Madsen, Clara, Madsen, Jacob, Hansen, Hanne Demant, Donovan, Lene Lundgaard, Knudsen, Gitte Moos, Lammertsma, Adriaan A, Ogden, R Todd, Svarer, Claus, Schain, Martin

“…The traditional design of PET target engagement studies is based on a baseline scan and one or more scans after drug administration. We here evaluate an…”
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A Single Dose of Psilocybin Increases Synaptic Density and Decreases 5-HT 2A Receptor Density in the Pig Brain by Raval, Nakul Ravi, Johansen, Annette, Donovan, Lene Lundgaard, Ros, Nídia Fernandez, Ozenne, Brice, Hansen, Hanne Demant, Knudsen, Gitte Moos

“…A single dose of psilocybin, a psychedelic and serotonin 2A receptor (5-HT R) agonist, may be associated with antidepressant effects. The mechanism behind its…”
Get full text

Effects of a single dose of psilocybin on behaviour, brain 5-HT 2A receptor occupancy and gene expression in the pig by Donovan, Lene Lundgaard, Johansen, Jens Vilstrup, Ros, Nídia Fernandez, Jaberi, Elham, Linnet, Kristian, Johansen, Sys Stybe, Ozenne, Brice, Issazadeh-Navikas, Shohreh, Hansen, Hanne Demant, Knudsen, Gitte Moos

“…Psilocybin has in some studies shown promise as treatment of major depressive disorder and psilocybin therapy was in 2019 twice designated as breakthrough…”
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