Search Results - "Donoghue, Jacqueline"

Comparative toxicity of synchrotron and conventional radiation therapy based on total and partial body irradiation in a murine model by Smyth, Lloyd M. L., Donoghue, Jacqueline F., Ventura, Jessica A., Livingstone, Jayde, Bailey, Tracy, Day, Liam R. J., Crosbie, Jeffrey C., Rogers, Peter A. W.

“…Synchrotron radiation can facilitate novel radiation therapy modalities such as microbeam radiation therapy (MRT) and high dose-rate synchrotron broad-beam…”
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Targeted drug delivery using genetically engineered diatom biosilica by Delalat, Bahman, Sheppard, Vonda C., Rasi Ghaemi, Soraya, Rao, Shasha, Prestidge, Clive A., McPhee, Gordon, Rogers, Mary-Louise, Donoghue, Jacqueline F., Pillay, Vinochani, Johns, Terrance G., Kröger, Nils, Voelcker, Nicolas H.

“…The ability to selectively kill cancerous cell populations while leaving healthy cells unaffected is a key goal in anticancer therapeutics. The use of…”
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Mesenchymal Niche-Derived Neuregulin-1 Drives Intestinal Stem Cell Proliferation and Regeneration of Damaged Epithelium by Jardé, Thierry, Chan, Wing Hei, Rossello, Fernando J., Kaur Kahlon, Tanvir, Theocharous, Mandy, Kurian Arackal, Teni, Flores, Tracey, Giraud, Mégane, Richards, Elizabeth, Chan, Eva, Kerr, Genevieve, Engel, Rebekah M., Prasko, Mirsada, Donoghue, Jacqueline F., Abe, Shin-ichi, Phesse, Toby J., Nefzger, Christian M., McMurrick, Paul J., Powell, David R., Daly, Roger J., Polo, Jose M., Abud, Helen E.

“…Epidermal growth factor (EGF) maintains intestinal stem cell (ISC) proliferation and is a key component of organoid growth media yet is dispensable for…”
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Correction: Dilated Thin-Walled Blood and Lymphatic Vessels in Human Endometrium: A Potential Role for VEGF-D in Progestin-Induced Break-Through Bleeding by Donoghue, Jacqueline F, McGavigan, C. Jay, Lederman, Fiona L, Cann, Leonie M, Fu, Lulu, Dimitriadis, Evdokia, Girling, Jane E, Rogers, Peter A. W

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Predicting disease recurrence in patients with endometriosis: an observational study by Holdsworth-Carson, Sarah J, Chung, Jessica, Machalek, Dorothy A, Li, Rebecca, Jun, Byung Kyu, Griffiths, Meaghan J, Churchill, Molly, McCaughey, Tristan, Nisbet, Debbie, Dior, Uri, Donoghue, Jacqueline F, Montgomery, Grant W, Reddington, Charlotte, Girling, Jane E, Healey, Martin, Rogers, Peter A W

“…Despite surgical and pharmacological interventions, endometriosis can recur. Reliable information regarding risk of recurrence following a first diagnosis is…”
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Gene expression of the endocannabinoid system in endometrium through menstrual cycle by Tanaka, Keisuke, Amoako, Akwasi A., Mortlock, Sally, Rogers, Peter A. W., Holdsworth-Carson, Sarah J., Donoghue, Jacqueline F., Teh, Wan Tinn, Montgomery, Grant W., McKinnon, Brett

“…Endocannabinoids mediate cellular functions and their activity is controlled by a complex system of enzymes, membrane receptors and transport molecules…”
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Spatially Fractionated X-Ray Microbeams Elicit a More Sustained Immune and Inflammatory Response in the Brainstem than Homogenous Irradiation by Smyth, Lloyd M. L., Crosbie, Jeffrey C., Sloggett, Clare, Rogers, Peter A. W., Donoghue, Jacqueline F.

“…Synchrotron microbeam radiation therapy (MRT) is a preclinical irradiation technique which could be used to treat intracranial malignancies. The goal of this…”
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Elucidating the role of long intergenic non-coding RNA 339 in human endometrium and endometriosis by Holdsworth-Carson, Sarah J, Churchill, Molly, Donoghue, Jacqueline F, Mortlock, Sally, Fung, Jenny N, Sloggett, Clare, Chung, Jessica, Cann, Leonie, Teh, Wan Tinn, Campbell, Katie-Rose, Luwor, Rodney, Healey, Martin, Montgomery, Grant, Girling, Jane E, Rogers, Peter A W

“…Endometriosis is a complex disease, influenced by genetic factors. Genetic markers associated with endometriosis exist at chromosome 1p36.12 and lead to…”
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Peripheral, Central, and Cross Sensitization in Endometriosis-Associated Pain and Comorbid Pain Syndromes by McNamara, Helen C., Frawley, Helena C., Donoghue, Jacqueline F., Readman, Emma, Healey, Martin, Ellett, Lenore, Reddington, Charlotte, Hicks, Lauren J., Harlow, Keryn, Rogers, Peter A. W., Cheng, Claudia

“…Endometriosis-associated pain and the mechanisms responsible for its initiation and persistence are complex and difficult to treat. Endometriosis-associated…”
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Activation of ERBB4 in Glioblastoma Can Contribute to Increased Tumorigenicity and Influence Therapeutic Response by Donoghue, Jacqueline F, Kerr, Lauren T, Alexander, Naomi W, Greenall, Sameer A, Longano, Anthony B, Gottardo, Nicholas G, Wang, Rong, Tabar, Viviane, Adams, Timothy E, Mischel, Paul S, Johns, Terrance G

“…Glioblastoma (GBM) is often resistant to conventional and targeted therapeutics. ErbB2 Receptor Tyrosine Kinase 4 (ERBB4) is expressed throughout normal brain…”
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Non-agonistic bivalent antibodies that promote c-MET degradation and inhibit tumor growth and others specific for tumor related c-MET by Greenall, Sameer A, Gherardi, Ermanno, Liu, Zhanqi, Donoghue, Jacqueline F, Vitali, Angela A, Li, Qian, Murphy, Roger, Iamele, Luisa, Scott, Andrew M, Johns, Terrance G

“…The c-MET receptor has a function in many human cancers and is a proven therapeutic target. Generating antagonistic or therapeutic monoclonal antibodies (mAbs)…”
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The γH2AX DSB marker may not be a suitable biodosimeter to measure the biological MRT valley dose by Ventura, Jessica A., Donoghue, Jacqueline F., Nowell, Cameron J., Cann, Leonie M., Day, Liam R. J., Smyth, Lloyd M. L., Forrester, Helen B., Rogers, Peter A. W., Crosbie, Jeffrey C.

“…γH2AX biodosimetry has been proposed as an alternative dosimetry method for microbeam radiation therapy (MRT) because conventional dosimeters, such as…”
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Radiotherapy exposure directly damages the uterus and causes pregnancy loss by Griffiths, Meaghan J, Marshall, Sarah A, Cousins, Fiona L, Alesi, Lauren R, Higgins, Jordan, Giridharan, Saranya, Sarma, Urooza C, Menkhorst, Ellen, Zhou, Wei, Care, Alison S, Donoghue, Jacqueline F, Holdsworth-Carson, Sarah J, Rogers, Peter Aw, Dimitriadis, Evdokia, Gargett, Caroline E, Robertson, Sarah A, Winship, Amy L, Hutt, Karla J

“…Female cancer survivors are significantly more likely to experience infertility than the general population. It is well established that chemotherapy and…”
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6731 Development of the ‘unique’ clinic – a multidisciplinary clinic for patients with single-ventricle heart disease in a tertiary paediatric cardiology centre by Pentony, Michaela, Donoghue, Jacqueline O’, Crumlish, Kathleen, Shaw, Kathyrn, Casey, Annemarie, Matthews, Catherine, Tuohy, Michelle, Dallape, Sara, MacAuley, Yvonne, Fitzgerald, Kirsten, Franklin, Orla

“…ObjectivesPatients with single ventricle (SV) physiology are a unique cohort of patients, many of whom have undergone or are currently undergoing a staged…”
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Dilated thin-walled blood and lymphatic vessels in human endometrium: a potential role for VEGF-D in progestin-induced break-through bleeding by Donoghue, Jacqueline F, McGavigan, C Jay, Lederman, Fiona L, Cann, Leonie M, Fu, Lulu, Dimitriadis, Eva, Girling, Jane E, Rogers, Peter A W

“…Progestins provide safe, effective and cheap options for contraception as well as the treatment of a variety of gynaecological disorders. Episodes of irregular…”
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The identification of mitochondrial DNA variants in glioblastoma multiforme by Yeung, Ka Yu, Dickinson, Adam, Donoghue, Jacqueline F, Polekhina, Galina, White, Stefan J, Grammatopoulos, Dimitris K, McKenzie, Matthew, Johns, Terrance G, St John, Justin C

“…Mitochondrial DNA (mtDNA) encodes key proteins of the electron transfer chain (ETC), which produces ATP through oxidative phosphorylation (OXPHOS) and is…”
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Differential Sensitivity of Human Hepatocellular Carcinoma Xenografts to an IGF-II Neutralizing Antibody May Involve Activated STAT3 by Greenall, Sameer A., Donoghue, Jacqueline, Johns, Terrance G., Adams, Timothy E.

“…Hepatocellular carcinoma (HCC) is highly refractory to current therapeutics used in the clinic. DX-2647, a recombinant human antibody, potently neutralizes the…”
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Lymphangiogensis of normal endometrium and endometrial adenocarcinoma by Donoghue, Jacqueline F., Lederman, Fiona L., Susil, Beatrice J., Rogers, Peter A.W.

“…BACKGROUND Information about lymphatics and lymphangiogenesis in the human endometrium is limited. We investigated the distribution of endometrial lymphatic…”
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Axitinib Has Antiangiogenic and Antitumorigenic Activity in Myxoid Liposarcoma by Kerr, Lauren T., Donoghue, Jacqueline F., Wilding, Alexander L., Johns, Terrance G.

“…Myxoid liposarcoma is a rare form of soft-tissue sarcoma. Although most patients initially respond well to treatment, approximately 21% relapse, highlighting…”
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Endometrial angiogenesis, vascular maturation, and lymphangiogenesis by Rogers, Peter A W, Donoghue, Jacqueline F, Walter, Lisa M, Girling, Jane E

“…Angiogenesis, arteriogenesis or vessel maturation, and lymphangiogenesis comprise a continuum of vascular development, with overlap and interaction between the…”
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