Search Results - "Donovan, Aaron"
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General Installation of (4H)‑Imidazolone cis-Amide Bioisosteres Along the Peptide Backbone
Published in Journal of the American Chemical Society (01-05-2024)“…Imidazolones represent an important class of heterocycles present in a wide range of pharmaceuticals, metabolites, and bioactive natural products and serve as…”
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Journal Article -
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Complementary Strategies for Installation of Thioimidates into Peptide Backbones
Published in Journal of organic chemistry (18-10-2024)“…Thioimidates are a precursor and synthetic branch point to access either thioamide or amidine isosteres of the native amide (peptide bond). Previous syntheses…”
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Journal Article